eChapters

3.1. History and Development of Plant Classification
The botanical term “Angiosperm”, from the Ancient Greek ‘angeíon’ (receptacle, vessel) and seed, was coined in the form Angiospermae by Paul Hermann in 1690, as the name of that one of his primary divisions of the plant
kingdom.
This included flowering plants possessing seeds enclosed in capsules, distinguished from his Gymnospermae, or flowering plants with achenial or schizocarpic fruits, the whole fruit or each of its pieces being here regarded as a seed and naked.
Its use with any approach to its modern scope only became possible after 1827, when Robert Brown established the existence of truly naked ovules in the Cycadeae and Coniferae, and applied to them the name gymnosperms. From that time onwards, so long as these Gymnosperms were, as was usual, reckoned as dicotyledonous flowering plants, the term Angiosperm was used antithetically by botanical writers, with varying scope, as a group-name for other dicotyledonous plants.
In 1851, Hofmeister discovered the changes occurring in the embryo-sac of flowering plants, and determined the correct relationships of these to the Cryptogamia

The word chicken originated from old English word ‘icen’, Germanic word ‘kivkenam’ and cock (‘keuk’). According to Charles Darwin, the original chicken (Gallus domesticus) from which all modern domestic breeds of chicken have descended is referred to as Red Jungle Fowl (Gallus gallus). Archaeological discoveries in the Indus Valley suggest that chickens were probably domesticated from the Red Jungle fowl (Gallus gallus) as early as 5400 B.C. (West and Zhou, 1988). But there are some others who believe that modern chickens have been contributed by four wild species found in South East Asia. These were Gallus gallus (Red jungle fowl) found in eastern part of India, Burma, Java and Sumatra, Gallus sonneratii (Grey jungle fowl) prevalent in western and southern parts of India, Gallus lafayetti (Ceylone
jungle fowl) the native of Sri Lanka and Gallus varius (Javan jungle fowl) found in lower adjacent islands of Java.
2.1. Origin of Modern Poultry
• 8000 BC
Archaeological evidence suggests that chicken existed in China
• 5400 BC
China - Cishan culture; but contribution of these birds to modern birds are doubtful.
• 3000 BC
In India account of cock fighting indicate that chicken have been part of the culture for a long time.

Abstract

The knowledge of programming language(s) is necessary to solve biocomputational problems and also understand the data pattern. Computer programming is used to develop software to extract information from data which is very crucial while practicing bioinformatics. Programming language is a man-made, computer-understandable, artificial language, that is designed to instruct a machine, particularly a computer to get the desired output. This chapter briefly narrates the concept of algorithms, programming languages, and the historical perspective of the same.

Rabbits belong to the mammalian order Lagomorpha, which includes rabbits, hares, and Pikas. Fossil records indicate that Lagomorpha originated in Asia over 40 million years ago during the Eocene period. The continental drift during this period likely contributed to the diverse distribution of rabbit and hare species worldwide, excluding Australia. There are over 60 recognized breeds of domestic rabbits in Europe and America, all descended from the European rabbit (Oryctolagus cuniculus), the only widely domesticated rabbit species. This species is distinct from native rabbits like North American jackrabbits and cottontail rabbits, as well as all hare species.

Nowhere in the plant kingdom do ecology, evolution, and human affairs come together as intricately as phenomena involving secondary metabolites. The importance of these compounds is apparent in some of the earliest annals of human history. For example, Papaver somniferum, the original source of morphine and codeine, was known to the Sumerians in 4000 B.C. as hul gil (joy-plant). These two alkaloids, so important in human affairs for many years, probably evolved within the genus Papaver originally as protective compounds against herbivores. As a testament to the importance of secondary metabolites,

P. somniferum was one the first plants to be cultivated for a reason other than its caloric or nutritive value. Sadly, its importance has only increased over the time. Organic chemists of the nineteenth century were among the first to recognize and study the diversity of plant secondary metabolites and to analyze them both in terms of structure and function. The German organic chemists developed techniques to acetylate morphine and produce what they claimed at the time to be a non addictive version of the drug. However, acetylation product of morphine trade name Heroin, was vastly more addictive. The economies of several developing nations in Asia still depend on the acetylation of this plant secondary metabolite, and tens of thousands of lives each year are destroyed by its commercial importance. In another striking example of profitable secondary metabolites, acetylation techniques to salicylic acid, derived originally from the bark of willows, Salix, to create aspirin. The modern appreciation of these secondary metabolites from ecological and evolutionary perspectives had its spread outside of the plant-insect ecology community. The overwhelming array of chemicals found in plants was more than simply by-products of primary metabolism that served as waste products for these organisms that lacked excretory systems.

Ecologists and evolutionary biologists soon took up the cudgels, and the past 60 years have seen the development, testing, refinement, and, in some cases, rejection of models that describe the ecology and evolution of these “secondary” substances. With the functional roles of these compounds broadly acknowledged, several challenges presented themselves to scientists interested in their ecological and evolutionary dynamics. Most obviously, the details of the processes underlying the interactions between each of these compounds and their target pest or pathogen became one of the most vibrant topics in ecological and physiological research.

History and development of seed Industry in India can be discussed under two heads

1. Pre-independence development.
2. Post-independence development.

The paper deals with the historical perspective of the tsunamis, much widely discussed Kumari Kandam and Lemuria continent and the palaeo-time series changes on the past continents and oceans, disastrous tsunamis since 16^th century and archeological evidences indicating shore line changes along Tamil Nadu coast.

Keywords: Ancient tsunamis in history, Kumari Kandam and Lemuria, Past shore line changes.

INTRODUCTION

A tsunami is a natural phenomenon consisting of a series of waves generated when water in a lake or the sea is rapidly displaced on a massive scale. Earthquakes, landslides, volcanic eruptions and large meteorite impacts all have the potential to generate a tsunami. The effects of a tsunami can range from unnoticeable phenomenon to large scale devastation.

The term “tsunami” is derived from the Japanese language meaning harbour (“tsu”) and wave (“nami”). The term was coined by fishermen who returned to port to find the area surrounding the harbour devastated, although they had not been aware of any wave on the high seas. A tsunami is not a sub-surface event in the deep ocean; it simply has a much smaller amplitude (wave heights) offshore, and a very long wavelength (often hundreds of kilometers long), which is why they generally pass unnoticed at sea, forming only a passing “hump” in the ocean.

Tsunamis were historically referred to as tidal waves because when they approach land they take on the characteristics of a violent onrushing tide rather than the sort of cresting waves that are formed by wind action upon the ocean (with which people are more familiar). However, since they are not actually related to tides the term is considered misleading and its usage is discouraged by oceanographers.

