eChapters

1. Introduction

Antioxidants are defined as molecules which can be safely interact with free radicals and terminate the chain reaction before vital molecules are damaged (Nidhi and Gaurav, 2012). Naturally occurring antioxidants to replace synthetic antioxidants which are being restricted due to their carcinogenicity (Abdel Hameed, 2009). The antioxidant phytochemicals such as polyphenols, flavanoids and related compounds found in medicinal plants have received increasing attention for their potential role in prevention of human diseases (Upadhyay et al., 2010).
 
The genus Ophiorrhiza belongs to the family Rubiaceae and consists of about 150 species and distributed in tropical and subtropical Asia. Species of Ophiorrhiza are economically important and many of these species contain a high value anticancerous compound, a cytotoxic alkaloid camptothecin and other valuable alkaloids. Ophiorrhiza pectinata Arn. is a herbaceous plant and is distributed over peninsular India and Srilanka. A preliminary study conducted in O. pectinata also contains this important alkaloid (0.0040mg/g dry wt). Leaves and stem contain traces of hydrocyanic acid. The main objective of the present study is to evaluate the antioxidant and radical scavenging property of the chloroform methanol and water extract of whole plant of O. pectinata. 

1. Introduction

The therapeutic efficacy of many indigenous plants for various diseases has been described by traditional herbal medicine practitioners (Bharat and Parabia, 2010). Natural products are the source of synthetic and traditional herbal medicine. They are still the primary health care system in some parts of the world (Mahmud et al., 2010). In India, local empirical knowledge about medicinal properties of plants is the basis for their uses as a home remedies. It is generally accepted by many Indians and elsewhere in the world that beneficial medicinal effects can be obtained by ingesting plant products. Plants bear the basis of many traditional medicines throughout the world for thousands of years and continue to provide new remedies to mankind (Patel, 2009). The World Health Organization (WHO) also encourages, recommends and promotes the use of traditional and herbal remedies in the National Health Care Program because these medicines are easily available at low cost, comparatively safe and people have faith in such remedies (Wani, 2007). Herbal medicines are promising choice over modern synthetic drugs. Due to the serious obsession with the modern medicinal system, people have started looking at the ancient healing systems like Ayurveda, Siddha and Unani (Shankar and Ved, 2003).

1. Introduction

Atalantia monophylla (L.) DC. is a small tree belonging to the family Rutaceae; resembles Citrus in general aspects and is considered a close wild relative of Citrus. The species is commonly called as wild lime, in Malayalam it is called as Kattunaragam and in Tamil Katuuelumichai. A. monophylla is used in Ayurveda, Folk and Siddha systems of medicine. It is used for the treatment of rheumatoid pain and glandular swelling (Sankaranarayan et al., 2010). The root is believed to be antispasmodic (Kiritikar and Basu, 1999), the leaves are often applied for itching and other skin complaints (Panda, 2004) and acridone alkaloids isolated from roots were reported to have anti-allergic activity (Chukaew et al., 2008). The chloroform extract of leaves has shown antiviral activity (Chansakaow et al., 1996). Besides its medicinal value A. monophylla leaves are used as flavoring agent, berries are used for making pickles, juice of berries are used for dyeing purpose and wood as timber. It is also useful as a rootstock for breeding new cultivars of Citrus Linn. (Guha Bakshi et al., 1999). This species has high medicinal value and the natural population is under threat due to habitat destruction, use of wood as firewood, collection of fruits for making pickles and harvesting of leaves, roots for medicinal purposes by the local communities. Hence there is a need for developing an appropriate conservation strategy for this species.

1. Introduction

Our Indian traditional medicine depends on herbals which always played an important role in the health problems of many countries. In India, the tribal people are using variety of herbals for effective curing of various ailments. These plants are often used by the local people of that area for treatment of various diseases. Ethnomedicinal studies have offered immense value and opportunities for the development of new drugs. Living close to nature, traditional societies have acquired unique knowledge about the use of wild flora and fauna, most of which are unknown to the people who live away from such natural ecosystem as forests and hills. The hills have been the sources of medicinal plants since the time man realized the preventive and curative properties of plants and started using them for human health care.

Tribal people throughout the world, including India, have developed their own cultures, customs, religious rites, taboos, legends and myths, folk tales, medicine, food, etc., They are the repository of accumulated experience and knowledge of the indigenous vegetation; this can be utilized in tribal development. These days greater emphasis is being laid on this traditional knowledge and on using it in the “bioprospecting” of natural products as a new source of food and medicine.

1. Introduction

Seaweeds are the extraordinary sustainable resources in the marine ecosystem which have been used as a source of food, feed and medicine. The number of natural products isolated from marine organisms increases rapidly, and now exceeds with hundreds of new compounds being discovered every year (Chapman and Chapman. 1980, Cheennubhotla et al., 1986; Chennubhotla et al., 1987; Faulkner, 2002; Proksch and Muller, 2006). Several products of algal origin such as alginate, carrragenean and agar as phycocolliods have been used for decades in medicine and pharmacy (Fitton, 2006). Seaweeds are considered as source of bioactive compounds and produce a great variety of secondary metabolites characterized by a broad spectrum of biological activities.  Seaweeds contain various inorganic and organic substances which can benefit human health (Kuda et al., 2002). The in vitro studies on green, brown and red algae confirmed the following potential activities viz., cytostatic, antiviral, antihelminthic, antifungal and antibacterial (Lindequist and Schweder, 2001; Newman et al., 2003; Dhargalkar and Neelam, 2005; Huang et al., 2005; Gonzalez del Val et al., 2001; Espeche et al., 1984).

