eChapter Name: Introduction to Genetics and Biotechnology
9789389992670
eBook Name: HANDBOOK OF GENETICS AND BIOTECHNOLOGY: 2ND REVISED AND EXPANDED ED.
by Rukum S. Tomar
A Overview
Genetics is a branch of biology concerned with heredity and variation.
Genes are the unit of inheritance and are composed of DNA.
The effects of genes are noticeable at the molecular, cellular, family, and population levels.
Genes are DNA sequences that instruct cells to produce particular proteins, which in turn determine traits.
Genes can exist in more than one form and the variants of a gene arise by mutation.
An allele is a variant of a gene that alters its expression in a detectable way. Alleles can be dominant or recessive.
A polymorphism is a particular sequence of DNA that varies in one percent or more of the population.
Single nucleotide polymorphisms are single base pair sites that differ among individuals.
Chromosomes consist of genes and associated proteins.
The human genome consists of 22 pairs of autosomes and one pair of sex chromosomes.
A karyotype is the photographic catalog of the human chromosomes.
Specialized cells and tissues arise by differentiation from the stem cells of the early embryo.
Pedigree diagrams enable recessive and dominant traits to be followed through multiple generations of a family.
A gene pool is the collection of alleles in a population.
Comparative genomics is leading to a more detailed and subtle understanding of evolutionary relationships among species