History and History Taking History in medical/ veterinary terminology is a record of information about the health, illness (past and present), diet, feeding, management,preventive health schedules (vaccination,deworming, dipping, sprays) and hygiene etc. History taking and physical examination is the important step in making a correct diagnosis as it provides valuable information to determine the cause of clinical manifestations. The main purpose of taking history is to get detailed information about the animal, its activities, behavior, diet, health care practices, nutritional status, housing, development of abnormal signs and treatment given, if any. The animal may be cared by owner himself or by an attendant. In the event of animal care given by an attendant, information obtained from the attendant may not be complete and fully reliable as sometimes attendant may not provide correct events and complete picture to hide his mistakes. For obtaining right information a good rapport is to be made with the owner or the attendant. A complete history not only suggest diagnostic possibilities but can also suggest diagnostic probabilities. For example a calf or heifer is unlikely to have Johne’s disease or an adult cow is more likely to suffer from parturient paresis than a first calf heifer. History can also provide a lead for further examination or which system is to be paid special attention.

Making a correct and an early diagnosis is very much important for undertaking rational and effective treatment for fast recovery, avoiding unnecessary medication, reducing the load of so many drugs on body metabolism, reducing environmental pollution and the cost of treatment. There are four important pillars for making a correct diagnosis viz. the history, the systematic clinical examination, the correct clinical diagnostic techniques and the laboratory support. History Taking Clinician’s first step in making a diagnosis is through asking the owner’s complaint. Accurate and complete history may be obtained from focusing on the details of the patient (name, number, species, breed, age, sex and weight), vaccination status, deworming schedule, nutritional history, past and present medical history and environmental history.

History and thorough physical examination is crucial procedures in making diagnosis in horses. Mental attitude of a horse may help in understanding whether it has a localized problem or is systemically ill. Horse is better approached by its left side, keeping himself/herself next to the shoulder. Examination of the horse should be started in a non-threatening, easy, and quiet way. Generally physical examination starts at the head to prevent possible injury to unfamiliar examiner. Abnormalities in demeanor and mentation can be assessed by watching the horse’s initial response to the environment. The locomotor and neurologic systems are examined by observing the horse’s movements and gait at walk and trot, both on straight line and in turns, and backing. Horse weight should be taken. General inspection of the horse should be conducted by standing back keeping a safe distance and looking at the horse for it condition, abdominal shape, muscle symmetry,

Small ruminants are grazing mammals and this group consists of sheep (Ovis aries) and goats (Capra hircus).Advantage of these animals is their low cost, small size and marginal land use, which convert into high quality animal products. Sheep is a grazing animal and goat is a browsing animal. They are generally kept in flock. Therefore flock management is more important than the individual animal. Though, procedure of history taking and physical examination is almost similar to other animals, some peculiarities warrant a separate discussion. Sheep The general methods of history taking and physical examination of sheep are similar to cattle and goat starting from owner’s complaint (history), signalment of the patient, history of the ailing

Aromatic plants synthesise and preserve a variety of biochemical products, many of which are extractable and useful as chemical feed stocks or as raw materials for various scientific investigations. Many secondary metabolites of plants are commercially important and find use in a number of perfumery, flavouring and pharmaceutical compounds. The characteristic property of the plant is due to a variety of complex chemical compounds and hence aromatic plants are generally referred to as ‘natural bio-chemical factories’ or ‘chemical goldmines’.  Not all these natural chemicals can be synthesised in laboratory. Aromatic plants possess odorous volatile substances, which occur as essential oil, green exudate, balsam and oleoresin in one or more parts, namely, root, wood, stem, foliage, flower and fruit.  The term essential oil is concomitant to fragrance or perfumes because these fragrances are oily in nature and they represent the essence or active constituents of plants. They are called volatile or ethereal oils as they evaporate when exposed to air at ordinary temperatures.

Dogs, Cats and birds are pet animals.

Chromosome number of dogs-78

Good Angora breed yield wool of 2-2 ½ “ an average. On record, 8” of wool is also obtained.

Among angiosperms, there are about 18 families which have more than 30 genera which produce tubers. Most genera have many species which are tuberizing, most of which are unknown to man even now. The history, origin and distribution of only a few species which are economically important root and tuber crops and which are commonly used by men for edible as well as medicinal purpose are elucidated in this chapter.

1. Sweet Potato

Exact centre of origin of sweet potato (Ipomoea batatas), and the routes and times for its dispersal to some of its present locations, are still in dispute and are likely to remain so until further archaeological or ethnobotanical evidence is available (O’Brien, 1972).

Bakery Industry

Baked goods have been around for thousands of years. The art of baking was developed early during the Roman Empire. It was a highly famous art as Roman citizens loved baked goods and demanded for them frequently for important occasions such as feasts and weddings etc. Due to the fame and desire that the art of baking received, around 300 BC, baking was introduced as an occupation and respectable profession for Romans. The bakers began to prepare bread at home in an oven, using mills to grind grain into the flour for their breads. The oncoming demand for baked goods vigorously continued and the first bakers’ guild was established in 168 BC in Rome. This drastic appeal for baked goods promoted baking all throughout Europe and expanded into the eastern parts of Asia. Bakers started baking breads and goods at home and selling them out on the streets.

This trend became common and soon, baked products were getting sold in streets of Rome, Germany, London and many more. This resulted in a system of delivering the goods to households, as the demand for baked breads and goods significantly increased. This provoked the bakers to establish a place where people could purchase baked goods for themselves. Therefore, in Paris, the first open-air bakery of baked goods was developed and since then, bakeries became a common place to purchase delicious goods and get together around the world. By the colonial era, bakeries were commonly viewed as places to gather and socialize.^[2] World War II directly affected bread industries in the UK. Baking schools closed during this time so when the war did eventually end there was an absence of skilled bakers. This resulted in new methods being developed to satisfy the world’s desire for bread. Methods like: adding chemicals to dough, premixes and specialized machinery. Unfortunately these old methods of baking were almost completely eradicated when these new methods were introduced and became industrialized. The old methods were seen as unnecessary and financially unsound, during this period there were not many traditional bakeries left.