1. Introduction

Reactive oxygen species (ROS) is a collective term used for oxygen containing free radicals, depending on their reactivity and oxidizing ability. They participate in a variety of chemical reactions with biomolecule (Kunwar et al.,2011).These free radicals include superoxide anions (O2-), hydroxyl (OH-), peroxyl (ROO), peroxynitrite (ONOO) and nitric oxide (NO) radicals; produced through oxidative process within the body. They can damage both the structure and function of a cell membrane in a chain reaction leading to degenerative disease conditions such as alzheimer, ageing process, cataracts, acute liver toxicity, cardiovascular disease, arteriosclerosis, nephritis, diabetes mellitus, rheumatism, inflammation process and DNA damage that can lead to carcinogenesis (Ghosh et al., 2011).

An antioxidant is a molecule capable of inhibiting or preventing the oxidation of molecules. Antioxidants are substances that may protect cells from the damaging effects of oxygen radicals, highly reactive chemicals that play a part in atherosclerosis, some forms of cancer and reperfusion injuries. Medicinal plants are an important source of antioxidants. The secondary metabolites like phenolics and flavonoids from plants have been reported to be potent free radical scavengers. They are found in all parts of plants such as leaves, fruits, seeds, roots and bark (Chanda and Dave, 2009).

1. Introduction

Nothing in the universe is non medicinal everything has its value in its own way. Infectious diseases are an important health hazard all over the world, both in developing and developed countries. Several synthetic antibiotics are employed in the treatment of infectious and communicable diseases. A number of researchers nowadays are working seriously to find out substitutes for antibiotics as they cause side effects on the functioning of different parts of the body organs and systems. Antibiotics are also known to disturb the natural intestinal micro flora, thus depriving the benefits of these microbes to human body. Medicinal plants exhibit antimicrobial activity since they contain innumerable biologically active chemical constituents. The medicinal plant wealth, the strong and time tested traditional medicare systems like ayurveda and the human resource base are the strengths of India. Over the last forty years intensive efforts have been made to discover clinically useful antibacterial/ antifungal drugs (Sashikumar et al., 2003). Over 50% of all modern clinical drugs are of natural product origin (Ates, 2003). Higher plants as sources of medicinal compounds have continued to play a dominant role in the maintenance of human health since ancient times (Farombi, 2003).

1. Introduction

India throughout its long history has accumulated a prosperous practical acquaintance of the use of medicinal plants for the treatment of various diseases. Chemical studies on Indian medicinal plants make available a priceless material foundation for the discovery and development of new drugs of natural origin. Contrary to the synthetic drugs, antimicrobials of plant origin are not associated with many side effects and have an enormous therapeutic potential to cure many infectious diseases (Bibitha et al., 2002; Maghrani et al., 2005; Doughari, 2006). Plants are used as a medicine in different countries and are a source of many potent and powerful drugs (Kambizi and Afolayan, 2008). Extraction and characterization of several active compounds from these green factories have given birth to some high activity profile drugs (Mandel et al., 2007). Phyllanthus is a medicinally important genus belongs to the family Euphorbiaceae. A number of plants of this family are observed to be beneficial for the treatment of liver ailments. Phyllanthus reticulatus Poir. is a large climbing shrub growing from 8-10 feet in height. It is used in the traditional medicinal system of our country for treatment of a variety of ailments including small pox, syphilis, asthma, diarrhoea, and bleeding from gums (Kirtikar and Basu, 2003;

1. Introduction

Malaria remains one of the most serious tropical diseases and kills an estimated one to two million people each year worldwide (Snow et al., 2005). Spread of drug resistance has played an important role in the occurrence and severity of epidemic diseases in the world (Majori, 2004). As a consequence of resistance to drugs such as quinine, chloroquine, primaquine and mefloquine, the vehemence of malaria has increased in many endemic regions of the world (Schlitzer, 2007; Basco et al., 1994). One of the biggest challenges to malaria control is the emergence and spread of drug resistant P. falciparum strains. Although human malaria transmitted by female Anopheles mosquitoes has four Plasmodium species as its aetiological agents P. falciparum, P. vivax, P. ovaleand P. malariae, the most widespread and severe disease is caused by P. falciparum, which transiently infects the liver before invading red blood cells of the mammalian host. Clinical manifestations occur at the erythrocytic stage and can include fever, chills, prostration and anaemia, as well as delirium, metabolic acidosis, cerebral malaria and multi-organ system failure, which may be followed by coma and death (Fidock et al., 2004; Deprez-Poulain et al., 2005, De Sa et al., 2009).The success of the natural product-based antimalarials such as quinine and artemisinin has showed the importance of plants as potential source of antimalarial agents. Consequently, numerous efforts to identify antiplasmodial activities from plants traditionally used as remedies for fever and malaria (Chen et al., 1997; Havsteen, 2002;

1. Introduction 

Medicinal plants are a basis of huge economic value all over the world. The use of plants and plant products as remedies could be sketched as far back as the beginning of human civilization. The most primitive medicinal use of plants in Hindu culture is mentioned in “Rigveda”, which is believed to have been written between 4500 - 1600 B.C. and is theoretical to be the oldest arsenal of human knowledge (Dhale and Mogle, 2011). Ayurveda is the base of curative science of Hindu culture, in its eight dissection deals with specific properties of drugs and different aspects of science of life and the art of healing (Rastogi and Mehrotra, 2002). Nature has presented on us an affluent botanical wealth and a large number of varied types of plants nurture in different parts of the country. Herbal medicine is still the basis of about 75 - 80% of the whole population. The major part of traditional therapy occupies the use of plant extract and their active components (Akerele, 1993). Secondary metabolites are green medicines present in plants and plant parts that act as defense system against disease inducing organisms or more accurately to protect against disease due to the physiological and biochemical mechanism failure (Alarcon-Aguilar et al., 2002).

1. Introduction

Plants are reliable sources for the treatment of diseases in different parts of the world (Eisenberb et al., 1993; Cowan, 1999; Hostettmann et al., 2000) and they have been unique sources of medicines and constituted the most common use of biodiversity (Hamilton, 2004; Hiremath and Taranath, 2010). Their use contributes significantly to primary healthcare delivery (Holetz et al., 2002) as they are regarded as invaluable sources of pharmaceutical products (Olalde, 2005).

