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India is bestowed by nature with a vast livestock resources comprising of 190 million cattle, 108 million buffalo, 135.17 million goats, 65.06 million sheep, 10.29 million pigs, 729.2 million poultry, 0.29 million mithun and 0.07 million yak (Department of Animal Husbandry, Dairying and Fisheries, 2014). The livestock sector is an important segment of agriculture and contributes nearly 25.6 percent of value in agriculture, fishing and forestry sector. The total share of livestock in GDP of India is 4.11 percent and meat is an important sector to generate foreign revenue by export. The share can further be extended by utilization of animal by-products because it is a sector of livestock neglected most. It is an old saying that ‘each and everything comes from animals can be utilized except last cry of animals’.

The utilization of biomass presents a promising avenue for addressing the challenges of resource scarcity, waste management, and environmental sustainability. This book chapter delves into the multifaceted applications of biomass, with a particular focus on the processing of straw, a versatile agricultural residue. From providing essential bedding material for animals and enhancing agricultural practices to playing a pivotal role in horticulture, cushioning, mulching, and composting, this chapter examines the diverse roles that processed straw assumes. Furthermore, it explores its significance in paper and cardboard manufacturing and its emergence as a renewable fuel source, underscoring how thoughtful biomass utilization paves the way toward a more environmentally conscious and resilient future.

Blood serves as a significant byproduct within the meat industry, and the  efficient management of its collection and processing is crucial for improving profitability. The amount of blood obtained from slaughtered animals typically ranges from 5-7% of their live weight. Despite diligent efforts, a portion of blood is inevitably lost during the slaughtering process due to spillage and various other factors. To reduce these losses, several essential practices can be adopted:
1. Effective slaughterhouse design: Enhancing the layout and operational procedures within the slaughterhouse can significantly minimize spillage. This encompasses the implementation of well-structured drainage systems and collection vessels.
2. Training and protocols: It is essential to ensure that personnel are thoroughly trained in blood collection methods and strictly follow established protocols to mitigate accidental loss. This involves appropriate handling and prompt processing to prevent clotting and spoilage.
3. Technology: Allocating resources towards advanced blood collection and processing technologies can enhance operational efficiency. Automated systems facilitate the collection, filtration, and storage of blood while minimizing waste.
4. Regular maintenance: Maintaining equipment and facilities in optimal condition is vital to prevent leaks and other complications that may result in blood loss.
5. Storage and processing: After collection, blood must be processed promptly to prevent coagulation. Efficient cooling and storage practices are essential for preserving its quality and maximizing its potential for subsequent processing into products such as blood meal or plasma.
Collection of Blood
Blood may be collected directly into metal or plastic drums when animals are suspended for bleeding. In cases where the animals are slaughtered on the ground, small enamel or plastic bowls can be placed under the bleeding site to collect the blood, which can subsequently be transferred into a drum. The anticipated yield of blood from average tropical livestock is generally as follows:

Bones, horns, and hooves represent essential by-products of the slaughterhouse sector. Frequently obtained from deceased or fallen animals, these by-products possess considerable applications both independently and in the production of secondary goods. Their use fosters the development of secondary rural industries, consequently creating employment opportunities for individuals in rural regions. Furthermore, by fully utilizing these by-products, producers can secure higher prices for their livestock, while processors may experience
enhanced profitability. Effective management of these by-products could also play a role in reducing the costs associated with meat and meat products.
Composition of Bone
Bone constitutes roughly 15% of the weight of a dressed carcass, although this figure may fluctuate due to variables such as breed, age, fat content, and overall health. Generally, the percentage of bone in a dressed carcass is assessed as the weight of the bones in relation to the total weight of the carcass post-dressing.
The bone content varies as follows:
• Young cattle and buffalo: 15% to 20% of carcass weight.
• Older cattle and buffalo: 20% to 25% of carcass weight.
• Pigs: 15% to 20% of carcass weight.
• Sheep and goats: 25% to 30% of carcass weight.
• Poultry: 30% to 35% of carcass weight.

Introduction

COVID-19, a worldwide pandemic, addresses a deflationary stun for the worldwide economy. The outbreak of coronavirus has had a significant impact on public health worldwide and all stages of various industries’ supply chain and value chain. The 2019 novel coronavirus (2019-nCoV) or the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is rapidly spreading from its origin in Wuhan City of Hubei Province of China to the rest of the world. The infection began in bats and was communicated to people by inhalation or contact with infected droplets, and its infection time frame goes from 2 to 14 days. Primary manifestations in hospitalized patients with COVID-19 include fever (98%), cough/hack (76%), and myalgia or weakness (44%). Severe complications include acute respiratory distress syndrome (ARDS), RNAemia, acute cardiac injury, and multiple organ failure. However, exaggerated immune responses may lead to Cytokine Storm. Cytokine storm syndrome includes ARDS, shock, and multi-organ failure (Zheng et al., 2020). Many people are asymptomatic also, and the severity of this disease varies from person to person. The fatality rate is estimated to range from 2 to 3%. Typical/low white cell checks can analyze it with raised C-responsive protein (CRP), periodic modernized tomographic chest examination. The infection spreads quicker than its two predecessors, the SARS-CoV and Middle East respiratory disorder Covid (MERS-CoV); however, it has lower casualty. The worldwide effect of this new scourge is yet questionable (Singhal, T. (2020).