Bakery is a traditional activity and occupies an important place in food processing industry. The bakery manufacturers in India can be differentiated into the three broad segments of bread, biscuits and cake. About 1.3 million tonnes of the bakery products industry in India is in the organized sector out of 3 millions tonnes, while the balance comprises of unorganized, small-scale local manufacturers. Though, there are sufficient automatic and semi-automatic bread as well as biscuit manufacturing units in India but there are still number of people prefer fresh bread and other products from the local bakery. After entry of Pizza and Burgers’ MNCs in the country, people are changing their tastes also. Today, they are not restricted to bread, cake and biscuits but to other bakery products also. The consumers are increasingly going for newer options with respect to bakery products. With the ventures of few Companies like Britannia, Biskfarm, and Morish etc. competition has increased. Also, the Indian market is witnessing the proliferation of bakery cafe chains in the form of Baristacafe, coffee day, Café Coffee & Monginis etc.

Armed with better technology, know-how and novel ideas, these foreign companies have made rapid inroads into the lucrative market within a very short span of time. Though the demand for bakery products in India has always been on the rise, there is clearly a lack of awareness and the will to break new ground, which has helped global players to gain brownie points while exploring the market in India. The unorganized sector accounts for about half of the total biscuit production estimated at 1.5 million tonnes. It also accounts for 85 per cent of the total bread production and around 90 per cent of the other bakery products estimated at 0.6 million tonnes. The last includes pastries, cakes, buns, rusks and others.

History

Pineapple was discovered a little later in time than expected. It had been a staple of the American diet for years before Christopher Columbus, an Italian explorer, discovered it on November 4, 1493. (www.library.ucf.edu; www. levins.com). That’s when the Guadeloupe Island natives served him and his colleagues this delectable fruit, pineapple. The varieties cultivated at the time were all seedless, and many typical wild cultivars were missing (Collins, 1948), demonstrating the area’s early vegetation. He brought the fruit to Europe. The European travellers were so fascinated by this fruit that they frequently mentioned it in their accounts (Morrison, 1963; Collins, 1960).

It was known as ‘nanas’ or ‘ananas’ by the people of South America (‘ananas’ meant ‘excellent fruit’ in Guarani). People in the area literally cultivated it according to a strict protocol, and they were especially keen to select superior varieties in order to increase fruit yield and quality. They gained a thorough understanding of crop agronomy and production. They also put into practise some of the processing standards that are still in use today around the world (holidayandtraveleurope.blogspot.in). Pineapple wine was made, fibre was extracted, and pharmacological needs such as emmenagogue, abortifacient, antiamoebic, vermifuge, stomach disorders, and poisoning arrow heads were met (Leal and Coppens d’Eeckenbrugge, 1996). In 1980, Antoni and Leal proposed that the pineapple originated in an area further north, between 10° N and S latitudes and 55–75° W longitude, which included parts of north western and eastern Brazil, Columbia, Guyana, and Venezuela. During colonisation, Spanish and Portuguese navigators were instrumental in the distribution and spread of pineapple to all corners of the globe (www.daf.qld.gov.au 2015).

Cashew has a long history as a useful tree but only in the current century, it became an important tropical horticultural crop. Small-scale local exploitation of cashew for its nuts and cashew apples is the pattern for more than 300 years in Asia and Africa. It was not until early years of 20^th century that international trade in cashew kernels began with first exports from India. Although with slow beginning, cashew became an important commercial crop in the last couple of years. In India, use of cashew apples and nuts was started by local people, and accounts from Africa are similar; making cashew wine/liquor possessing a common practice in both Asia and Africa (Johnson, 1973).

Cashew, an evergreen tree, produces both nuts and apples, has become a crop of importance owing to the highly valued kernel and wide adaptability to varying agro-climatic conditions. India is one of the largest producer, exporter and consumer of cashew in the world. Today, cashew has become a crop of high economy and has moved from a crop of waste lands to commercial crop, even in organized sector (Singh, 1998).

The early history of laparoscopy is unknown to many surgeons, but Hippocrates (460-375 BC) in Greece was first to describe endoscopy). He made reference to a rectal speculum. Hippocrates also advised injecting a large quantity of air into the intestines through the anus in the case of intestinal obstruction. He also advocated the insertion of suppository that was 10 digits long. These descriptions suggest that Hippocrates was well aware of ileus with intestinal obstruction and thought of several possible etiologies, including faecal impaction, intussusception, and sigmoid volvulus. Moreover, Hippocrates treated these life-threatening conditions with minimally invasive approaches.

? Dioscorides- Classified Toxicants on the basis of their origin into Plant, Animal, and Mineral Sources.

? Ibn Hazer- Differentiated between a drug or a poison on the basis of matter of dose.

? Dementhes – died by swallowing an unknown poison in his pen.

? Socrates- was poisoned by a cup of Hemlock (Greek State Poison) obtained from Conium maculatum having active principle coniine causes paralysis, coma followed by death.

? Cleopatra- Egyptian lady use strychinine poisoning and she died of Egyptian Asp.

? Lady Toffana- Arsenic containing perfumes known as Aqua Toffana.

The history of the guava fruit can be traced back thousands of years, and it has a rich cultural and botanical significance. The guava fruit (Psidium guajava) is believed to have originated in the tropical regions of Central America, particularly in present-day Mexico and neighboring countries. Archaeological evidence suggests that guavas were cultivated and consumed by the indigenous people of these regions as early as 2000 BCE. From there, the fruit spread to other parts of South and Central America, the Caribbean, and eventually to other tropical and subtropical regions around the world. Guava holds significant cultural importance in various ancient civilizations. In the Mayan culture, guavas were considered sacred and symbolized fertility (Arévalo- Marín et al., 2021). The fruit was also believed to have healing properties, leading to its use in traditional medicine. The Spanish and Portuguese explorers played a pivotal role in spreading guavas to other parts of the world during the Age of Exploration. They brought the fruit back to Europe, Africa, and Asia, where it quickly adapted to the tropical and subtropical climates. Guava cultivation in Asia can be traced back to the 16th century. It is believed that the Portuguese introduced guavas to India and Southeast Asia (Hussain et al., 2021). The fruit’s popularity grew rapidly in these regions due to its adaptability to various soil and climate conditions. Guavas were introduced to Hawaii in the early 19th century. The fruit quickly naturalized and became a prominent part of the Hawaiian diet. Today, Hawaii is known for its delicious pink-fleshed guavas, and guava-based products such as jams and juices are popular exports (Shigeura & Bullock, 1983). Guava has been recognized for its nutritional and medicinal properties since ancient times. It is a rich source of vitamin C, dietary fiber, and various essential nutrients. Traditional medicine in many cultures used guava leaves, fruit, and roots for treating ailments such as diarrhea, dysentery, and respiratory issues. Guava fruit and trees have also found their way into ancient literature and folklore. In some Indian epics and poems, the guava tree is celebrated for its lush greenery and sweet fruits, symbolizing prosperity and abundance (Reguengo et al., 2022).