Traditional medicine, with medicinal plants as their most important component, are sold in market places or prescribed by traditional healers in their homes (Von Maydell, 1996). As a result of this strong dependence on plants as medicines, many ethnopharmacological studies have been conducted to determine their safety, efficiency and discovery of new active principles from them. Only, 1,100 plants have so far been thoroughly examined for their medicinal practices in the world (Dobson, 1995).

Herbal medicine have been in use since time immemorial and are still the mainstay mainly in the developing countries because of their better cultural acceptability, better compatibility with the human body and lesser side effects (Kamraj, 2000).

1. Introduction

Gloriosa superba L. (Liliaceae) is a striking tuberous climbing plant with brilliant wavy-edged yellow and red petaled flowers. Glory lilies are grown commercially for a chemical compound, colchicine. The annual foreign exchange through the export of glory lily seeds is estimated to be Rs.100 crores (Alice and Sundravadana, 2012). It is used as anthemirtic, alexiteric and useful in ulcers, piles, abdominal pains and itching. It has abortifacient, anti-pyretic, anti-inflammatory and anti-leprotic properties (Gupta et al., 2005). Leaf blight disease was first noticed in  G.. Superba in West Bengal, India in 2004. The leaf blight disease was observed during June to September. Early symptoms appeared as small, circular to oval, light brownish spots, 2-6 per leaf, scattered at the tip, margin and midrib of the leaves. Subsequently the spots enlarged and usually developed into concentric rings. At an advanced stage, the spots became dark brown to blackish in colour, gradually coalesced and became irregular in shape, then the affected leaf blighted completely. The causal organism was found to be a fungus namely Alternaria alternata (Fr.) Keissler. The pathogen is greatly influenced by weather with the highest disease incidence reported in wet seasons and in areas with relatively high rainfall (Meena et al., 2010). The growth of A. alternata was maximum in pH range of 6-6.5 and temperature range of 25-30°C (Hubballi et al., 2010).

1. Introduction

Medicinal plants are rich source of novel drugs that forms the ingredients in traditional systems of medicine, modern medicines, nutraceuticals, food supplements, folk medicines, pharmaceutical intermediates, bioactive principles and lead compounds in synthetic drugs (Ncube, 2008).  In recent years, antibiotic resistance has become a global concern. This drives the need to screen medicinal plants for novel bioactive compounds as they are biodegradable, safe and have fewer side effects (Prusti et al., 2008). Higher plants, as a source for new potential drugs is still largely unexplored and screening of active agents helps to design the lead molecule later in drug development.

Aegle marmelos(L.) Corr., belongs to the family Rutaceae, and is popularly known as Vilvam tree (Tamil) (Gamble, 1935; Mathew, 1983). It is an indigenous tree found in Iran, India, Myanmar, Pakistan, Bangladesh and most of Southeast Asian countries (Singh, 2009).  A. marmelos has been used from time immemorial in traditional systems of medicine for relieving diarrhoea, dysentery, stomachic, digestive, astringent, peptic ulcer and respiratory infection (Nadkarni, 2000). The fruit, leaves, bark and root are edible and possess medicinal values. The unripe dried fruit used to be astringent, digestive and stomachic, the ripe fruit is aromatic, cooling and is used as laxative.

During the last 21 years, the scientists and scholars of the M.S. Swaminathan Research Foundation (MSSRF) have been working on the design and implementation of projects which could have a large extrapolation domain in respect of imparting a pro-nature, pro-poor, pro-women and pro-sustainable livelihood orientation to technology development and dissemination. I would like to write about a few of the MSSRF initiatives, which have now become state, national and global programmes.

Mahila Kisan Sashaktikaran Pariyojana: Strengthening the role of women in agriculture

MSSRF initiated the Mahila Kisan Sashaktikaran Pariyojana in the Vidarbha region of Maharashtra in 2007 for empowering women farmers, including the widows of farmers who had committed suicide, in areas related to enhancing the productivity, profitability and sustainability of small-scale rain-fed farming. The empowerment measures incorporated access to technology, credit, inputs and market.

Mamata Banerjee has raised the important issue of land use and acquisition for public, political, professional and media debate. With increasing population pressure on land, this issue deserves careful consideration and rational discussion. The Singur dilemma in a wider sense relates to both land use policy and norms of compensation for land acquired by government for non-farm purposes. Land conflicts are also spreading in other parts of our country, as far example where land is needed for establishing Special Economic Zones (SEZs). The Maharashtra Government has wisely adopted the policy of holding a referendum to seek the views of farmers and others who will be dispossessed of their land for meeting the needs of SEZs. Pro-active consultations will help to avoid difficulties later. Water conflicts are also affecting important irrigation projects. Land conflicts are likely to do the same and may affect the balanced growth of the primary, secondary and tertiary sectors of the economy. How can we deal with this situation in a manner which leads to a win-win outcome for all the stakeholders ?

Mahatma Gandhi mentioned to those who wanted to serve rural India that their most useful contribution would be in linking brain with brawn.  Only such a combination of intellect and labour can lead to sustainable advances in the productivity and profitability of agricultural holdings.  West Bengal’s Bidhan Chandra Krishi Vishwavidyalaya (BCKV), almost four decades old, is a fitting example of such work.  It has helped the development of two more universities in the State, namely, West Bengal University of Animal & Fishery Sciences and the Uttar Banga Krishi Viswavidyalaya.  It is important that these three universities function like a consortium of educational institutions mandated to help in achieving agricultural advance, agrarian prosperity and rural transformation in the State.

Livestock and livelihoods are intimately related in our country.  The ownership of livestock is more egalitarian than that of land.  Similarly, West Bengal is full of fish ponds.  It is important that cultivation of crops like rice is done by adopting integrated pest management procedures, so that the water in which fish is cultivated does not get polluted with pesticides.