Introduction

Enzymes are globular proteins that act as biological catalysts. They are produced by living cells to bring about specific biochemical reactions. Digestive enzymes catalyze the degradative reactions by which substrates (i.e., feedstuffs) are digested into their chemical components (e.g., simple sugars, amino acids, fatty acids) which in turn, are used for different body functions. Different enzymes are utilized for the complete digestion of complex feed. The enzymes are being used in the feeding industry from last several decades. Various digestive enzymes have been studied for use as feed additives to enhance animal performance They are commonly used to improve the nutritive value of feeds for non-ruminants (especially, poultry and swine). They are not routinely used in adult ruminant diets because the fibrolytic activity within the rumen environment is normally very high, and it is assumed that exogenous enzymes cannot survive proteolysis in the rumen (Kopency et al., 1987). Forages are the main feed component that serve as the major source of energy available to the animal in ruminant production system. However, due to slow or incomplete digestion of fibrous substrates only 10 to 35% of energy intake is available as net energy that significantly limits livestock performance and profits in production systems. To improve the ruminal fibre degradability many strategies have been developed to stimulate the digestion of the fibrous components in ruminant feeds. That includes, use of various feed additives which stimulates fiber digestion, physical and chemical processing of feeds in order to enhance the rate and extent of fiber digestion. However, the use of “natural” product to enhance production efficiency is highly recommended that can potentially play some role in replacing performance benefits vacated by antibiotics and hormones. Enzymes are proteins that are ultimately digested or excreted by the animal, leaving no residues in products, which was a major drawback in the use of antibiotics and hormones.

Abstract

The present study was conducted to develop ready to eat extruded snack food based on germinated flour of wheat, Bengal gram and green gram. A Central Composite Rotatable Design (CCRD) for five variables at five levels was used for experimental combinations and optimization of the process parameters. Experimental design with green gram flour (5 to 20%) and bengal gram flour (1535%) in wheat flour, moisture content (14-18%), screw speed (200-300 rpm) and barrel temperature (126-134°C) as independent variables having 32 different combinations of snack formulations that were studied using response surface methodology to investigate the effect of these variables on product responses (Lateral expansion, bulk density, Water absorption index, water solubility index and sensory characteristics). Sensory analysis was carried out of all extrudates for texture, color and overall acceptability. Multiple regression equations were obtained to describe the effects of each variable on product responses. The optimum operating conditions for development of germinated wheat, green gram and Bengal gram flour extrudate were 132°C of barrel temperature, 275 rpm of screw speed, 17 % offeed moisture, 6.5% of green gram flour and 23.1% of Bengal gram flour. The responses predicted by the software for these optimum process conditions resulted lateral expansion of 169.59%, bulk density, 0.263g/cm³; water solubility index, 19.08; water absoption index, 13.88g/g; and overall acceptability value of 7.38.

Animal organs and glands play a crucial role in both nutrition and medicine. These organs encompass the brain, heart, liver, lungs, spleen, tongue, pancreas, udder, stomach, uterus, testes, thymus, kidneys, parathyroid, adrenal glands, and ovaries. Some of these are consumed as food, while others find application in medical practices. Glands, constituting approximately 0.28% of an animal’s total weight, are regarded as valuable by-products of meat production and are increasingly utilized in contemporary medicine for the extraction of beneficial substances. The secretions from both endocrine and exocrine glands are essential for the growth and functioning of the body, with hormones derived from these glands being employed to address deficiencies and serve as therapeutic agents.
1. Human consumption: The majority of glands are ingested alongside meat; however, in the case of cattle and buffalo, ovaries and testes are typically discarded, while other glands are consumed. In smaller animals, it is common to eat all glands with the exception of the ovaries. The liver is especially prized for its rich nutritional profile, being abundant in vitamins A, D, and B complex, which are advantageous for conditions such as poor vision, bone development, and anaemia.
2. Medicinal uses: Glands are responsible for producing hormones that offer significant medicinal advantages, including the treatment of anaemia, diabetes, and various other health issues. They also contribute to the development of secondary sexual characteristics in both males and females. Extracts derived from these glands are invaluable for restoring hormonal deficiencies within the body. The incorporation of animal glands into pharmaceutical manufacturing represents a notable advancement in modern science. In Western nations, there has been a
concentrated effort on the efficient collection and utilization of these glands, acknowledging their economic significance for slaughterhouses and the meatpacking sector.