Hog-plum also known as wild mango (Spondias pinnata), is native to tropical Asia. A small, aromatic deciduous tree, up to 27m height and 2.5m in girth, with a clear bole of 16m, is found wild or cultivated almost throughout India, ascending up to an altitude of 1500m in the Himalayas; also found in the Andamans. Bark thick, aromatic, smooth, grey; leaves imparipinnate, 20-60cm long, leaflets 5-11, 22-28cm long, ovate-oblong, elliptic or elliptic-oblong, more or less oblique with mango-like smell; flowers whitish or greenish white, polygamous, in large, terminal panicles; fruits in terminal clusters of 10-15, drupes yellow-green or rich olive-green, mottled with yellow and black, smooth, ovoid, 4-7cm long; seeds 1-3, one being perfect, oblong-elliptic. Fruit is extremely sour, even when completely ripe.

6.1 Kinetics of Rumen Digestion

The rate and extent of digestion of dry matter or organic matter in the rumen is regarded as the important parameter to predict voluntary feed intake (Khazaal et al., 1993; Blummel,1994). Voluntary feed intake is responsible for more than 50 per cent of the variations in animal response to the diet (Van Soest, 1994) and with low quality unsupplemented roughages, this can be as much as 93% (Blumme1,1994). Therefore, any parameter of feed evaluation that would indicate the voluntary feed intake would be a useful parameter to judge the quality of feedstuff. The rate of digestion of any feed component can be measured by determining extent of digestion at intervals of time. Therefore, the techniques for determining extent of digestion, such as the rumen in vitro techniques (Tilley and Terry, 1963; Goering and Van Soest, 1970) or the in situ Dacron bag technique have been adopted to derive rate of degradation of dry matter of any particular component of the feedstuff. However, unlike in determining the extent of digestion, wherein the incubation is turned off at one particular time (normally 48 hours), measurement of rate of digestion, requires termination of incubation at several points between the start of incubation and until at least 90% of the potentially digestible dry matter is digested (72 or 96 hours). This generates a large number of samples for analysis.

In gas production technique, since gas produced from digestion of substrate is accumulated in the incubations, measurement of gas at different times of incubation would reflect the extent of digestion at different times of incubation. Therefore, unlike with other in vitro / in situ techniques wherein, digestion is determined from the gravimetric disappearance of feed at different times of incubation, gas production technique offers the possibility of using cumulative gas production at different times of incubation to measure the rate of digestion. Thus, a single incubation of feedstuffs is adequate to measure the rate of gas production.

In his classic book ‘The Ascent of Man’, Bronowski has written, “When I was a young man, we all thought that mastery came from man’s domination of his physical environment. Now we have learned that real mastery comes from understanding and moulding the living environment.” Our Biosphere, the living environment that supports us all, has problems and we humans are mainly responsible. We do not live ‘gently’ on the earth. The seven billion of us require air, water, food, energy, housing and amenities and we have developed the earth to provide them and have also created problems. That problems exist are serious is the bad news. That we are recognizing them and that man has shown ability to organize and grow in ascending order from time to time is the good news.
TECHNOLOGICAL OPTIMISTS OR TECHNOLOGICAL CRITICS
A barrier often divides environmentalists and industry. This is the result of a kind of polarization in the 1970s that forced people to define themselves as other technological optimists or technological critics. The environmental debates have usually advocated environmentally benign, small-scale, relatively “low’ technologies. The “soft path” based on conservation and simple renewable energy technologies was pitted against the “hard-path” based on largely on nuclear, fossil fuels etc. In farming Eco agriculture and Organic farming challenged the intensive use of energy, fertilizers, pesticides etc.
WHAT REALLY IS ADVANCED TECHNOLOGY
For the optimistic proponents of advanced technology, the main danger was that retrealist, anti-technology “prophets of doom” would be causing a collective loss of nerve. To them, it would mean missing an opportunity to get an affluent, supercritical society that would overshoot the limits to growth.

Abstract: Hollyhocks are seed propagated garden annuals with numerous hybrid phenotypes, series (single and bicoloured Halo series), Spotlight, Carter’s Double, Double Triumph, Giant Double Powder Puff, Halo Bush (tricoloured), Halo Mixed (eight colours) and cultivars are available in the world market. Unusual plant height, delayed flowering compared to other winter annuals handicap its popularity. While little genetic information and trait heritability has been established for this crop, breeding continues to produce new variants for commercial production. Gene pool of hollyhock exhibits great diversity. Breeding objectives with high priority include dwarf stature (2 feet height), compact growth, double and large flowered inflorescence, precocious flowering and resistance to leaf rust disease.

Abstract

Overall geological histories of the Quaternary deltas of all over the world have been studied considerably, to understand the evolution, eustatic – isostatic changes, land – ocean interactive phenomenon, resources, environment etc. But tectonic signatures of these deltas have been less studied, though these have significance in understanding the natural resources, environment and evaluation of natural disasters. In this context, as the state of Tamil Nadu is a low easterly gradient plain, all the easterly flowing rivers have developed well evolved geomorphic features related to youthful, mature and old stages. Such old stages of the rivers are marked by the spectacular development of deltas. These deltas of Tamil Nadu have been studied in detail for understanding the tectonics with the help of visibly seen tectonic and geomorphic features in satellite based remote sensing and ground based data sets. The study has revealed that the upper age limit / ages of these deltas are probably of Middle to Late Holocene and the various tectonic and geomorphic anomalies observed in these deltas obviously indicate the tectonic processes/ phenomena that prevailed during Middle Holocene - till date. The Proto Cauvery delta of Chennai region is witnessing ongoing NE–SW sinistral, NW–SE dextral and E–W vertical tectonic activities. The streams in Ponnaiyar delta are showing persistent southerly migration due to the probable ongoing land subsidence along NE–SW faults in the southern part of the delta. The Cauvery river which has originally developed a broad bird-foot shaped – arcuate delta, has undergone a phase of anticlockwise rotational migration and stabilized in the northern rim of the delta as Coleroon river during 2300–750 Y.B.P. due to the ongoing tectonic emergence in the south of the delta almost since the last 6000 years or so. The Vellar river, in deltaic regime, shows northerly migration due to E–W grabening in the northern part of the delta. Vaigai and Manimuttar rivers are again migrating northerly in their deltaic regions due to the probable land arching to the south of their present day flow. Thus, the paper discusses the post deltaic / Middle -Late Holocene geological processes of Tamil Nadu deltas which are predominated by tectonic activities.