Livestock and livelihoods are intimately linked in our country.  Mixed farming involving crop-livestock as well as sometimes fish integration has been both a way of life and a means to sustainable livelihoods.  Also, the ownership of the livestock is more egalitarian than that of land.  That is why in our ancient culture, livestock has been given a pride of place in the area of spiritual veneration and natural resources conservation.  Maharashtra is rich in its livestock resources and has also a long coastline with a wide range of living aquatic resources.

The crop-livestock integrated farming system provides an opportunity for promoting organic farming and restoration of soil health, and thereby of an ever-green revolution leading to an enhancement of productivity in perpetuity without associated ecological harm.  It also strengthens household nutrition security.  The country as a whole has over 500 million farm animals.  However, grazing land has been reduced to less than 5 per cent of the arable land area.  Village common property resources, which used to provide fodder and shelter to farm animals, have been overexploited.  Consequently, our farm animal productivity is very low.

India’s Northeast region — one of natural beauty and cultural richness — is both a mega-biodiversity area as well as a “hot-spot” for genetic erosion. The rural population is around 82 per cent and depends largely on agriculture and allied sectors for work and income security. The forests harbour 8000 out of the 15,000 species of flowering plants occurring in the country. Of about 1300 species of orchids reported from India, the Northeast has the highest concentration with about 700 species. The species richness is highest in Arunachal Pradesh where over 5000 flowering plants occur and the lowest in Tripura with 1600 species. Bamboo is the lifeline of the Northeast and 63 out of 136 species found in India occur in this region. Sadly, however, 25 species of bamboo fall under the rare and endangered category. The region is also home to the eri and muga silkworms. The yak and the mithun are unique animals which are threatened by the spread of non-edible invasive species like Lantana, Eupatorium and Mekenia. The cultural diversity of this region is well known, with 225 tribes out of 450 in the country living here. 

Managing the National Food Security System

Rajiv Gandhi understood the wisdom of Gandhiji’s doctrine that Gram Swaraj is the pathway to Purna Swaraj and launched the Panchayati Raj movement. Schedule 11 of Constitution Amendment 73 entrusts panchayats with the responsibility of managing natural resources and fostering sustainable agriculture. Representative democracy through elected members, one third of whom are women, and participatory democracy through Gram Sabhas, are powerful tools for ensuring a pro-nature, pro-poor, pro-women, and pro-livelihood orientation to all rural and agricultural development programmes.
 
The National Commission on Farmers has emphasised the need for community-managed food and water security systems promoted with the help and oversight of Gram Sabhas.  The Gram Sabha can serve as a Pani Panchayat to ensure that rainwater is not only harvested, but is used in a sustainable and equitable manner.

There are reports in financial newspapers that the ongoing (2010) drought affecting nearly 200 districts in the country may not have much effect on GDP, since the farmers in the drought-affected areas contribute hardly 3 per cent to GDP.  It is sad that such a measure of the impact of drought on the lives and livelihoods of millions of rural families is even considered. It is this mindset, typical of the growing insensitivity to human suffering in our country, that is responsible for India being the home for the largest number of undernourished and malnourished children, women and men in the world.  No wonder we are finding it difficult to achieve the first among the UN Millennium Development Goals, namely, reducing hunger and poverty by half by 2015.  Unless we realise that agriculture in India is not just a food- producing machine, but is the backbone of the livelihood of over 60 per cent of our population, rural deprivation and suffering will not only continue to persist, but will get worse, leading to severe social unrest.

How can we develop a sustainable water security system in an era of climate change and global warming ?  In my view, every country should develop a sustainable water security system with the following four major components.

Supply augmentation

The major sources of irrigation water are from rainfall, rivers, tanks, reservoirs and other surface water resources, groundwater, industrial and domestic effluents, and seawater.  Seawater comprises almost 97 per cent of the global water resource and is an important social asset.  With the melting of Arctic and Antarctic ice, sea level will go up with disastrous consequences. The tsunami of December 2004 gave a glimpse of what could happen in the future.  To augment supplies, we must harvest rainwater and store it carefully, both above and below ground.  Also, we should ensure that all waste water which emerges from industry and domestic use is purified and recycled.  Rainwater harvesting should become a way of life, so that it becomes everybody’s business.

A climate-resilient agriculture, which we need urgently, will have to be based on a two-pronged strategy: maximising farm productivity and production during a normal monsoon period, and minimising the adverse impact of unfavourable weather as witnessed during 2009.  Unfortunately, we are yet to develop an anticipatory research and extension programme to minimise damage during unfavourable monsoon periods.  For example, the deficiency in rainfall during the southwest monsoon of 2009 was 23 per cent.  The growth in agriculture and allied sector GDP was minus 0.2.  The highest growth rate in agriculture GDP of 5.2 per cent was observed during 2005-06 when the growth in total GDP was 9.5 per cent.  Had we had a scientific monsoon management strategy, we could have minimised the loss in 2009-10.  Similarly, if we have a strategy for maximising the benefits of a good monsoon, we can hope to achieve at least 5 per cent growth rate during 2010-11 in agriculture and allied sectors.  In parts of China like the Yunnan province, which has experienced 60 per cent less rainfall than normal, there is a move to grow different crops together in the same field, thereby distributing the risk arising from monoculture. It is time to develop a pro-active monsoon management strategy.

The principle of common but differentiated responsibilities is the core of the many climate agreements arrived at so far, including the Kyoto Protocol (1997) and the Bali Plan of Action (2007).  The differentiated responsibilities aim to meet the special needs of developing countries for accelerated and equitable economic development.  Both at Copenhagen and Cancun, the industrialised countries proposed limiting the rise in mean temperature to 2ºC above normal.  Even this seems to be unattainable in the context of the present rate of emission of greenhouse gases (GHG).  Hence, the principle of common but differentiated impact of the 2º change in mean temperature is essential for prioritising climate victims. For example, small islands like Tuvalu in the Pacific Ocean, Maldives, Lakshadweep, and Andaman and Nicobar, as well as the Sunderbans in West Bengal, Kuttanad in Kerala and many other coastal locations will all face the prospect of submergence.  Floods will become more serious and frequent in the Indo-Gangetic plains.  Drought-induced food and water scarcity will become more acute. South Asia, sub-Saharan Africa and the small islands will be the worst victims.  In contrast, countries in the northern latitudes will benefit due to longer growing seasons and higher yields.

