eChapters

1. An imaginary line joining the points of equal elevation on the surface of the earth represents_____________. (Contour lines)
2. The vertical distance between consecutive contours lines is called_____________. (Contour interval)
3. When measured with a compass, the line of sight that run midway between due North and due West has a bearing of_____________. (N 45 degree W)
4. A survey of a large area which consider the earth’s curvature is called a _____________ survey. (Geodetic)
5. The distinctive feature of topographic maps is the_____________ of the land. (Shape or Contour)
6. The colour used to depict fence lines and important roads on a topographic map is _____________ and_____________. (Red and black)
7. A surveyor’s chain is divided into links and each link is_____________ long. (0.66 feet)
8. A body of water on a topographic map is presented by_____________ colour. (Blue)
9. On a topographic map a ploughed field would be sown as_____________ colour. (White)

Aquaculture, the cultivation of aquatic organisms such as fish, shellfish, and seaweed, has grown exponentially in recent decades due to overfishing and the increasing demand for seafood. This chapter provides a comprehensive overview of aquaculture practices, including its methods, species, and technological advancements. It also delves into the environmental impacts associated with aquaculture, both positive and negative. Key issues such as habitat destruction, water pollution, genetic diversity, and using wild fish for feed are discussed, along with mitigation strategies and sustainable practices. The chapter concludes with a discussion on policy frameworks and future directions for minimizing the environmental footprint of aquaculture while maximizing its potential to contribute to global food security.

1. Introduction

Aquaculture, or the farming of aquatic organisms, has become a significant component of the global food system. It encompasses the breeding, rearing, and harvesting of fish, shellfish, algae, and other aquatic organisms in various aquatic environments including freshwater, brackish water, and marine water. Aquaculture's rapid expansion has been driven by the decline in wild fish stocks due to overfishing, as well as the growing global population and increased per capita consumption of seafood (FAO, 2020).

Precision fisheries, a concept adapted from precision agriculture, involves the application of advanced technologies and data-driven approaches to optimize fishing operations and resource management. This chapter explores the potential of precision fisheries as the future of fishing, offering benefits such as increased efficiency, reduced environmental impact, and improved sustainability. By integrating cutting-edge technologies such as remote sensing, GIS (Geographic Information Systems), IoT (Internet of Things), and machine learning, precision fisheries aim to enhance decision-making, maximize yield, and minimize resource wastage. The chapter discusses key components of precision fisheries, including real-time monitoring, predictive modeling, and targeted harvesting, and examines their implications for the fishing industry, ecosystems, and coastal communities. Furthermore, the chapter highlights challenges and opportunities associated with the adoption of precision fisheries and provides recommendations for policymakers, researchers, and stakeholders to harness its full potential for sustainable fisheries management and food security.

The Indian farm women have extensive workloads with triple responsibility for farm, household and community. Gradually their work is becoming harder due to climate change, degradation of natural resources, natural calamities, male migration and changing agricultural technologies. Women are extensively involved in crop production, horticulture, livestock management, post harvest operation, fisheries, agroforestry and household activities. Majority of their time is devoted towards collection of fuel, fodder and water, growing vegetables in homestead and rearing backyard poultry. They also considerably contribute for household income as agriculture wage earners and through cottage industry.

Women play a significant and crucial role in agricultural development and allied fields. The nature and extent of women’s involvement in agriculture varies greatly from region to region. But regardless of these variations, women are actively involved in various agricultural activities.

As per Census 2011, out of total female main workers, 55 per cent were agricultural labourers and 24 per cent were cultivators. However, only 12.8 per cent of the operational holdings were owned by women, which reflect the gender disparity in ownership of landholdings in agriculture. Moreover, there is concentration of operational holdings (25.7 per cent) by women in the marginal and small holdings categories. Worker Population Ratio (WPR) of women (24 %) is lower as against men (54.4 %) in the country. The workforce participation rate for rural females is higher at 30.5 percent against urban women participation rate of 20.20 percent (Mo SPI, 2022-23). As per the Annual Periodic Labour Force Survey (PLFS) Report 2022-23, agriculture had the highest estimated percentage distribution of female workers, ie. 64.3 %, with 76.2 % in rural areas and 11.7 % in urban areas.