9.1 Introduction

Holocephalians are a group of highly specialised cartilaginous fishes that live in the sea. It is structurally similar to Elasmobranchii and Teleostomi. It exists in both extinct and living forms. Previously considered a class of Pisces, Nelson (1984) classified Holocephali as a sub-class.

9.2 Systematic Position

Phylum: Chordata

Scientific name: Ocimum sanctum L.
Family: Lamiaceae
The ‘Sacred basil’ or ‘Holy basil’, Ocimum sanctum Linn. a biennial shrub belonging to the family Lamiaceae, is commonly cultivated in gardens. The Hindus of India worship the species and is traditionally grown in courtyards and temples. The aromatic plants belonging to genus Ocimum is popularly known by the name Basil. Basil was derived from Greek word “Basilica” which means royal plant. Among the Ocimum genus Ocimum basilicum is variously known as Sweet basil, French basil or Common basil. Ocimum sanctum is known as sacred basil or Holy basil which is a very sacred plant according to Hindu belief.
Origin and distribution
Ocimum Sanctum has broad distributions, covering the entire Indian subcontinent, ascending up to 1,800 m in the Himalayas and as far as the Andaman and Nicobar Islands. This plant occupies a wide range of habitats.
Botany
Botanically, Ocimum sanctum is an erect, herbaceous, and softly hairy plant that exhibits extensive branching. It typically grows to a height of 30-75 cm. The leaves are entire, serrate, and pubescent on both sides, while the flowers are characterized by their purplish or crimson hue, arranged in racemes. The fruits of Ocimum sanctum are sub-globose or broadly ellipsoid in shape, slightly compressed, nearly smooth, and exhibit a pale brown or reddish coloration with small black markings. It is a biennial or triennial shrub.

I. General information

A kitchen garden/ nutrition garden is a vegetable garden where the vegetable crops are grown in the backyard of a house or any available space in compound or rooftop of the house, to meet the daily requirement of the family. All the members of the family are collectively involved in a kitchen garden.

For a balanced diet, 300 g of vegetables are to be included in our daily food. But on an average, Indians take only 160 g per day. Hence to fill up the gap, vegetable cultivation not only in farmers’ holdings but also in the home gardens is encouraged.

INTRODUCTION
Agroforestry is a land use option that increase livelihood security and reduce vulnerability to climate and environmental change. Agro-forestry has many potential, such as to enhance the overall (biomass) productivity, soil fertility improvement, soil conservation, nutrient cycling, micro-climate improvement, carbon sequestration, bio drainage, bio- energy and biofuel etc. There are many agroforestry systems practiced in India from time immemorial, but the potential of home gardens and their socio-economic significance is very well documented.   Home gardens represent land use systems involving deliberate management of multipurpose trees and shrubs in intimate association with annual and perennial agricultural crops  and livestock within the compounds of individual houses (Fernandes and Nair 1986). Home gardens can also be called as Multitier system or Multitier cropping. Home gardens are highly productive, sustainable and very practicable. Food production is primary function of most home gardens on sustenance basis.

Introduction

Food and nutrition security is the basic requirement of human development. Among the ten global burden of diseases, six are connected with diet related factors. Food and nutrition security is also closely related to other factors like socio economic status, geography and demography. Asia, Latin America and Africa hosts world’s most of the undernourished population. Among these regions South Asia is considered as one of the hotspots of malnutrition, in which India is the major contributor. Fifty seven percent of population cannot afford healthy diet in South Asia.

Over the centuries of remarkable economic growth in India concomitant reduction in under nutrition has not been witnessed and this dilemma is called Indian enigma (Gillespie et al 2012; Sengupta 2019). In India among the different socio economic categories, undernutrition has highly been manifested among SC and STs (Gillespie et al 2012; NNMB 2009).The reasons of food and nutrition insecurity are directly linked to remoteness, dire poverty and dysfunctional food security programmes (Khera 2011; UNICEF 2014). Poor and landless among them are mostly falling prey to chronic food insecurity. Coupled with reduction in locally available dietary inputs, rising food expenditure also compel poor to cut back the quantity and resort to low priced calorie dense food (Smyth & Sweetman; 2010). Therefore, poor people’s diet assume to fraught with starch, which leads to nutritional imbalances and resulting in to various lifestyle diseases like diabetics among them. This situation necessitates the need of local, sustainable household food production through home nutrition gardens. Many studies testify the impact of household level food crop cultivation in addressing malnutrition. Kuhnlein & Raceveur 1996; Pimbert 2009; Vira et al 2015 argues inadequate diets are associated with the “delocalization of food supply” and disruption in existed food systems. Therefore, in general literatures on agriculture and nutrition elicits the positive correlation between cultivating food crops and nutrition security (Gillespie et al 2012; Hossain et al 2016; Viswanathan et al 2015). In this context, home nutrition garden programmeassumes greater significance in countering malnutrition among Paniyan community in Western Ghats region of Wayanad district of Kerala.

ABSTRACT

Homegardens are traditional agroforestry systems present throughout the northeast India especially in foothill region. The high diversity and the intensive care that is given to the homegarden in and around Arunachal Pradesh results in a unique combination of high levels of productivity, stability and sustainability of the system. The homegardens studied here were vertically distributed in four different layers viz, floor, middle, sub-canopy and canopy. Such stratification has given rise to the distribution of a variety of species based on light requirement in the system. Density and diversity index of tree species in the homegardens were highest in Harmutty in the foothills (468.5 plants ha^-1 and 1.17 respectively), whereas lower values were recorded in Ziro in the upper elevation (16 plants ha^-1, 0.651 respectively). Soil nutrients were greater in Harmutty, followed by Doimukh, Nirjuli and then Ziro. Maximum plant detrital (litter and fine roots) biomass and their subsequent decomposition in the homegardens of Harmutty (10185.67 kg ha^-1) might be the probable reason for the efficient nutrient cycling and generation of more available nutrients.

Many human illnesses are contacted from animals and plants; and are also due to imbalance in the environment. Mental, emotional and relational symptoms seen in humans are absent in animals. Nevertheless, careful observations on the behavior of the animal and its relation with others may play key role in homeopathic prescribing in animals. No doubt the use of homeopathy in animals is challenging. Homeopathic treatment of pet animals has many similarities with homeopathic treatment of babies and children such as non verbal communication, the socialization and the relationship with third parties (owners in case of pets and parents in case of children).There are many prescribing strategies in veterinary homeopathy.