In 2009, the world celebrated the 200th anniversary of the life and work of Charles Darwin, a transformational scientist who brought about a revolution in our understanding of evolution.  Evolution through natural selection among living organisms leading to the survival of the fittest was a concept which was alien to Christian thought in Darwin’s time, as faith was strong in the divine creation of the living forms of our planet.  Evolution of higher forms of life, including human beings, from fish and other forms of living organisms was an accepted view in ancient Indian thought, as exemplified by the ten forms of manifestation on earth of the Hindu god Vishnu.

“Variety is the spice of life” is a common saying.  Variation is a must for selection to occur.  Today, we are confronted with the prospect of human-induced changes in climate, leading to adverse variations in temperature, precipitation, flood and sea level.  We will have to be prepared for facing the consequences of drought, flood and coastal storms more frequently.

On the basis of a proposal I had made three years ago, the Food and Agriculture Organisation of the UN (FAO) launched a Global Soil Partnership for Food Security and Climate Change Adaptation and Mitigation at a Multi-stakeholder Conference held in Rome in September 2011. Even with all the advances made in capture and culture fisheries, nearly 90 per cent of human food requirements will have to come from the soil. Land is becoming a diminishing resource for agriculture, inspite of the growing understanding that the future of food security will depend upon the sustainable management of land resources as well as the conservation of prime farm land for agriculture. The National Commission on Farmers emphasised in its report submitted in 2006 the urgent need for replacing the 1894 Land Acquisition Law with a twenty-first century legislation that safeguards the interests of farmers and farming.  Jairam Ramesh is to be complemented for introducing in Parliament a National Land Acquisition and Rehabilitation and Resettlement Bill which pays attention not only to acquisition, but also to the rehabilitation and resettlement of the affected families.

Transgenic varieties combine genes from totally unrelated species. For example, we can now transfer genes for salinity tolerance to rice from mangroves. The recombinant DNA technology is part of the evolution of genetics starting with the rediscovery of Mendel’s Laws of Inheritance in 1900. In the early part of the twentieth century, various techniques like irradiation, use of chemical mutagens and doubling of chromosomes through colchicine treatment were adopted to develop novel genetic combinations.  Today such gene transfer can be done with both precision and ease through recombinant DNA technology. Both molecular marker-assisted breeding and gene transfer now play a very important role in developing genetic combinations to meet the challenges rising from biotic (i.e., pest and diseases) and abiotic (i.e., drought, flood, sea level rise, etc.) stresses. They will gain further importance in the emerging era of climate change. Varieties developed by marker-assisted selection are also eligible for certification under the protocol for products produced through organic farming.

As it is well understood, food and drinking water are the first among the hierarchical needs of a human being. Growing population, expanding ecological footprint, diminishing per capita land and water availability, increasing biotic and abiotic stresses, and, above all, the prospects for adverse changes in temperature, precipitation and sea level as a result of climate change, emphasise the need for keeping issues relating to agriculture high on the professional, political and public agenda. The multiple roles of agriculture in food production, improving nutrition and health, and climate change mitigation are now well recognised scientifically, but are yet be integrated into coherent national policies and strategies. Opportunities for generating synergy among agriculture, nutrition and health are great and this conference is therefore a timely one.

Three years after the establishment of the Central Institute of Fisheries Education (CIFE), a global conference was held at Rio de Janeiro, Brazil, for promoting environmentally sustainable development in all spheres of human activity. At this UN Conference on Environment and Development, generally referred to as the Earth Summit, an Agenda 21 was adopted to provide guidelines for mainstreaming ecology in all major research and development programmes. In Agenda 21, pride of place has been given to the management of aquatic resources from both the quantitative and qualitative aspects. 2012 marks the twentieth anniversary of the Rio conference.  It will be useful to prepare a balance sheet indicating where we have succeeded and where we have failed in implementing Agenda 21 in the area of inland and marine fisheries, as well as integrated coastal zone management.

It was in April-May 1968 that the country witnessed the wonderful spectacle of large arrivals of wheat grain in the mandis of the Punjab like Moga and Khanna. Wheat production in the country rose to nearly 17 million tonnes that year, from the previous best harvest of 12 million tonnes. Indira Gandhi released a special stamp titled “Wheat Revolution” in July 1968, to mark this new phase in our agricultural evolution. The nation rejoiced at our coming out of a “ship to mouth” existence. Later in 1968, Dr. William Gaud of the U.S. referred to the quantum jumps in production brought about by semi-dwarf varieties of wheat and rice as a “Green Revolution.” This term has since come to symbolise a steep rise in productivity and, thereby, of production of major crops.

Wheat production this year may reach a level of 85 million tonnes, in contrast to the 7 million tonnes our farmers harvested at the time of Independence in 1947. I visited several grain mandis in Moga, Khanna, Khananon and other places in the Punjab in April 2011 and experienced concurrently a feeling of ecstasy and agony. It was heart-warming to see the great work done by our farm men and women under difficult circumstances when, often, they had to irrigate the fields at night due to lack of availability of power during the day.

The National Food Security Bill, 2011 designed to make access to food a legal right, is the last chance to convert Gandhiji’s vision of a hunger-free India into reality.

Mahatma Gandhi’s articulation of the role of food in a human being’s life in his speech at Noakhali, now in Bangladesh, in 1946 is the most powerful expression of the importance of making access to food a basic human right.  Gandhiji also wanted that the pathway to ending hunger should be opportunities for everyone to earn their daily bread, since the process of ending hunger should not lead to the erosion of human dignity.  Unfortunately, this message was forgotten after the country became independent in 1947, and government departments started referring to those being provided some form of social support as “beneficiaries”.  The designation “beneficiary” is also being applied to the women and men who toil for 8 hours in sun and rain under the Mahatma Gandhi National Rural Employment Guarantee Programme (MGNREGA).  Sixty-five years after Gandhiji’s Noakhali speech, we find that India is the home for the largest number of under- and malnourished children, women and men in the world.  There are more persons going to bed partially hungry now, than the entire population of India in 1947.