Climate change significantly impacts agriculture, altering growing conditions, crop yields, and the livelihoods of farmers. Rising temperatures and shifting precipitation patterns can lead to more frequent and intense droughts, floods, and storms, which disrupt planting and harvesting schedules and reduce crop productivity. Changes in temperature and precipitation can also exacerbate pest and disease pressures, making it harder for farmers to protect their crops. Additionally, the increased frequency of extreme weather events can damage infrastructure and soil health, further challenging agricultural systems. These effects pose serious threats to food security, necessitating the development of climate-resilient farming practices and crop varieties, as well as policies that support sustainable agricultural development and climate adaptation.

The climate change is not “gender neutral”. Women and girls experience the greatest impacts of climate change, which amplifies existing gender inequalities and poses unique threats to their livelihoods, health, and safety.

Climate change effect on women

1. Reduced Agricultural Productivity: Climate change leads to crop failures, reduced yields, and changed growing seasons, affecting women’s income and food security.

2. Increased Water Scarcity: Changes in precipitation patterns and increased evaporation lead to water scarcity, forcing women to travel farther for water, reducing their time for other activities.

3. Soil Erosion and Degradation: Flooding and erosion caused by climate change degrade soil quality, reducing fertility and affecting crop growth, further threatening women’s livelihoods.

Introduction

In the face of a burgeoning global population, the imperative for robust advancements in food production, especially within the aquaculture industry, is more pressing than ever. The expansion of this industry necessitates a nuanced consideration of environmental, economic, and social factors underpinned by a commitment to sustainable development. However, the intensification of aquaculture, particularly in coastal regions, poses long-term environmental risks due to increased organic matter in water, demanding innovative solutions.

In recent decades, recirculating systems have emerged as a step toward sustainable aquaculture, offering an effective approach to control wastewater. High operating costs have hindered widespread adoption despite their potential, particularly in developing countries. Enter the need for a game-changing, cost effective, and environmentally friendly technology that resonates with farmers on a large scale. This is where the Biofloc system, or Biofloc technology (BFT), takes center stage. A beacon of cost-effectiveness, sustainability, and environmental friendliness, the BFT reduces water exchange to almost zero and slashes artificial feeding ratios. This revolutionary system enhances water quality and generates microbial protein for aquatic species, addressing critical challenges faced by the aquaculture industry.

Introduction

India has a coastline of 8,118 km, with an exclusive economic zone (EEZ) of 2.02 million sq km and a continental shelf area of 3,72,424 km², spread across 9 maritime States and seven Union Territories, including the islands of Andaman and Nicobar, and Lakshadweep. India represents 2.5 percent of the world’s landmass and supports a population of over one billion people. India is also one of 17 mega-biodiverse countries in the world, with 7.8% of the recorded species of the world, including 45,500 recorded species of plants and 91,000 recorded species of animals. The marine ecosystem is extremely diverse, attributed to the geomorphologic and climatic variations along the coast. The coastal and marine habitat includes near shore, gulf waters, creeks, tidal flats, mud flats, coastal dunes, mangroves, marshes, wetlands, seaweed and sea grass beds, deltaic plains, estuaries, lagoons and coral reefs.

Importance of Study

The detailed studies on the coastal and marine biodiversity of the Indian mainland are lacking, and so these habitats and the biodiversity are represented poorly. It is obvious that the biodiversity is distributed widely among different associated habitats and conserving a single area would never support all the important species and ecological processes worth protecting. Furthermore, biodiversity can only be conserved by preventing habitat loss and by restoration. The importance of any single species in the functioning of an ecosystem may not be high, but protection of a mosaic of habitats will certainly preserve diversity among the species of conservation importance. Also, to achieve the Biodiversity Aichi Targets with reference to the marine environment are to preserve ecologically sensitive areas and maintain the health of the marine environment by protection, sustainable use and conservation of marine living resources.

Introduction

Aquaculture stands as the swiftest expanding sector within the food industry, with an escalating per capita consumption of fish-derived animal protein. India, as the world's third-largest fish producer, contributes significantly to this trend, boasting a fish production of 16.24 million tons, which corresponds to 8% of the global fish production. Nevertheless, several challenges persist and must be addressed, including the absence of species-specific or functional feeds, the dearth of genetically modified strains or breeds, the availability of high-quality fish species, and the rising incidence of fish diseases. Recent strides in "omics" technologies have furnished a potent toolkit and conceptual framework that enables the comprehensive dissection of the phenotypic and functional networks of genes and proteins within cells or organisms (Mohanty et al., 2019). This innovative research domain has spawned technological advancements that harness the power of "omics" to scrutinize diverse biological systems (Ning and Lo, 2010). The integration of "omics" in aquaculture research has effectively surmounted numerous challenges related to production and reproduction, thereby ensuring its relevance and economic viability. This technology empowers researchers to analyze an array of molecules on a massive scale, marking an early and groundbreaking technological leap forward in this field.