Homeopathic Prescription

A basis for homeopathic prescription involves identifying all the aspects of the case (detailed questioning to get the history in respect to animal, its behavior, its nutrition and management, vaccination and deworming status, past and present illness etc.), objective investigations (instrumental and laboratory), coupled with an overview of the picture and dynamics of the patient (it is more philosophical and subjective).

In recording symptoms (both present and past), special attention is to be paid to peculiar symptoms, mental state and generalities. Then appropriate remedy is selected through a process called “reportization”. After selecting an appropriate remedy, its correct potency is determined. Selection of the potency depends on the strength of vital force of the ailing individual, degree and extent of physical pathology and disease chronicity (Hahnemann,1994). Higher potency is selected if vital force is strong. For example higher potency are more suitable for young and growing animals. If tissue pathology is more, lower potency drug is advisable. The effect of higher potency drugs is for greater period of time. Effect of 1M potency may last for a month while that of 30C potency may last for a week. If pathology is not severe, 200C potency may be selected. In case pathology is significant, potency below 200C may be chosen. For weak and emaciated animals, potency 30C or below is advisable. Clear cut cases with strong mental symptoms are right candidates for high potency. Unclear case should be given low potency drug (Pitcairn, 1992). As soon as relief is observed, the drug administration should be stopped. Overmedication is the great error in homeopathic prescribing. In homeopathic prescribing, number of pillules taken in a single dose is less important. What matters is its potency and frequency.

Homeopathy

The word ‘Homeopathy’ is derived from two Greek words “Homeos” and “Pathos” meaning “similar” and “suffering” respectively (Mukherjee and Wahile,2006). This system of medicine is based on the principle of ‘Similars’ propounded by Dr. Samuel Hahnemann in late 17th century. The practice of Homeopathy came into being and gained wide spread popularity too early in the history of medicine at a time when it was impossible to provide any kind of explanation for its clinical efficacy. It is a complete and separate approach to health care using dynamized micro doses of herbs, minerals or animal products to stimulate the body’s innate healing mechanism. Homeopathy is claimed to be more ecological, compassionate and comprehensive owing to use of micro doses. Clinical anecdotal evidence exists to indicate that homeopathy is beneficial in veterinary practice also. The homeopathic remedies stimulate the body defense to heal itself. The practice of homeopathy began first and science in its efficacy is being discovered later as was in case of immunology. An increasing interest is being shown in Homeopathy as a complementary and alternative treatment for both human and animal diseases owing to ever increasing problem of emergence of resistance in micro-organisms to antibiotics, their residues in animal products, and side effects of modern drugs. But critics of homeopathy are not reconciling with the use of highly diluted homeopathic remedies and considering it as a controversial therapy. Researches with the help of modern technology are now illustrating science in homeopathy.

Bengal. Introduction
Homeostasis is unlike any time control process because it involves a very complicated relationship between fundamental knowledge of balance and coordination that ensures existence and performance of all creatures. It is in fact one of the major functioning mechanisms of biological systems, which allows them to sustain stable internal surroundings regardless of outside changes. This regulatory system is essential for evolutionary survival
as well as physiological balance. At the same time, time management-often viewed in terms of human productivity-plays an important part in biology by influencing biological clocks and circadian rhythms. In order to be healthy, behavior and species evolution, physiological processes have to synchronize their daily and seasonal changes caused by environment factors. At first glance, these two concepts seem to be unrelated; but if
viewed from the perspectives of biology and evolution, it becomes clear that they are deeply connected. These include temperature levels, pH values, and glucose concentrations among others that need to be maintained if life has to exist: homeostasis is necessary in order to keep these conditions stable. On the other hand, biological systems rely on time management especially through circadian rhythms so as to schedule diverse activities like feeding, sleeping metabolism or reproduction.This introduction describes how an organism manages to control and regulate its internal processes in conjunction with environmental stimuli is what makes it possible for organisms to live long, and perform productive activities and also enjoy a healthy life.In the year of 1926, Walter Cannon coined the word “homeostasis” with reference to a process through which all organisms maintain stable internal environments regardless changes happening outside their bodies. The theory’s cornerstone was Claude Bernard’s proposition of ‘milieu intérieur’, meaning moderate conditions needed for the existence of an organism itself the basic concept of homeostasis in physiology consists of the complex regulatory mechanisms regulating temperature, glucose metabolism, water balance, pH levels and other systems. Restoring equilibrium
is achieved through perturbations that trigger some reactions from a reference point and mostly these are negative feedback loops for homeostatic processes. For instance, when pancreatic cells secrete insulin into the bloodstream after a meal because there is an incr

Even while the world is ageing, it is not prepared for it. There are 962 million people over 60 in the world as of 2017 with 310.0 million of them living in wealthy countries and 652.2 million in developing ones, according to data from the UN's Department of Economic and Social Affairs (DESA-UN 2017). According to projections, there would be 2.1 billion seniors worldwide by the year 2050 (rich countries: 421.4 million, developing countries: 1670.5 million). By 2030, 80% of the old people in the globe will live in developing countries (DESA-UN, 2015). Elderly individuals in rural developing countries confront challenges such as the lack of pension coverage, work difficulty and high medical costs. Their poor diets and deteriorating poverty raise their risk of chronic illnesses like diabetes, heart disease and cancer (Marshall et al., 2001). 

The homoeopathic materia medica consists of around 1000 drugs, the characteristics of which have been verified or proved. Homoeopathy is unique in that it uses no drug, which has not been proved. The proving has been done by administering pure medicines to healthy human beings and recording in minute detail the effects, mostly adverse, produced by such administration. The tests were conducted on men and women who were mostly medical people and students who were not sick. The drugs were administered in doses consisting of crude drugs or homoeopathic potencies. These volunteers were then asked to describe the effects of the drugs in their own words. These descriptions were noted down by the doctors conducting the experiments and were carefully recorded. Hundreds of thousands of such symptoms were recorded while proving the homoeopathic drugs and the materia medica forms a record of the best proving along with other data collected as a result of laboratory tests and experiments.

In paragraph 25 of the 'Organon of medicine', Dr.Samuel Hahnemann the founder of the system laid down the basis of homoeopathy in the following words: "Now, however, in all careful trials, pure experience, the sole and infallible oracle qi healing art, teaches us that medicine which, in its action on the healthy human body, has demonstrated its power of producing the greatest number of symptoms similar to those observable in the case of disease under treatment, does also, in doses of suitable potency and attenuation, rapidly, radically and permanently remove the totality of the symptoms of this morbid state, that is to say the whole disease present, and change it into health; and that all medicines cure, without exception, those diseases whose symptoms most nearly resemble their own, and leave none of them uncured."