The Food and Agriculture Organisation of the United Nations (FAO) has alerted developing countries about possible steep rises in food prices during 2011, if steps are not taken immediately to significantly increase the production of major food crops. According to FAO, ‘with the pressure on world prices of most commodities not abating, the international community must remain vigilant against further supply shocks in 2011’. World cereal production is likely to contract by 2 per cent and global cereal stocks may decline sharply. The price of sugar has reached a 30-year high, while international prices of wheat have increased by 12 per cent in the first week of December 2010 as compared to their November average.

The quantitative and qualitative dimensions of under- and malnutrition prevailing in our country are well known.  The Steering Committee of a high level panel of experts on food and nutrition set up under my chairmanship to advise the UN Committee on Food Security (CFS) has recently concluded that what we need urgently is a comprehensive, coordinated approach to tackling chronic, hidden and transitory hunger, and not piecemeal approaches.

It was in 1968 that the term Green Revolution was coined by Dr. William Gaud of USA to describe advances in agriculture arising from productivity improvement. Even in 1968, I concluded that if farm ecology and economics go wrong, nothing else will go right in agriculture.  I expressed my views in the following words in my lecture at the Indian Science Congress Session held at Varanasi in January 1968:

Exploitive agriculture offers great dangers if carried out with only an immediate profit or production motive. The emerging exploitive farming community in India should become aware of this. Intensive cultivation of land without conservation of soil fertility and soil structure would lead, ultimately, to the springing up of deserts. Irrigation without arrangements for drainage would result in soils getting alkaline or saline. Indiscriminate use of pesticides, fungicides and herbicides could cause adverse changes in biological balance as well as lead to an increase in the incidence of cancer and other diseases, through the toxic residues present in the grains or other edible parts. Unscientific tapping of underground water will lead to the rapid exhaustion of this wonderful capital resource left to us through ages of natural farming.

Demographic explosion, environment pollution, habitat destruction, enlarging ecological footprint, widespread hunger and unsustainable lifestyles, and potential adverse changes in climate all threaten the future of human food, water, health and livelihood security systems. 2010 appears to mark the beginning of uncertain weather patterns and extreme climate behaviour. Events like temperature rise, drought, flood, coastal storms and rise in sea level are likely to present new challenges to the public, professionals and policy makers. Biodiversity has so far served as the feedstock for sustainable food and health security and can play a similar role in the development of climate-resilient farming and livelihood systems. Biodiversity is also the feedstock for the biotechnology industry. Unfortunately, genetic erosion and species extinction are now occurring at an accelerated pace due to habitat destruction, alien species invasion and spread of agricultural systems characterised by genetic homogeneity. Genetic homogeneity increases genetic vulnerability to biotic and abiotic stresses. To generate widespread interest in biodiversity conservation, the UN General Assembly has declared 2010 as the International Year of Biodiversity.

Biodiversity provides the building blocks for sustainable food, health and livelihood security systems. It is the feedstock for both the biotechnology industry and a climate-resilient farming system. Because of its importance for human well-being and survival, a Convention on Biological Diversity (CBD) was adopted at the UN Conference on Environment and Development held at Rio de Janeiro in 1992. The Convention’s triple goals are conservation, sustainable use, and equitable sharing of benefits. CBD defines biological diversity as follows:

Variability among living organisms from all sources including, inter alia, terrestrial, marine and other aquatic ecosystems and the ecological complexes of which they are part; this includes diversity within species, between species and of ecosystems.

Pranab Mukherjee in his budget speech delivered on 26 February 2010 announced: ‘We are now ready with the draft Food Security Bill which will be placed in the public domain very soon.’  Although no official draft has been placed on the website of the concerned Ministry, several leading organisations and individuals have questioned the adequacy of the steps proposed to be taken under the Bill for achieving the goal of a hunger-free India.  Based on Article 21 of the Constitution, the Supreme Court of India has rightly regarded the right to food as a fundamental requirement for the right to life.  Many steps have been taken since Independence to adopt Mahatma Gandhi’s advice for an antyodaya approach to hunger elimination. In spite of numerous measures and social safety net programmes, the number of undernourished persons has increased from about 210 million in 1990-92 to 252 million in 2004-06.  About half of the world’s under-nourished children are in India.  Also, there has been a general decline in per capita calorie consumption in recent decades.  Grain mountains and hungry millions continue to co-exist.

The President of India, in her address to both Houses of Parliament on 4 June 2009 announced:
 
My Government proposes to enact a new law — the National Food Security Act — that will provide a statutory basis for a framework which assures food security for all. Every family below the poverty line in rural as well as urban areas will be entitled, by law, to 25 kilograms of rice or wheat per month at Rs. 3 per kilogram. This legislation will also be used to bring about broader systemic reform in the public distribution system.

Since then, various arms of government as well as civil society organisations have been working on methods of redeeming this pledge.  The National Advisory Council (NAC) headed by Sonia Gandhi has recently provided a broad framework for achieving the goal of food for all and forever.  The suggestions of NAC include the initiation as soon as possible of special programmes all over the country to insulate from hunger and malnutrition pregnant and nursing mothers, 0-3-years-old infants, street children, destitutes, old and infirm persons, patients suffering from HIV/AIDS, tuberculosis and leprosy, physically or mentally handicapped persons and other disadvantaged citizens.

The goal of food for all can be achieved only through sustained efforts in producing, saving and sharing food grains.