The intestines of domesticated animals, which are a byproduct of slaughterhouses, are employed in numerous applications. Intestines that function as food containers are referred to casings. Non-consumable uses encompass catgut, strings for musical instruments and rackets, along with various other specialized applications. Additionally, intestines can be ingested following meticulous cleaning and cooking with spices. Among these applications, sausage casings yield the highest profit. Different nations exhibit distinct preferences for sausages, and these preferences frequently determine the varieties of casings utilized.
In addition to intestines, casings can also be sourced from weasands (oesophagus), urinary bladders, stomachs, and rectums. Although artificial casings made from plastic materials and hydro-cellulose are prevalent in Western nations, natural animal casings continue to be in high demand due to their distinctive properties. Natural casings, which are obtained from the intestines or other parts of animals such as sheep, pigs, or cows, undergo processing to become edible and are utilized in the production of sausages and other processed meats. They are esteemed for their elasticity, enabling them to conform to the shape of the sausage filling, and they play a crucial role in enhancing the flavour and texture of the final product. Natural casings, are frequently favored for traditional or artisanal sausages because of their authentic origin and their capacity to improve the taste and visual appeal of the sausages.

Abstract

Agricultural practices prior to the eighteenth century were completely dependent on crop landraces and their mixtures. The knowledge of plant genetics and its application to crop improvement programmes led to increase the production potential of agriculture. Contrary to this, the wonders of crop improvement have resulted in the erosion of genetic diversity of many crops in farmers’ fields, including wheat, due to the replacement of landraces and farmers’ old cultivars with modern high-yielding cultivars.

Wheat is cultivated over an area of 216.6 million hectare globally and the production is 674.9 million tons. The seven largest producers of wheat are China, India, the Russian Federation, the USA, France, Turkey and Canada. During 2012-13, India produced 92.46 million tons of wheat from 29.65m ha area with productivity of 31.19q/ha (4th Advance Estimates, Directorate of Economics and Statistics, Government of India). Three wheat species namely, T. aestivum L., T. durumDesf. and T. dicoccumSchubl are grown in India as commercial crops covering 95, 4 and 1 percent area, respectively. The cultivation of T. dicoccumis confined largely to the regions of Karnataka and Maharashtra.

1. Introduction

Plant is probably the greatest gift of nature. Plants provide us with food, cloth, house, papers and many others. Some of the plants have medicinal values and are known as ‘medicinal plants’. Our ancestors used these plants not only for protection from diseases but also for the treatment of several ailments. China has the highest number of the medicinal plants used (about 11,500 species) followed by India (about 7500 species). People of other countries also use medicinal plants in varying amount (Rafieian-Kopaei, 2013). Tradition is still going on. It is reported that even today 80% of the world population relies on medicinal plants in their medication (Hamilton, 2004). Few plants secrete essential oils full of aroma and are called ‘aromatic plants’. These plants are being utilized in industry for the production of essence and many other products. Medicinal and aromatic plants (MAPs), therefore, are in continuous use from past to present. In future also there will be tremendous scope of utilization of MAPs in drug discovery, aromatherapy, as cosmeceuticals, nutraceuticals as well as in animal husbandry. Present review will focus utilization of Medicinal and Aromatic Plants (MAPs) in past and present and its possible prospect in future.

Introduction

Whey is the serum or watery part of the milk that remains after separation of curd that result from the acid or proteolytic enzyme mediated co-agulation of milk. It is major by product of dairy industries manufacturing products like channa, paneer, cheese and chakka (Sharma and Bhatia, 1999).The current world production of whey is estimated at about 165 million tones, in that cheese whey accounts for nearly 95 % of total whey. In India near about one million tonne of whey is annually derived, in that major source of whey is from the production of channa, paneer and shrikhand production. This is mostly thrown away as a waste which creates environmental pollution, also in that way about 70, 000 tonnes of Nutritious solids are lost (Puranik, 1999).

A. Answer the following questions:

1.    What is NPN substances?

Ans: Feedstuffs which contain nitrogen in the form other than protein or peptides aretermed as non-protein nitrogen (NPN).

2.    What is liquid diet?

Ans: Liquid molasses containing 2-3% of uniformly mixed urea fortified with minerals andvitaminsis named as ‘liquiddiet’.

3.    Name few amides.

Ans. Urea (46.6% N) and Biuret (35%N)

4.    Name few amines:

Ans. Histamine from Histidine, Tryptamine from Tryptophan, Tyramine from Tyrosine, Betaine from Sugar beet pulp.