Introduction

Aquaculture, involving the cultivation of fish, crustaceans, molluscs, and aquatic plants, has become indispensable for global food security and employment. However, the intensification of aquaculture practices, characterized by high stocking densities, has led to increased stress among farmed organisms, which in turn makes them more susceptible to diseases. Disease outbreaks in aquaculture can have devastating effects, necessitating both prophylactic and therapeutic measures to maintain the health and productivity of these organisms.

Prophylactic measures, such as vaccines and immunostimulants, play a vital role in preventing disease outbreaks. For instance, vaccines targeting common bacterial pathogens like Aeromonas hydrophila are widely used in fish farming. Immunostimulants like beta-glucans are also administered to enhance the immune response of aquatic organisms. On the therapeutic front, antibiotics remain the most commonly used agents to treat infections once they occur. However, the extensive use of antibiotics has led to several significant issues. Firstly, antimicrobial resistance (AMR) has emerged as a major concern, with the excessive use of antibiotics in aquaculture contributing to the development of resistant bacterial strains. These resistant pathogens can spread to other aquatic organisms and humans, posing a serious public health risk. Secondly, the presence of antibiotic residues in seafood can lead to export rejections, as many countries enforce strict regulations on such residues. This can result in considerable economic losses for aquaculture producers. Lastly, residual antibiotics in seafood can cause allergic reactions in consumers and contribute to the emergence of antibiotic-resistant infections.

Introduction

The global food system is anticipated to supply safe and nutritious food to a population that is expected to increase from 7.5 billion now to approximately 10 billion by 2050. Not only will there be more mouths to feed, but as incomes rise in rising and developing nations, demand for meat, fish, and dairy will rise as well (Brooks et al., 2019). Demand for agricultural commodities is rising rapidly as the world's population grows. Agriculture’s deep connections to the world economy, human societies, and biodiversity make it one of the most important frontiers for conservation around the globe (world wildlife).

Today's connected world has given entrepreneurs millions of new places to start small businesses, and the Internet has a lot of information to help them. Also, the internet has made it easier for business owners to connect with their peers, learn from their mistakes, and use their good decisions as a guide for their paths.

Introduction

Farmers Producer Organisations are associations of farmers and other rural producers formed based on membership to advance the members' common interests, engage in mutually beneficial technical and economic activities, and foster and sustain relationships with other organisations active in the same economic and institutional sphere. Farmer Producer Organisations (FPO) are a way for farmers, especially those on the margins of the industry, to band together and establish a strong front against the myriad problems plaguing the agricultural sector, including a lack of capital, knowledge, and access to markets. To better organise farmers, increase their ability to pool their resources, and increase their competitive edge in the marketplace, the Indian government's Department of Agriculture and Cooperation (DAC) has determined that Farmer Producer Organisations incorporated under the Companies Act, 1956 are the best vehicle for doing so.

Background

More than 85% of India's 12.5 million agricultural households are classified as small and marginal farmers because they own less than two hectares of land. Every farmer, on average, owns 1.33 hectares of land. For farmers, investing in cutting-edge farming techniques and high-yielding inputs like seeds and fertiliser is simply not feasible in the current economic climate. They also don't make much money off their marketable surplus when they sell it off piece by piece. One strategy for farmers to reduce the cost of inputs and increase their bargaining position in the marketplace is to form Farmer Producer Organisations (FPOs).

Introduction

India is the largest banana producer in the world. They grow bananas on an area of 9 million hectares and get 36 MT per hectare. India exported 2,000,000 MT of banana worth $1 billion to other nations. The banana production system supports the labour market, alternative food system, export eco-system, and nutritional security, among other things. The development of climate-resilient banana varieties, tissue culture protocols, macro-propagation, ornamental bananas, micronutrient mixtures, site-specific nutrient management, biocontrol agents for pest and disease control, robust virus diagnostic kits, and so on are all highly recommended and encouraged to make the banana industry sustainable and profitable in the long run. Technologies and products for use after harvest are also vital. Branding, supporting entrepreneurship via incubation platforms, marketing intelligence, and handholding for technical support are necessary to sustain banana production and drive value addition. Bananas and plantains, more than any other fruit or vegetable, constitute a staple food for millions of people worldwide and contribute to a healthy diet. In addition to carbohydrates, it's a wonderful source of potassium, vitamins, and minerals. The fat-free fruit has a calorie count of 90 per 100 grams. Dessert bananas are normally eaten raw, while plantains or cooking bananas are commonly prepared in a variety of savoury ways, such as boiling, steaming, frying, or roasting. The banana industry has expanded in recent years, making a greater contribution to the economy in terms of both employment and food supply.