The Supreme Court of India has rendered great service by arousing public, professional and political concern about the co-existence of rotting grain mountains and mounting hungry mouths. In several African countries hunger is increasing because food is either not available in the market, or is too expensive for the poor. Food inflation is showing no signs of abating. In our country, chronic hunger is largely poverty induced. The progress made in achieving the UN Millennium Development Goal No. 1, namely, reducing hunger and poverty by half by the year 2015, has been far from satisfactory and the available data indicate that we may have years and years to go before we achieve this target. Globally, the number of persons going to bed hungry has increased from 800 million in the year 2000 to over one billion. The position is likely to get worse in the near term, since the prices of wheat, rice and maize are going up in the global market. Adverse growing conditions in Russia, Canada and Australia are partly responsible for the recent escalation in grain prices. Nearer home, Pakistan is recovering from serious floods. According to a recent UN report, 3.2 million ha of standing crops and 200,000 heads of livestock have been lost. 

The pros and cons of wheat imports are now a matter of public, political and media concern and debate. I have been quoted as both favouring imports and opposing it. Since this issue is a complex one with short- and long-term implications, I would like to explain my personal position.

The wheat import plan announced by the Government of India is in response to the need for maintaining adequate food stocks both for the purpose of food security and for feeding the public distribution system (PDS). Following the Wheat Revolution in 1968, Indira Gandhi decided to build a sufficient buffer stock of foodgrains under government control in order to ensure that the basic staples are available at reasonable prices even under conditions of unfavourable monsoon. She was also deeply conscious of the linkage between food security and sovereignty in foreign policy. Maintaining adequate food reserves is an absolute must from the point of view of avoiding both panic purchase and famines, particularly at times when there are indications of aberrant monsoon behaviour. Some years ago the Government of India had over 60 million tonnes of foodgrain reserves and substantial quantities were exported to reduce the cost of maintaining stocks of that order.

‘To a people famishing and idle, the only acceptable form in which God can dare appear is work and promise of food as wages’ — these were the words of Mahatma Gandhi when he was healing the wounds arising from the Hindu-Muslim divide at Naokhali in 1946. He thus stressed the symbiotic bonds among work, income and food security.
 
Eradication of hunger and poverty is also the first among the UN Millennium Development Goals, which in my view represent a Global Common Minimum Programme for human security and well-being.
 
Achieving this goal is fundamental for achieving the other goals relating to education, gender equality, child mortality, control of HIV/ AIDS, malaria and other diseases and, above all, environmental sustainability. Unfortunately, progress in the reduction of hunger and poverty is poor in most developing countries excepting a few like China. FAO estimates that as a result of the rise in the prices of basic staples, about 75 million more people have been added to the list of those going to bed hungry during 2007. As a single nation, we in India have the largest number of malnourished persons in the world.

The post-independence history of our agriculture can be broadly grouped into four periods. Before describing them, I should mention that during the colonial era famines were frequent and Famine Commissions were abundant. The growth rate in food production from 1900 to 1947 was hardly 0.1 per cent. Most of the important institutional developments in agriculture emanated from the recommendations of Famine Commissions. The great Bengal Famine of 1942-43 provided the backdrop to India’s independence. It is to the credit of Independent India that famines of this kind have not been allowed to occur, although our population has grown from 350 million in 1947 to over a billion now.

The National Food Security Bill 2011, which is now on the website of the Union Ministry of Food and Consumer Affairs for public comments, aims to make the Right to Food a legal right. During the last seven years, the country has witnessed a transition from political patronage to legal entitlements in the case of education, information, work and land rights in tribal areas. When finally enacted, the Food Security Bill will be the brightest jewel in the crown of Indian democracy. Therefore, public scrutiny of the draft Bill is important. The draft Bill mentions that its aim is “to provide for food and nutritional security in human life-cycle approach by ensuring access to adequate quantity of quality food at affordable prices, for people to live a life with dignity”. Unfortunately the Bill is its present form will not be able to fulfill this inspiring objective.

The legal commitment contained in the Bill implies that every child, woman and man should have physical and economic access to balanced diet on the basis of a life-cycle approach, i.e., from conception to cremation. Nutrition security involves access not only to the needed calories and protein, but also to micro-nutrients like iron, iodine, zinc, vitamin A, and vitamin B12. In addition, clean drinking water, sanitation and primary health care are essential for ensuring that food is properly assimilated in the body.

During his visit to India, President Barak Obama pointed out that our country is fortunate to have a youthful population with over half of the total population of 1.2 billion being under the age of 30. Out of the 600 million young persons, over 60 per cent live in villages. Most of them are educated. Gandhiji considered the migration of educated youth from villages to towns and cities as the most serious form of brain drain adversely affecting rural India’s development. He therefore stressed that we should take steps to end the divorce between intellect and labour in rural professions.

The National Commission on Farmers (NCF)(2004-06) emphasised the need for attracting and retaining educated youth in farming. The National Policy for Farmers, placed in Parliament in November 2007, includes the following goal of the new policy:

To introduce measures which can help to attract and retain youth in farming and processing of farm products for higher value addition, by making farming intellectually stimulating and economically rewarding.

The country is at long last becoming sensitive to the serious consequences of the growing rural-urban divide in terms of investment, infrastructure and opportunities for income and employment. The rural-urban divide also leads to an expanding rich-poor divide. Since crop and animal husbandry, fisheries, forestry, and agro-processing are the main sources of rural livelihoods, the current agrarian crisis is adding to the problems of hunger, poverty and unemployment. According to the Union Planning Commission, we are off-track in achieving most of the UN Millennium Development Goals. A major cause for the growing rich-poor divide both between and within nations is unequal access to modern technology. Technology helps to achieve a paradigm shift from unskilled to skilled work and thereby move large numbers of the rural poor from the primary to the secondary and tertiary sectors of economic activity. If technology has been a major factor in promoting economic and social divides in the past, the challenge now lies in enlisting technology as an ally in the movement for economic, gender and social equity.