5.    Name few alkaloids.

The poultry industry generates by-products that encompass all materials derived from farms and processing facilities that are not intended for human consumption. These by-products can be classified as either edible or inedible. The edible by-products primarily consist of tissues and bones extracted from poultry carcasses. Conversely, inedible by-products comprise hatchery waste, which includes infertile eggs, deceased embryos, dead chicks, and eggshells, as well as feathers, blood, offal, fat, and manure. These by-products are typically divided into three categories:
1. By-products from the production phase, which consist of litter and manure sourced from the farm.
2. By-products from hatcheries which include materials originating from the hatchery, such as the shells of hatched eggs, dead embryos, infertile eggs, and deceased chicks.
3. By-products from the poultry processing plant, which encompass blood, feathers, offal (including feet, heads, and intestinal tracts), condemned birds etc.
1. By-products from the production phase: Poultry litter and manure from caged layers are extensively utilized as a protein supplement in the diets of both poultry and livestock. Following sterilization and dehydration, poultry manure can be integrated into feed, containing approximately 27-29% protein. It can be incorporated into the diets of broilers at levels of up to 20% and layers at 25%. In addition to their application in animal feed, poultry manure and litter are valuable as a ‘surface dressing’ for agricultural fields. They function not only as effective fertilizers but also improve soil texture. One ton of deep litter yields approximately 29.48 kg of nitrogen (equivalent to 136.08 to 147.42 kg of ammonium sulphate), 20.41 kg of phosphorus (equivalent to 113.40 to 136.08 kg of ordinary superphosphate), and 20.41 kg of potash (equivalent to 45.34 kg of potassium), along with 6.80 kg of magnesium, 6.80 kg of sodium, and 27.21 kg of calcium. Furthermore, poultry manure is rich in trace elements such as boron, copper, iron, sulphur, and zinc.

12.1 Introduction

Performance of an orchard mostly depends on the availability and quality of land and water resources and their management in fruit production. Before taking a decision on all the other possible alternatives under consideration, it is important to undertake feasibility study of the available resources to the orchard management. Other conditions in the growing environment, such as climate and weather conditions, disease and pest management and other factors affecting crop growth also affect production. With ever increasing population in India, today the major problem confronted in fruit cultivation is to improve or at least sustain the production to meet ever increasing demand for fresh or processed fruits. Fruit production can vary widely in response to management of available resources. India cannot afford to mismanage its natural resources (Sharma, 2012). Therefore, judicious utilization of available resources should be done. The following resource constraints are required to be judiciously handled in the management of fruit orchards:

1. Land and Soil management
2. Irrigation water management
3. Solar radiation management

Continuous vegetable cultivation year round in the limited available land, without adopting crop rotation practices induces stress, which leads to low vegetable crop productivity. These conditions apart from building up soil-borne pathogens will also lead to other deleterious factors such as temperature extremes, flooding, drought, salinity, heavy metal contamination, insufficient nutrient uptake, soil pH stress, etc. causing severe crop loss. To overcome these abiotic stress conditions, grafting is an environmentally friendly technique for reducing losses in production in solanaceous and cucurbitaceous vegetable crops. The cultivated area of grafted Solanaceae and Cucurbitaceae has increased tremendously in recent years because the objective of grafting has been greatly expanded (Lee et al., 2010) to reduce infections by soil-borne pathogens and to enhance the tolerance against abiotic stresses.

Introduction

Fish and shellfish constitute an important component of global nutrition. Fish protein is an essential source of nutrients for many people, especially in developing countries. Health benefits of fish oil in preventing heart attack and other cardiovascular diseases are well appreciated. Mounting evidences suggest that the benefits of fish consumption are not limited to the well-known effects of fish oil alone. Fish is also a rich source of protein containing all essential amino acids, which is required for the body maintenance and muscular build-up. The protein content in most of the raw finfish meat is in the range of 17 to 22% (g per 100 g), while the cooked portions of some fish such as tuna may have as high as 30% protein. The amino acid score of fish protein compares well with that of whole egg protein, which is considered as a standard protein source. Fish is also rich in the non-protein amino acid - taurine, which has a unique role in neurotransmission. Apart from nutritional properties, fish proteins also possess a number of functional properties such as emulsifying, foaming, gel forming, water binding and fat binding properties, which are important in product formulations. These functional properties are mainly attributed to the major meaning myofibrillar proteins, actin and myosin.

During the processing of fish only the fillets are generally retained while the bulk of product (up to 66%) is discarded. About 30% of the total fish weight remains as waste in the form of skins and bones during preparation of fish fillets. This waste is an excellent raw material for the preparation of high value products including protein foods. The utilization of fish wastes help to eliminate harmful environmental aspects and improve quality in fish processing. Skin and bone are sources of high collagen content. The average quantity of waste generated during fish and shellfish processing operations (based on average annual marine landing data) is indicated in Table 1.