Aluminium is a ubiquitous metal and seen in an environment. Source of aluminium happens through dietary souce, food addivitives, packing materials, medications, environmental exposure as well as occupational exposure. Toxico kinetics is related to the interaction of aluminium with biological systems and toxicity also. Toxico dynamics of aluminium is related to the the oxidatve stress, neuro toxicity and bone toxicity. Diagnosis is based on MRI scan and measurement of serum as well as urine. Treatment is dependent on chelation therapy as well as avoidance of exposure. Finally it is concluded that aluminium toxicity leads to health risks in a significant manner along with potential adverse effects on neurological, gastro, intestinal, renal as well as skeletal systems.

Introduction

Aluminium is a ubiquitous metal observed naturally in the environment. It is widely used in various industrial and consumer products including cookware antacids, vaccines, and food additives. While aluminium is normally considered safe in low concentrations and exposure to high levels can lead to toxicity causing a range of adverse effects on human health. In this comprehensive article, authors will provide information regarding its toxicokinetics and toxicodynamics, clinical signs and symptoms, associated lesions, diagnosis and treatment strategies.

Cadmium, a roxic heavy metal, poses risk in a significant manner especially to human health and the environment. It's wide spread industrial use and presence in various products make exposure a concern particularly for both environmental and occupational settings. Understanding the source, toxico dynamics, toxico kinetics, clinical manifestations, diagnosis as well as treatment of cadmium poisoning is critical in mitigating it's adverse effects especially on human health. Cadmium gains an entry into the environment through natural processes namely volcanic activity as well as weathering of rocks. Whatever it may be, human activities along with mining, smelting, refining of metals and manufacturing of batteries, plastics as well as pigments, are major contributors to cadmium release especially into the environment. Additionally, cadmium is seen in tobacco smoke, resulting in exposure among smokers as well as passive smokers. Once released into the environment, cadmium gains entry into the human body through many routes such as inhalation, ingestion and dermal contact An inhalation of cadmium containing dust or fumes is a prominent route of exposure in an occupational settings especially in industries namely mining, smelting as well as welding. The consumption of contaminated water and food is another general route of exposure especially for the general population. After consumption, cadmium in essential manner accumulates especially in the kidneys as well as liver with a half life of approximately 10 - 30 years in the organs. It also accumulates particularly in bones, where it consists of half life of several decades.

i) Silicon Technology

Silicon technology in agriculture refers to the use of silicon-based compounds, primarily silicon dioxide (SiO2 ), in pesticide formulations and as part of integrated pest management (IPM) strategies. Silicon technology is not a pesticide itself but is used to enhance the effectiveness of pesticides and contribute to sustainable pest management. Here are some ways silicon technology is applied in pesticide use:

1. Silicon-Based Adjuvants: Silicon-based adjuvants are added to pesticide formulations to improve their efficacy. These adjuvants can enhance the spreading, wetting, and sticking properties of pesticides, ensuring better coverage of plant surfaces and improving the retention of the active ingredient. This leads to more effective pest control and reduces the need for higher pesticide concentrations.

2. Induced Resistance: Silicon has been shown to induce plant resistance against pests. When plants take up silicon from the soil and deposit it in their cell walls, it can create physical barriers that make it more difficult for pests to penetrate plant tissues. Additionally, silicon can trigger the production of defensive compounds in plants, making them less susceptible to pest damage.

3. pH Buffering: Silicon compounds can act as pH buffers in pesticide formulations, helping to maintain the stability and efficacy of the active ingredients over a broader pH range. This can be particularly useful when mixing pesticides with other chemicals or using them in different environmental conditions.

Since bees are indicator species, their abundance on earth serves as a barometer for environmental conditions and the health of ecosystems. With up to 60,000 honey bees living in a single hive, each with a distinct job, the life of a bee is undoubtedly one of nature’s greatest miracles. There is much to be learnt from the exquisitely smart, well-organized lives of bees. Around the world, honey bee hives have been experiencing severe decreases over the past ten years, and local pollinating species are also experiencing significant losses. A growing number of studies point to a particular class of pesticides as the principal cause of the worldwide pollinator disaster, and if our government agencies and certain legislators don’t act quickly, the pollinator situation will only get worse.