Norman Borlaug’s early upbringing in an Iowa farm and his experience of hardship during the US Depression of the early 1930s instilled in him the desire to bring science to address the problems of low farm productivity, poverty and hunger. After completing his Ph.D degree in Plant Pathology at the University of Minnesota in 1942, he joined the Rockefeller Foundation’s agricultural programme in Mexico, leading to the birth of the International Maize and Wheat Improvement Center (CIMMYT). There he began his work on wheat, concentrating on the control of stem, stripe and leaf rusts, the important diseases of the crop. He introduced a multi-pronged approach to manage the rust fungus, including the development of composite varieties characterised by phonotypic identity but genotypic diversity with reference to resistance to different races of the pathogen, an approach conferring enduring resistance as a result of reduced pressure on the fungus to mutate and create more virulent strains.

Bhutan has developed the concept of Gross National Happiness (GNH) as a substitute for Gross Domestic Product (GDP). In this theory, GNH comprises spiritual and cultural values, including love of sport, music, dance and spiritual activities. This is a good departure from measuring happiness purely from the view point of money. I would like to elaborate on four pillars that are necessary to uphold sustainable human happiness.

Ecology

There is an increasing awareness of the need for adopting sustainable lifestyles which will not make a heavy demand on our life-support systems of land, water, biodiversity, forests, oceans and climate. In his book titled World on the Edge.1 Lester Brown has described how we still have time to prevent environmental and economic collapse. Recent calculations on the ecological footprint each one of us is leaving behind shows that our per capita consumption of natural resources is exceeding the biocapacity of our earth. Soon we will need two planets to meet the growing demand for land, water, forests and biodiversity. In this context, we should keep in view what Mahatma Gandhi said long ago: 

An ancient Chinese proverb says

If you are thinking one year ahead, plant rice
If you are thinking ten years ahead, plant trees
If you are thinking hundred years ahead, educate the people

Subramanya Bharati, a great Tamil poet, wrote decades ago that nutrition and education were the two legs of a human being — nutrition for the body and education for the mind. We must, therefore, foster a movement for integrating academic excellence and social relevance in the curricula of our educational institutions. Our universities should promote the growth of the science of ecotechnology, which is the product of the integration of traditional knowledge with frontier science. This will need a mind-set change in relation to the knowledge and wisdom of our tribal and rural families.

In the 1990s, I developed the Iwokrama Rain Forest Programme, which represents the world’s largest adventure in the sustainable management of rainforests. The local Amerindian population welcomed me to Iwokrama with a song, which translates thus:

On August 6, 1945, the most dreadful among the weapons of mass destruction – the atom bomb – was dropped in the civilian area of Hiroshima. Three days later, another atom bomb was dropped in Nagasaki. In July 1955, Bertrand Russell and Albert Einstein issued their famous manifesto seeking the abolition of nuclear weapons and appealing to all inhabitants of Planet Earth:
 
Remember your humanity, and forget the rest. If you can do so, the way is open to a new Paradise; if you cannot, there lies before you the risk of universal death.

In 1957, the Russell-Einstein Manifesto led to the birth of the Pugwash Conferences on Science and World Affairs, an organisation devoted to the causes of ending the nuclear peril and reminding scientists of their ethical responsibility for the consequences of their discoveries, particularly in the area of nuclear threat to human survival.

Floriculture is increasingly regarded as a viable diversification from traditional field crops due to increased per unit returns and increasing habit of “saying it with flowers” during all the occasions. All over the world, the floriculture sector is experiencing rapid changes. Opening up to the world market in the WTO regime paving way to free movement of floricultural products world wide, globalization and its effect on income generation have all contributed to increase in per capita consumption of flowers in most countries. Noticeable feature of global floriculture is the development and expansion of floriculture in non traditional areas. Netherlands, Italy, Germany, and Japan had strong tradition for growing and consumption of flowers. The concept of commercial floriculture was perpetuated across the world from those regions. Now production centers are developing in Latin America, Africa and also in Asia to meet the demand of consuming countries and also to expand domestic market, commensurate with improved economic conditions, These countries provide highly qualitative floricultural products with low cost price which is finding a favourable place in markets of Western Europe, America and Japan. Emergence of new production centers has made floriculture more competitive and this in turn is benefiting the ultimate consumers.

Fruit ripening is a highly coordinated, genetically programmed and an irreversible phenomenon involving a series of physiological, biochemical and organoleptic changes which finally lead to the development of a soft edible ripe fruit with desirable quality attributes. Ripening is the process where changes take place in the fleshy fruit and make it edible. It represents the unique coordination of developmental and biochemical pathways leading to changes in colour, texture, aroma and nutritional quality of mature seed-bearing plant organs (Barry and Giovannoni, 2007). Physiologically mature fruit is transformed from an unfavourable state of firmness, texture, colour, flavour and aroma to favourable state for consumption. It is the final phase in the development of fruit and involves major metabolic changes and it is normally an irreversible event. The ripening phase does not start until the fruit has developed considerably from the tissues present at anthesis and it is difficult to stimulate ripening before it attains maturity. The ripening changes which are common during softening are accumulation of pigments and changes in cell wall.

Fruits are living commodities which continue to respire and transpire even after harvest. The storage life of fresh fruits is indirectly proportional to the rate of their respiration which in turn depends on the atmospheric gas composition in which they are stored. Normal air contains about 20.9% oxygen (O2), 78.0% Nitrogen (N₂) and 0.03% carbondioxide (CO₂). Lower levels of O₂ and higher levels of CO₂ in the storage environment result in reduced rate of respiration, delayed ripening and increased storage life. The reduction in O₂ concentration and increase in CO₂ concentration in the storage room with precise control and maintenance of these gases throughout the storage period is generally referred as controlled atmosphere (CA) storage.

CA storage is generally used for long term storage or long distance transportation of fruits in combination with low temperature storage. The use of CA storage for extending the post harvest life of fruits has increased steadily worldwide during the past 60 years. This trend is expected to continue with the advancement of technologies in attaining and maintaining CA during transport, storage and marketing of fresh fruits.