The commercial aquaculture for crustaceans in India has become a huge success due to the introduction of new species, the improved hatchery production of seeds, scientific management of culture practices and the availability of good quality feed and other input. Introduction of new species like Letopenaeus vennamei has resulted in increased yield and productivity. The farming of this species has already been established in coastal Andhra Pradesh, Karnataka and Tamil Nadu and gaining momentum in Kerala and other states.

Similarly, farmers in both coastal and land locked States have gone for large scale farming of Giant Freshwater Prawn (Macrobrachium rosenbergii) popularly called “Scampi” which is having high demand in both domestic and international markets. In order to meet the raw material requirement of large number of processing units established for export and also to meet the domestic demand. The state of Andhra Pradesh accounts for more than 50 per cent of the cultured Scampi production and also in terms of area under culture. During the year 2013-14 the estimated production of L. vannamei was 406018 tons whereas the black tiger export of cultured prawn from the country was to the tune of 41947 tons and that of scampi, it was 1401 tons (MPEDA 2008).

Industrial processing of prawn results in huge quantities of waste in the form of head and shell. Since the exported shrimp products are mainly of peeled items, the shell waste produced is quite high. The head and shell constitute nearly 60% by weight of the whole prawn depending on the species and size. In India its availability is estimated to be 100,000 tonnes annually and it is the single largest fishery waste of the country. Crab shell and squilla are other important raw materials available from marine sector.

Fat
• Utmost significant slaughterhouse byproduct is fat obtained from intestines, kidneys, channel and other offals
• Edible ox fat is rendered and the obtained product is called premier jus (higher grade fat) which is differentiated into oleo oil and oleo stearin
• If all edible ox fat is rendered, it is called dripping and it used for human consumption
• Inedible fat is used for soap manufacturing
• The highest value fat from pig is recovered from peritoneal lining (leaf fat), and the subsequent highest value recovered from back fat, mesentery and omentum
• Sheep fat is separated into oleo oil and oleo stearin because of its strong flavour
• Mutton fat is harder and its stearin content is more than ox or pig and therefore, it is applied on the top of meat paste glass jar as a protective layer
Rendering of edible fat
Three principal procedure of rendering of edible fat are:
i. Wet rendering
ii. Dry rendering
iii. Continuous low-temperature rendering

11.1 Introduction

Fermented foods are the result of the activity of a few specialized types of micro-organisms among the thousands of species known to mankind. Success of such processes is depended upon the control of environmental conditions ensuring the growth of the desired microbial species and inhibition of others. The fermentation can be broadly defined as the process in which the carbohydrate or like compounds are broken down, under anaerobic or aerobic conditions [171]. The basic role of micro-organisms is to breakdown the organic compounds to get energy for their metabolic activities. From ancient times, people all over the world have developed traditional processes for production of alcoholic beverages (wine) either from natural sugar such as in wine or by degrading the starchy materials (beer). Fruit wines referred to as ‘Soma’ in our ancient scriptures have been part of food of man and were used as medicine, might have originated accidentally (transformation of fruit juice beverages having exhilarating or stimulating properties). Wines are made principally from fruits like grape or extract of other fruits of various types (table wine, sparkling wine, dessert, aperitif or vermouth and pop wines) while the beers are prepared from grains like barley, rice and corn. The principal carbohydrate in grain is starch which can not be fermented directly. This process is brought about by starch splitting enzymes by germinating the grains followed by drying and storage until needed. Distillation of beer produces a variety of liquors (whisky, rum, gin, vodka), while that of wine produces the brandy. Besides, the improvement in the raw material selection, fermentation conditions and techniques, a lot of waste material is generated during fermentation process in the industries. Nevertheless, the food based industries are significant contributors to the economy of the many countries of the world (Fig 1). The global market value of food fermentation based industries is estimated to be around 250 million US dollars. Interestingly, more than 10% of this accounts for alcoholic beverages (Fig 2) with projected increase of US$ 27 billions in 1989 to 40 billions in 1990 [93,123,123,129].

1. INTRODUCTION

Wild fruits are highly nutritious and contain vitamins, carbohydrates, protein and minerals in higher quantity than majority of other common cultivated fruits. They are also a rich source of several bioactive substances, compared to the cultivated fruits. In India,these wild fruit trees grow abundantly across an altitudinal gradient of Himalaya and the majority of them bear fruits during summer. Fruit varieties are consumed by the local inhabitants of the region. At the same time, there are numerous under exploited species of wild fruits having high potential for exploitation viz., Bael (Aegle marmelos CL.), Berberis asiatica DC, Seabuckthorn (Hippophae sp.,) Rubus sp., Prunus armeniaca L., Karonda (Carissa carandas L.) Bitter Almond (Prunus amygdalus Batsch Smith), Feijoa sp. Among the wild fruits, Hippophae sp.was found to be economically efficient, followed by Aegle marmelos, Rubus ellipticus Smith, respectively. Wild apricot (Prunus armeniaca L.), a semi-domesticated and less utilized fruit of the higher Himalaya, provides better economic returns on an annual basis. Attempts have been made to utilize these wild fruits as a source of income, particularly for poor rural inhabitants and unemployed youths of the region by making a variety of edible products such as jam, jelly, juice, squash, sauce, wine etc. Here in this article, production of wine, vermouth and brandy from wild fruits would be focused. But before discussing preparation of wine and brandy in detail, we shall be describing the general process of wine and brandy making first, then the products from the specific wild fruits.