Dr. Samuel Hahnemann laid down the fundamentals of the then new doctrine of homoeopathy in organon of medicine. As observed by him in the 'Introduction⁷ to this work, till then no one had ever taught this homoeopathic mode of cure, no one had carried it out in practice.

Dr. Hahnemann was of the view that the art of the medical practice "should. Rapidly and mildly, effect an unalloyed and permanent cure, and restore to health by means of the smallest doses of a few simple medicines carefully selected according to their proved effect, by the only therapeutic law comfortable to nature, that is Similia Similibus Curentur".

Homoeopathy is based on the following principles:

"The physicians high and only mission is to restore the sick to health, to cure, as it is termed"

The highest ideal of cure is rapid, gentle and permanent restoration of health or removal and annihilation of the disease in its whole extent in the shortest, most reliable and most harmless way on easily comprehensible principles.

Unprejudiced observer of a sick person takes note of nothing in every individuars disease except the changes in the health of the body and of the mind, which can be perceived externally by means of the senses. "All these perceptible signs represent the disease in its whole extent, that is, together they form the true and only conceivable portrait of the disease"

Homoeopathy system of medicine is the system of healing suited to all the young, and the old, the rich and the poor, the people in the developed as well as the underdeveloped countries and for persons in any place or climate. This is not to take away from the value and utility of the other prevalent systems of medicine. The aim of every science of healing is the relief of sick. Every system is successful in its own fashion. Homoeopathy too fights sickness and does so with remarkable results. Additionally the cost of diagnosis in this system is negligible because the diagnosis is by and large symptomatic. The medicine itself is inexpensive. Notable efficacy and low costs are the strong points of homoeopathic medicine. There are no toxic effects of the drugs, no side effects. The time taken for the medicine to show improvement is not long. Homoeopathic medicines are easy to store and have a long life.

Homoeopathy has been attacked again and again on the ground that the potencised drugs cannot be tested in a laboratory. But that way a number of phenomenon is still outside the pale of conventional science. However, laboratory tests have been going in many countries and certain phenomenon not acceptable to conventional scientific beliefs have been observed.

The homoeopathic system of medicine develops for its special use, the inner medicinal powers of the crude substances by means of a process peculiar to it and which has never been tried, whereby they only all become immeasurably and penetratingly efficacious and remedial. Even those that in the crude state give no evidence of the slightest medicinal power on the human body.

This remarkable change in the qualities of natural bodies develops the latent, hidden powers, which influence the body, change the well-being. This is affected by mechanical action upon their smallest particles by means of rubbing and shaking and through the addition of an indifferent substance, dry or fluid. This process is called dynamization; potencizing and the products are dynamizations or potencies in different degrees.

11.1 Introduction
“Homogenization” is the method of mechanical treatment producing a stable emulsion of milk fat and milk serum. Homogenizer is the name given to the equipment employed for this aim. The fat globules in milk range in size from 1 to 20 microns; the average is 4 to 6 microns. The homogenizer reduces the size of the fat globules in milk or cream passing through it. The most of them are less than two microns. After homogenization, no cream line develops on milk; churning homogenized cream cannot generate butter grains. Moreover, milk like cream’s viscosity is changing, which increases the resistance the smaller fat globules face. The increase in viscosity is ascribed to the fact that more milk protein will be deposited on the surfaces of more fat lobules. Homogenizing milk changes its clotting characteristics, so the curd made with rennet or pepsin is supposed to be softer. Because lipolytic enzymes adsorbed on the extra surfaces provided by the more numerous tiny fat globules hydroly fat, homogenized milk or cream may become rancid more quickly than untreated goods. The milk or cream must be pasteurized either right before or right after homogenization to prevent these changes. Usually, the milk is homogenized after main heating and then pasteurized. Driven via a small valve against hard surfaces, heated milk is under pressure of 2500 psi and in a second stage under 500 psi. With a 1/10000 inch diameter, the aperture the liquid is driven through is quite small. Mechanical force milk through a narrow passage at high speed produces homogenized milk. This produces a stabile fat emulsion and breaks down the fat globules in milk into considerably smaller ones. Homogenization reduces the inclination of the fat globules to cluster and merge into cream. Milk is an emulsion whereby fat globules are distributed across a constant skim milk phase. Raw milk left to sit will finally cause the fat to climb to the top and form a cream layer. By means of a small opening under high pressure, homogenization mechanically breaks down the fat globules. While increasing their number and surface area, this lowers the average size of the fat globules. Practically speaking, the net effect is a substantially decreased inclination for creaming of fat globules. Three elements contribute to this increased stability of homogenized milk: a decrease in the mean diameter of the fat globules (a factor in Stokes Law), a decrease in the size distribution of the fat globules (causing the speed of rise to be similar for most globules such that they do not tend to cluster during creaming), and an increase in density of the globules (bring them closer to the continuous phase) owing to the adsorption of a protein membrane. < Heat pasteurization also breaks down the cryo-globulin complex, which often clusters fat globules causing them to increase. The homogenizer consists of a high-pressure pump with an adjustable opening based on a minute orifice. High pressure force of fluids through the orifice causes a notable change in the physical characteristics of the treated product and generates a very intimate combination of the fluid components. Annexure- II has a Homogenizer schematic.

1. Introduction

Raw milk is an emulsion. It is a mixture of milkfat globules, Solid Not Fat (SNF) and water. Over time, milkfat globule separate out from milk serum and comes to the surface of milk as a layer of cream due to the low density of milkfat or due to heating of milk. When milk is heated rapidly and continuously, some of the water in it evaporates from the surface. This exposes proteins and fat molecules, which bind and dry out and forms a skin like film on the surface. 

ABSTRACT

The Cry2A proteins are promising candidates for managing the development of Cry1Ac resistance in insects. The Cry2A class of proteins is different from that of Cry1A, and experiments have shown that insects resistant to Cry1Ac are not cross-resistant to Cry2A proteins. However, the Cry2A proteins are less toxic than Cry1Ac to the polyphagous pest Helicoverpa armigera. Structure-based protein engineering of Cry toxins may pave the way for directed evolution of variants with broad spectrum of insect species specificity, enhanced potency, and stability. In the present study homology modeling of Cry2Ac was done using DeepView software. The template for Cry2Ac protein sequence (accession number X57252) was selected using ExPdb template search. The raw sequence of the Cry2Ac was superimposed over the Cry2Aa PDB template (1I5P). The superimposed model was submitted to the SWISS Model server. After receiving the Cry2Ac model, energy minimization was done using Gromos96. The threading energy and force field energy were calculated. The homology model of Cry2Ac made by us along with the Cry2Ac model from the SWISS-MODEL Repository was used for comparative analysis of receptor binding regions of Cry2Aa. Results showed variation between the two highly homologous Cry2A proteins in their receptor binding regions which may account for differences in spectrum of insecticidal activity.