Rachel Carson written Silent Spring 50 years ago, she expressed her concerns about the use of systemic insecticides like neonicotinoids. We are currently seeing f irst-hand how her forecasts come true

“The world of systemic insecticides is a weird world, surpassing the imaginings of the brothers Grimm… It is a world where the enchanted forest of the fairy tales has become the poisonous forest in which an insect that chews a leaf or sucks the sap of a plant is doomed. It is a world where a flea bites a dog, and dies because the dog’s blood has been made poisonous, where an insect may die from vapors emanating from a plant it has never touched, where a bee may carry poisonous nectar back to its hive and presently produce poisonous honey (Rachel Caron, Silent Spring)”.

Introduction

Emerging and reemerging infectiousdiseases are defined as the diseases of which the incidence has shown an increasing trend in the recent past or threatening to increase in the near future. Emerging infectious disease (EID) are caused by apathogen previously unknown to cause disease orre-emerging pathogens, which have previously causeddisease but now reveal increased infectivity orextended transmission ranges that improve their ability to cause disease in human populations. Today, whole world is facing a concerning rise in emerging infectious diseases and the majority of EID have been observed in the past decades.Multiple recent EID outbreaks e.g. the 2003 SARS and the 2012 MERS outbreaks, the 2009 swine flu pandemic,the 2013–2016 Ebolavirus epidemic, the 2014chikungunya outbreak in the Western Hemisphere,the 2015 Zika and the 2019 SARS Cov 2 virus epidemic have exhibited significantmorbidity and mortality and large geographicranges. These outbreakshave indicated the potential for evenmore severe outcomes in future outbreaks. Severaladditional pathogens are also considered capable ofproducing EID outbreaks, these include Escherichia coliO157:H7, hantavirus, dengue virus and West Nilevirus, while malaria, tuberculosis (TB), cholera, andinfluenza are often considered reemerging diseases with the potential for new outbreaks.Many newly emerging diseases in humans are actually long-standing zoonosesof animal host species that appeared inhuman populations following a climatic or environmental change. The complex interplay between climate change, ecosystems, and human activities have created conditions that favour the emergence and spread of infectious diseases posing significant challenges to public health. Although, improved sanitation, increased access to health care, and advances in preventive and clinical medicine have reduced the mortality and morbidity rates of several infectious diseases.

Introduction

The classic bone tissue engineering paradigm highlights several key players: biocompatible scaffold that closely mimics the natural bone extracellular matrix niche, osteogenic cells to lay down the bone tissue matrix, morphogenic signals that help to direct the cells to the phenotypically desirable type, and sufficient vascularization to meet the growing tissue nutrient supply and clearance needs. The biomaterials are critical components in the bone-tissue engineering strategies, including polymers, ceramics, or their combinations applied in various forms, such as membranes and three-dimensional (3D) scaffolds. These materials typically mimic the extracellular matrix of bone tissue during the tissue regeneration process, providing mechanical support and a suitable environment for cell attachment, proliferation, and differentiation

Introduction

Climate change specifies long-term shifts in weather patterns, which are measured over decades to millions of years. In modern times, it predominantly concerns the increase in Earth’s average temperature due to human activities, particularly the burning of fossil fuels10. The rise in greenhouse gases such as carbon dioxide, methane, and nitrous oxide traps heat in the atmosphere, leading to global warming. In connection with animal health, climate change affects the ecosystems in which animals live, influencing the availability of water and food, the spread of diseases, and the physiological stress animals endure due to temperature extremes. Domestic animals, mostly livestock, are vulnerable to heat stress and reduced productivity, whereas wildlife faces altered habitats and increased exposure to pathogens. The connection between climate change and animal health is intricate, as changes in temperature, humidity, and weather patterns create new challenges for both domestic and wild species.

Introduction

In poultry, the intestine is home to trillions of microorganisms, with bacterial concentrations reaching up to 10¹² bacteria per gram of digesta. In a healthy digestive system, this microbial community is highly diverse and metabolically active, supporting crucial functions in digestion, immune defense, and overall health. The gastrointestinal tract (GIT) of a newly hatched chick begins as a sterile environment but quickly develops a complex microbiota as the bird matures. The composition of gut microbiota is highly variable, shaped by environmental factors, diet, the genetic makeup of the host, and other influences. This dynamic microbiome plays a pivotal role in nutrient absorption, disease resistance, and growth efficiency, making it a central focus in poultry health management and productivity enhancement.The health and productivity of poultry are fundamentally influenced by the gut microbiome, which shapes digestion, immunity, and growth potential. Microbial diversity variesacross several poultry species, including broilers raised intensively, native chickens in free-range conditions, and unique species such as Guinea fowl, Kadaknath, and red jungle fowl. Using advanced metagenomicsanalysis of microbial diversity, structure, and function, highlighting the implications of microbiota composition on poultry health and productivity possible. The gut microbiota is increasingly recognized as a major determinant of health and productivity in poultry. It not only influences nutrient absorption and metabolism but also plays a critical role in immune response and pathogen resistance. Intensive farming practices have altered gut microbial ecosystems in commercial broilers, often reducing diversity compared to native breeds and heritage species raised in field conditions.