Introduction

A concept focused on crop and livestock production with minimal environmental impact has emerged as a result of the paradigm shift in Indian agriculture from traditional to sustainable agriculture. This concept also supports the farm economy and helps farmers improve their tactics and quality of life. This has sparked farmers’ interest in learning traditional technology skills that draw on local knowledge that people have acquired from their ancestors to address issues in agriculture and activities associated with natural processes. Indigenous Technical Knowledge (ITK), which is a component of using natural products to address agricultural problems and integrate activities, has attracted interest since the concept of sustainable agriculture began to emerge in the Indian state of agriculture in the late 1980s. ITK is regional knowledge unique to a particular culture or community.

At the beginning of the 21st century, the world is facing a number of major global challenges. On the development side one of these challenges is the establishment of sustainability. In the context of agricultural development, a new agenda has been set to achieve the goals of producing and disseminating economically viable, socially acceptable and environmentally sound technologies that are geographically sound. , even local agricultural schools cannot teach such knowledge because of its size and diversity (Pereira, 1993).

1. Introduction
Global food insecurity is a prominent concern today, and this concern continues to haunt with exponential population growth, coupled with significant climate changes. The global population has increased at a rapid rate to around 8 billion in number which has led to a corresponding rise in food demand worldwide (UNFPA, 2023). Consequently, ensuring ample crop production has emerged as a primary objective for the entire world. According to World Bank (2023), an important strategy to bring down extreme poverty levels, fostering shared prosperity and providing sustainability for the expected population rise of 9.7 billion is agricultural development by 2050. Nevertheless, optimizing the productivity of a crop is never an easy task. Crop plants continuously face exposure to different abiotic and/or biotic factors, which retard growth and development processes ensuing their reduced productivity and diminished crop quality. Agricultural crops are vulnerable to biotic stresses such as bacteria, nematodes, fungi and herbivores. In addition to biotic factors, these challenges are further exacerbated by abiotic stresses like flooding/waterlogging, drought, temperature variations, soil salinity/alkalinity, heavy metals, nutrient deficiencies and CO2. They have a detrimental impact on crop at different stages of plant growth, ranging from entire plant to tissue and sub-cellular structures. Moreover, the abiotic stressors cause a direct impact on crops by inducing protein denaturation and aggregation, while also increasing the fluidity of membrane lipids (Kumari, 2022). According to Oshunsanya et al. (2019) major abiotic stresses i.e. extreme temperatures, drought, and nutrient deficiency/toxicity, contributes to significant annual crop yield losses ranging from 51-82% worldwide. On the other hand, yield penalties due to waterlogging merely is supposed to increase from 3–11% today to around 10–20% by 2080 (Liu et al., 2023). Daryanto et al. (2016) reviewed the published literatures from 1980-2015 and reported global yield reductions due to drought estimating around 21 % and 40%, respectively in wheat and maize.

Introduction

As per the International Society of Horticultural Sciences (ISHS), horticulture encompasses the cultivation of various crops in limited spaces, including fruits, vegetables, flower, tree, aromatic and medicinal plants. Horticultural products encompass all items, whether in their raw or processed form, that have originated from horticultural crops and practices. The main sectors of horticultural science includes a large number of products like fruits from trees vines and bushes; nuts from perennial trees and bushes; fruits, roots, shoots stems, leaves, and flowers of annual vegetable crops; foliage of aromatic plants and leaves, bark, seeds and roots of medicinal plants and trees. Additionally horticultural products include cut flowers, potted ornamental plants, and bedding plants, which can be annual or perennial, along with trees, shrubs turf, and ornamental grasses cultivated in nurseries for landscaping purposes.

Introduction

The maritime industry, a cornerstone of global trade and commerce, has always been a complex and challenging domain. With the vastness of the world's oceans and the diversity of activities that take place within them, effective monitoring and management of maritime activities are crucial. This is where Systems for Monitoring Vessels come into play. VMS are a form of satellite based surveillance system designed to monitor the location, course, and speed of vessels. They provide real-time data to maritime authorities, contributing to the safety, security, and sustainability of marine operations.