Abstract

When only sequence data is available, homology modeling has become a useful tool for predicting protein structure. Protein structure is often more important than sequence data when evaluating protein function. Homology modeling, also known as comparative modeling, is based on the principle that two sequences that exhibit a high degree of identity or similarity will also share similar structures. This chapter explores the steps involved in homology modeling, including template selection, alignment, model building, refinement, and validation. The Ramachandran plot is a valuable tool for assessing the conformation and bond angles in a protein model, and we discuss its significance in the context of homology modeling. Ultimately, homology modeling is an effective method for predicting protein structure and has numerous applications in protein engineering, drug discovery, and other fields.

Since bees are indicator species, their abundance on earth serves as a barometer for environmental conditions and the health of ecosystems. With up to 60,000 honey bees living in a single hive, each with a distinct job, the life of a bee is undoubtedly one of nature’s greatest miracles. There is much to be learnt from the exquisitely smart, well-organized lives of bees. Around the world, honey bee hives have been experiencing severe decreases over the past ten years, and local pollinating species are also experiencing significant losses. A growing number of studies point to a particular class of pesticides as the principal cause of the worldwide pollinator disaster, and if our government agencies and certain legislators don’t act quickly, the pollinator situation will only get worse.

Rachel Carson written Silent Spring 50 years ago, she expressed her concerns about the use of systemic insecticides like neonicotinoids. We are currently seeing f irst-hand how her forecasts come true

“The world of systemic insecticides is a weird world, surpassing the imaginings of the brothers Grimm… It is a world where the enchanted forest of the fairy tales has become the poisonous forest in which an insect that chews a leaf or sucks the sap of a plant is doomed. It is a world where a flea bites a dog, and dies because the dog’s blood has been made poisonous, where an insect may die from vapors emanating from a plant it has never touched, where a bee may carry poisonous nectar back to its hive and presently produce poisonous honey (Rachel Caron, Silent Spring)”.

Synonym – Cutaneous ancylostomiasis

Etiology

Hook worm dermatitis is uncommon or rare skin disease due to larval migration of the normal life cycle of Ancylostoma braziliensis and Ancylostoma caninum. It is mainly due to hypersensitive reactions against migrating third stage larvae in the distal extremities.

Introduction

In the perspective of the accelerating national growth rate of 8% recorded at the end of the 10th Plan to a projected growth rate of 10% by the end of the 11th Plan, yielding an average GDP growth rate of about 9% it was appearing that the nation is going to have a strong footing of development. However, it could not be fully achieved due to several reasons including the global recession and other factors related to international economic setback which may deter achieving a projected growth rate of 10% in the 12th Plan. In consideration of the international scenario of growing complicacy in economic growth more emphasis should be given on further efficient utilization of natural resources and intellectual properties of grass root innovators to improve per capita income leading to a promising national structure of economics ensuring wide spread benefits to the society. In this regard, true development of a nation like India can be primarily realized by recognition of wide spread enthusiasm of its innovative human resources living in village and rural areas. It can be made possible only through working with them by appreciating their struggle for survival using all round innovative measures coming out of their daily life experiences and traditional knowledge. Technopreneur Promotion Programme (TePP) is a unique scheme of Government of India for development of society especially by promoting the intellectual properties of grass- root level innovators coming out from the society with a source of inspiration arising out of their daily life struggle for existence. In spite of its limited publicity in remote areas an awareness of this programme has often been found to raise great hope to the villagers to do something for their society exploring the ideas generated from the experiences of life with the help of local resources. Such naturally grown innovation can be found undoubtedly novel and the idea can change their world of dreaming for a more prosperous life by bringing changes in socioeconomic pattern of trade and employment in rural areas with proper support from Government if India through the scheme like TePP.

The number of hormones secreted by the body exhibits control over the physiological regulation of glucose sugar level (homeostasis) in the manner needed by the body. Depending upon the situation, hormones may increase or decrease the level of glucose sugar present in the blood or tissues. The glucose is oxidized to yield energy, carbon dioxide, and water.
Glucose, more than the body’s needs, is stored or converted mainly to glycogen and, to some extent, protein and fat. If glucose is less than the need of the body, its denovo synthesis takes place from amino acids or fatty acids, or is formed from the breakdown of stored glycogen. Various hormones are secreted by multiple endocrine glands to control the blood glucose level. If it fails, it leads to hypoglycemia or hyperglycemia conditions. Gluconeogenesis is not developed at birth in the case of a baby pig. Therefore, hypoglycemia in baby pigs is observed within 2 days of age if starved, leading to hypoglycemia, weakness, confusion, and death.
15.1 The Hormones Involved in Homeostatic Regulation of Blood
Glucose Level
The hormones influencing carbohydrate metabolism are explained below:

Introduction

During transition period and lactation, the high-producing dairy cows undergo a period of extensive tissue catabolism because of negative nutrient balance. Homeorrhetic mechanism at this stage ensures that nutrients are partitioned to favour the growth of fetus prepartum and meet the demand of nutrients in early lactation. Simultaneously the homeostasis secures survival of the animal body functions. However, a decline in feed intake in transition period leads to metabolic disturbances and low milk production in early lactation. The postpartum negative nutrient balance impairs immune and reproductive functions in dairy cows and buffaloes. The increased demand for nutrients and decreased dry matter intake results in low circulating glucose and insulin levels and elevated non-esterified fatty acids (NEFA) and ketone bodies postpartum. The energetic status of a cow or buffalo modulates the secretion of hormones that play key roles in growth of ovarian follicles, ovulation, corpus luteum (CL) formation, and oocyte competence. The NEBAL not only limits milk production potential but also has a detrimental effect on immune cells. Negative nutrient balance is associated with changes in the pattern of ovarian follicle growth and oocyte quality and alteration in endocrines. In addition, cows under negative nutrient balance have extended periods of anovulation. These changes could be minimized by supplementing energy rich supplements like prilled fat or any bypass fat preparations.