Introduction

Status of Tuberculosis : Tuberculosis is a complex and multispecies disease since the origin of human civilization. Evidence of tuberculosis (TB) exists in 3000 years old Egyptian mummies and about 17,000 year old fossilized bison (Fareed et al., 2024). Now, every year, 10 million people fall ill with tuberculosis. Out of 10 million people currently with new active TB, 1,40,000 (range, 69,800–235,000) are estimated to be new cases of zTB (1.4%) of which an approximately 11,400 (8.1%, range 4,470-21,600) died (WHO, 2020).Despite being a preventable and curable disease, 1.5 million people die from TB each year – making it the world’s top infectious killer (WHO, 2023). Disease is still in an increasing scenario as evident that in 2018, an estimated 10 million people fell ill with TB and 1.5 million died of the disease whereas in 2021 there were an estimated 10.6 million new cases of TB and 1.6 million TB deaths (Ayalew et al., 2023). COVID-19 has further increased the projection of TB and increased the expected case number. As it is predicted that between 2020-2050, 31.8 million will have died of TB, More than half million cases of TB annually are classified as drug resistant, as a result, TB is becoming more difficult to diagnose and treat.

Introduction

To maintain optimum reproductive status early diagnosis of reproductive problems is important. Various advance diagnostic techniques are available for diagnosis of reproductive problems. Some of them are still in early stages of development or some though available; are not widely used due to various constrains.The various diagnostic techniques used in animal reproduction are ultrasonography, Doppler ultrasonography, endoscopy, laparoscopy, hormonal assays, vaginal cytology, x ray etc.

Accurate history and Thorough examination of reproductive tract

Accurate history is a powerful tool of enormous clinical value. Behavioral problems due to pain or psychological factors can also be ruled out on the basis of adequate history of the patient. Tentative differential diagnosis can be made by taking history of previous breedings.Through digital and vaginiscopic exanimation of reproductive tract helps to rule out anatomical abnormalities, which may interfere with natural mating. It also helps in diagnosis of fertile phase of oestrus cycle. In cases of refusal to mate due to anatomical problems like septum, narrow passage or due to behavioral problems AI can be performed. Vaginoscopic examination aids vaginal cytology in deciding right time of natural service or insemination in proper breeding management or abnormal oestrus cycle.

Introduction

Podocytes are highly specialized cells with a complex structure that plays an important role in kidney physiology. The characteristic feature of these cells is that its cell body has foot processes which interdigitates with the foot processes of another podocytes leaving filtration slits in between them. These filtration slits are bridged by the slit diaphragm which is an extracellular structure. These cells are located on the outer surface of glomerular basement membrane (GBM) and thereby they check the protein loss. The cell body of these cells contain nucleus, golgi apparatus, smooth and rough endoplasmic reticulum, lysosome and mitochondria. Their main function is in establishing the selective permeability of the glomerular f iltration barrier. Several molecules, including nephrin, CD2AP, FAT, ZO-1, P-cadherin, Podocin, and Neph 1-3 have all been shown to be associated with the slit diaphragm (SD) protein complex, and some of these molecules are critical for its integrity. In cases of chronic disease podocytes gets loosen and they separate from the surface of glomerular basement membrane (GBM). Podocyte injury frequently leads to reorganization of the slit diaphragm and reorganization of the foot process structure. Disturbances of podocyte architecture results in retraction of its foot processes which leads to proteinuria. This may be thelater progress into acquired glomerular diseases. The approach to regenerate podocyte and develop a mechanism of podocyte specific drug delivery system by understanding the molecular mechanism of podocyte function appears a promising area for treatment of proteinuric kidney diseases in future.