Pulse crops provide nutritious food, feed and fodder and thrive well in fragile eco-systems where other crops often fail. They have the ability to trap atmospheric nitrogen in their root nodules in association with Rhizobium, bringing qualitative improvement in soil health i.e. physical, chemical and biological properties of the soil.  These virtues enable pulse crops to remain an integral part of subsistence farming system of semi-arid tropics as well as of Indo-gangatic plains. The role of pulses has also been recognized for sustaining soil productivity under intensive cropping systems in irrigated conditions.

Pulses are an essential source of protein in the diet of the vegetarian population. Cultivation of pulses has been a long-standing tradition in Uttarakhand, where the availability of alternative sources of protein such as meat and milk is barely sufficient to fulfill the daily dietary requirements. Pulses assume big importance in these rainfed and environmentally harsh regions by being an ideal crop for the prevalent low-input agricultural conditions. In Uttarakhand, pulses not only form the major constituents of the staple diet but also serve as an important source of feed and fodder for the livestock. Pulses also improve the soil health by fixing atmospheric nitrogen as well as by increasing soil organic matter

Air, water and land constitute our environment and these are technically known as atmosphere, hydrosphere and lithosphere respectively. All these spheres together constitute the biosphere. In the biosphere, apart from human beings, plants, animals, birds, fishes, insects and microorganisms also exist. All these living beings get affected whenever a change, physical or chemical occurs in the biosphere. This change is termed as pollution and the agents that institute these changes are called pollutants. A kind of pollution that has come in to prominence more recently is radiation, causing environmental and health problems of immense magnitude. The radiation may either be natural like cosmic radiation from outer space and sun?s radiations or produced by disintegration of naturally occurring and manmade elements. Such radiation is not visible to our eyes, but can penetrate the body and do immense harm. Man and animals have been continually exposed to different sources of radiation. But the radiation levels were well within the tolerable limits in the past. Yet, since the mid 1970?s human activities have been changing the chemistry of atmosphere in a way that reduces the amount of ozone in the stratosphere which is responsible for protecting the living things from excessive amounts of ultraviolet radiation. Further, it is only after the advent of nuclear power stations that radiations increased to reach harmful levels. Though mankind has benefitted by harnessing nuclear energy for peaceful purposes, one cannot deny the inherent dangers of radiation. Nuclear power plants no doubt help in the production of controlled electricity. However, a worldwide controversy is ragging over the existing nuclear power plants and setting up of new plants particularly since 1986 disaster of Chernobyl nuclear plant in Russia. A fire in the plant allowed massive amounts of radiation to be released into the atmosphere. This fall out drifted into the Scandinavia and Eastern Europe causing enormous damage to crop and livestock.

Cotton (Gossypium) seed meal (CSM), the by-product of cotton seed oil industry, is widely used as an animal feed. However, its utilization as an animal feed is limited due to the presence of gossypol, a polyphenolie binaphthyl aldyde, which is toxic to non-ruminants such as poultry and swine and young ruminants such as calves and lambs. The gossypol (free gossypol, FG) present primarily in the pigment glands of cotton seed, is mostly converted to bound gossypol due to condensation of aldehyde group with free amino groups of proteins to form a schiff base. Formation of schiff base though results in the detoxification of gossypol to some extent, it also lowers the nutritive value by reducing the availability of lysine, the limiting amino acid of cotton seed. Thus, bound gossypol, consequently total gossypol (TG) (free plus bound) content is an important factor of cotton seed meal.

Abstract

The substantial loss in the shielding ozone layer has resulted in an increase in the solar ultraviolet radiation (UVR) on the Earth’s surface, which is detrimental for all living organisms ranging from prokaryotes to eukaryotes, including humans. This has augmented the scientific concern and interest in searching for the photoprotective compounds from diverse organisms. Cyanobacteria, the primitive O2-evolving photosynthetic prokaryotes are solely dependent upon the solar radiation for their energy requirement and thereby have to always face the UV-B stress. UVR affects cyanobacteria either directly or indirectly by inducing oxidative stress. In response, they have evolved the capacity to synthesize, accumulate and metabolize a variety of UV-absorbing compounds such as, mycosporine-like amino acids (MAAs), scytonemin, carotenoids, biopterin glucoside, as a strategy to reduce the direct and indirect damaging effects of UVR.

Abstract

Being an obligate photoautotroph, cyanobacteria must cope with a wide range of fluctuating environmental factors, including high light and ultraviolet radiation (UVR) that may lead to oxidative stress by upsetting the cellular redox status. Photo-induced oxidative stress by means of oxidizing agent such as reactive oxygen species (ROS) may damage several biological processes. In response to several adverse effects of solar UVR, cyanobacteria have developed different strategies such as heat dissipation mechanisms, synthesis of UV- absorbing/screening compounds and antioxidant systems to overcome the detrimental effects of intracellular oxidant molecules. This review deals with UV-induced oxidative stress and their counteracting mechanisms operating in cyanobacteria.