Introduction

India is primarily an agriculture-based country, with the livestock sector being a vital component of its agricultural landscape. The meat sector plays a crucial role in providing livelihoods and jobs to rural and village populations. Slaughtering food animals not only yields meat but also generates valuable byproducts that can significantly benefit society. Typically, only one-third of an animal’s weight is meat; the remaining two-thirds consist of byproducts and waste, which must be effectively processed and utilized. Efficient utilization of these byproducts directly impacts both the economy and environmental pollution. The yield of animal byproducts can range from 50% to 60% of an animal’s live weight. According to statistics from the Department of Animal Husbandry and Dairying (DAHD, 2019), India saw the slaughter of 11.92 million buffalo, 3.05 million cattle, 50.86 million sheep, 97.19 million goats, 10.73 million pigs, and over 2.81 million poultry birds in 2018-19, resulting in the production of 8.11 million tonnes of meat.

Introduction

In current scenario of COVID-19 pandemic, Agriculture and its allied sectorare the only sector which is contributed positive growth rate due to hard work and total devotion of farmers towards it in both first quarter of the financial year 2022-23. Farmers are the backbone of our country but face different challenges such as scarcity of land due to fragmentation, water sources, impassable roads, unavailability of better financial services and new technologies. Since a decade number of small and marginal farmers keeps on increasing. Due to the fragmented holding of land and improper management practices in farming inadequate access to market, making them agriculture more unviable. Government motive to double the farmers’ income in 2022-23 by addressing the challenges of farm sector. The government affirmed that farmer producer organizations (FPO) are the most appropriate institutional form around which farmers can mobilize and build their capacity to collectively leverage their production and marketing strength. However, majority of these located in rural areas and suffer from the problems like Inadequate Professional Management and Manpower, poor start-up capital, lack of technically skilled man power, ineffective capacity building training programmes. There is a need to find the solution and to need bring policy changes to handle this problem to empower our farmers and Indian economy by farmers produce organisation.

Introduction

Goat farming plays a significant role in supporting rural livelihoods, contributing to food security, and generating income through milk, meat, and fiber production. However, achieving sustainable goat productivity requires scientific management, wherein, nutrition is a critical factor that makes profound effect on overall performance and production. With increasing global demand for goat-derived products, optimizing nutritional strategies has become essential to improve both production efficiency and sustainability. Globally, the sector is shifting from subsistence-oriented backyard farming to more commercialized systems, driven by increasing demand for goat meat and dairy products. India, which ranks first in goat population with 148.88 million goats (DADF, 2019), is experiencing rapid changes as goat farming evolves from a low-input livelihood strategy into a thriving commercial industry (Ramachandran et al., 2019).This transformation is not only economic but also ecological. Goats are known for their remarkable adaptability to harsh environments and climate variability, which makes them crucial in ensuring food security under changing environmental conditions. Their ability to utilize marginal lands and convert low-quality forages into meat, milk, and fiber allows them to thrive in regions unsuitable for other livestock . Shifting towards semi-intensive and intensive systems, farmers can utilize better breeding, nutrition, and healthcare practices to meet growing market demands.

Introduction

Biofilm formation is a series of complex process and accomplished mainly in five stages -Reversibleattachment, Irreversible attachment or colonization,Proliferation, Maturation &Dispersion. Usually biofilms comprise 10% of dry mass that represent microorganisms while the rest 90%derived from the matrix of biofilm. Microbial biofilms are aggregates of microorganisms embedded in self-produced matrices and adhere to an abiotic or biotic surface. Firstly, Marshall et al. (1971) threw light on the concept of biofilms &it’s complexity was discussed by many researchers. According to Donlan and Costerton (2002) “Biofilm as a structured community of microbial cells enclosed in a self-produced polymeric matrix and adherent to a surface to interface, and to each other” still remains the most appreciated definition of biofilms (Mishra et al., 2022). Basically, microbial biofilms are complex, dynamic and three dimensional heterogeneous structures in which cells are interconnected by EPS (Extracellular Polymeric Substances). Biofilms are found to be resistant against UV light, metal toxicity, antimicrobials and other chemical agents like soaps, detergents, disinfectant and other cleaning agents. Future insight the immense need to implicate effective methods for elimination of biofilms from the environment.

A novel zoonotic disease was reported in December 2019 in Wuhan (China) and patients were presumably exposed to a new coronavirus, designated as SARS CoV-2. This virus probably crossed into humans from an animal species, most likely a bat, spreading rapidly across the world and causing the coronavirus disease 2019 (COVID-19). This infectious illness was responsible for a global pandemic that caused deaths and economic despair (Santaniello et al., 2023). The latest WHO data (December 2023) confirmed 77,38,19,856 cases worldwide since the beginning of this zoonosis and 70,10,568 deaths (WHO, 2023), making this pandemic one of the deadliest in human history. Human CoVs (HCoVs) are often of animal origin but adapt to humans via direct jumping or through intermediate species. These data and the zoonotic origin of SARS-CoV-2 quickly raised questions concerning the potential role that animals could play in transmitting the virus to humans or other species.

Forensic science has traditionally been associated with human criminal investigations, but its application to veterinary cases is gaining momentum. Hair is a specialized outgrowth of epidermis, a component of the skin. Hair is chemically stable especially when compared to other physiological materials such as blood, semen or any other f luid as it is strongly resistant to decomposition and this property makes hair a nearly ideal type for physical evidence. However, the forensic identification of animal hair requires different skill sets and competencies to those required for human hair comparisons (Tridico et al. 2014). Hair carry a lot of biological information, their examination is easy and very cost effective. Recently Funes et al. (2023) has reviewed both macro and micro quantitative methods for human hair analysis.

The study of the animal hair could represent a useful tool in veterinary forensic investigation and thus can be helpful in species identification in veterolegal cases, illegal transport of slaughtered animals, poaching or wildlife crime, fraud in textile and fur industry, traceability of predators and identification of their victims (Dahiya and Yadav 2013). The use of hair analysis in forensic science dates back to the 19th century, with early forensic scientists recognizing its potential in criminal investigations. Over time, techniques have evolved from simple visual comparisons to sophisticated microscopic and biochemical analyses.

GPCRs are integral membrane proteins that contain seven transmembrane (TM) α-helices, with a short cytoplasmic Helix 8 interconnected to the TM7 and the cytoplasmic C terminal. The amino terminal is extracellularly disposed.

The 7 TM helices are interconnected by 3 extracellular and 3 intracellular loops. On the extracellular side between TM3 and TM4 is located a conserved disulphide bond. GPCRs being allosteric proteins, agonist binding at one site that is accessed from the extracellular space and termed the orthosteric site, promotes allosteric binding to another partner, a heterotrimeric G protein at the cytoplasmic side. Agonist binding not only promotes binding of the receptor to a G protein, but the affinity of the agonist for the receptor is increased by the G protein.

Food Animals are the main protein source for human nutrition in the world.Sub-therapeutic doses of antibiotics are commonly used in food animal production, through their addition in feed and wateras antibiotic growth promoters (AGPs). Animal production is considered one of the main sources of antimicrobial resistances (AMR), thus the research for alternative strategies to the use of antibiotics in animal diet is essential to f ight the emergence of AMR. Currently, AMR causes the death of 700,000 people per year and it is forecasted that this will increase exponentially to 10 million by 2050, becoming the main cause of death worldwide.The reduction of antimicrobial resistance is a major challenge for the scientific community. In a few decades, infections by resistant bacteria are forecasted to be the main cause of death in the world. The withdrawal of antibiotics as growth promoters and their preventive use in animal production is essential to avoid these resistances, but this may impair productivity and health due to the increase in gut inflammation. The best alternative to Antibiotic growth promoters (AGPs) is a general improvement of conditions for food animals. In order to start a reformation of the Food Animal Industry as a whole, it’s essential to research to find out effective, resistance rare, low toxic and affordable alternatives to antibiotic growth promoters. Culinary herbs derived bioactives may be the promising products to address this challenge because it is traditionally proven to restore the gastrointestinal health due to beneficial effects on microbiota composition, mucosal barrier integrity, and immune system to control inflammation.

Herbal medicines have become popular these days as complementary therapies for various disorders. These are available as single compounds, enriched extracts, or polyherbal preparations. The polyherbal formulations behave very differently as compared to the single compounds due to the interaction of different chemical constituents, present therein, with multiple receptors/targets in the biological system. The presence of the multiple chemical constituents is also likely to exhibit pharmacokinetic and metabolic interactions. Thus, it becomes difficult to monitor and predict the exact pharmacokinetic profile of all the chemical constituentspresent in a polyherbal formulation (He et al. 2011; Xie et al. 2012). As a result, pharmacokinetic studies of polyherbal formulations have been a long-standing hurdlein phytotherapy research. Conventional scientific approach for studying thepharmacological behaviour of a multicomponent therapy is to isolate the individualcompound and study the effect of these compounds on various targets and enzymes, independently. To rationalize the use of herbal medicines,a clear understanding of their pharmacokinetics and metabolism in the physiologicalsystem is required. A fundamental knowledge of pharmacokinetics of phytopharmaceuticals will be helpful inauthenticating their use.