Vacuole: A fluid filled space within the cytoplasm surrounded by membrane called as tonoplast, that occupies most of the volume of cell. Aside from storage, the main role of the central vacuole is to maintain turgor pressure against the cell wall.

Valinomycin: An antibiotic that uncouples electron transport and oxidative phosphorylation only in presence of some cations such as K⁺ or Na⁺

Van der Waals interaction: Weak intermolecular forces between molecules as a result of each inducing polarization in the other.

Vaccaria hispanica (Mill.) Rauschert. (Syn. Saponaria vaccaria L.) (Caryophyllaceae): Eng.- Cow Soapwort/ Cow Basil [W]. Annual herb,as weed of orchards.Plant has blue-grey, waxy herbage and pale pink flowers. Used traditionally to relieve body swellings.

Validity: The concept of validity can be applied to every aspect of the research  process. In its simplest form, validity refers to the appropriateness of each step in finding out what is set out to. However, the concept of validity is more associated with measurement procedures.

Vacreation: The pasteurization of the milk or cream under reduced pressure by direct steam is called vacreation. This process removes feed and other volatile flavors from cream and to pasteurize it for butter making. This is also called vacuum pasteurization (Plate 623).

Vacuum: The state of negative pressure. It is equal to atmospheric pressure minus absolute pressure.

Vacuum cooling: A technique of cooling vegetable (leafy vegetables, asparagus, brussels sprouts) having a high surface to volume ratio; rapidly and uniformly by boiling off some of their water at 10C and at low pressure (5 mm of Hg) into a sealed container. The produce is cooled by evaporation of water from the tissue surface and is more rapid than hydro cooling (Plate 624).

Vacuum drier: A drier used to dry heat sensitive products where low pressure lowers the temperature, helps to retain natural flavour and minimizes oxidation and browning is called vacuum drier (Plate 625).

Vacuum cooling: It is a technique based on liquid evaporation which produces a rapid cooling effect in products containing free water. Suitable only where removal of the free water will not cause structural damage and where there is no barrier, e.g. a thick wax cuticle, to water loss. Subjecting suitable products to vacuum pressure allows part of the water contained in them to boil out at relatively low temperatures. Used successfully in reducing postharvest deterioration in fruits and vegetables, thus prolonging shelf life, during processing of some products, including liquid foods and bakery products, and rapid cooling of cooked meat, fish products and ready meals.
Vacuum drying: Removal of liquid from a solid mate rial while in a vacuum system, to lower the temperature at which evaporation takes place and thus prevent heat damage to the material. It may be used with frozen food.
Vacuum evaporation: Concentration technique in which the use of high temperatures is avoided by subjecting the substance to a vacuum, causing it to boil at a lower temperature. The process is performed in a chamber surrounded by a water jacket through which water is circulated to control temperature. Particularly useful for products where heat-induced protein de- naturation should be avoided, e.g. liquid egg whites and skim milk.
Vacuum flask thermostat: An electrically or mechanically operated instrument which monitors the temperature in an enclosure and if it deviates from a preset value increases or reduces the energy input to or abstracts more or less energy from the space to maintain the preset temperature. Commonly used in gas or electric ovens, refrigerators and freezers, deep fat fryers, slow cookers and the like.

VAM fungi are of worldwide distribution. They are present in the soil in form of chlamydospores, zygospores and azygospores and have been recovered from the soils of a variety of habitats e.g. agricultural fields, nutrient deficient soils, sand dunes and deserts, industrial wastes, sodic soils, polluted sites, sewage, eroded sites and others like forests, open woodlands, scrub, savana, heaths, grasslands, anthracite and bituminous coal wastes. There are several reports of VAM fungi from diverse habitats from India.

VA-mycorrhizal associations occur widely throughout the plant kingdom. They have  been reported to be present in Bryophytes, Pteridophytes, Gymnosperms and Angiosperms in nearly all the geographical regions of the world. Most of the agricultural and horticultural crops belonging to diverse families have been shown to form VA-mycorrhizae. Many species of plants of economically important families have been reported to be mycorrhizal. Likewise, many of the plantation crops like coffee, tea, citrus, timber trees, many of the fruit trees and medicinal plants have been shown to form VA-mycorrhiza.

Favourable effect of VAM association in plants has been attributed to an increased nutrient uptake by mycorrhizal roots. The transfer of ion from the soil to the roots by mass flow or by diffusion depends on the mobility of that particular ion in the soil. Ions such as NO₃^- ,SO ₄^— and Ca⁺⁺ may move rapidly through the soil to the roots by mass flow, and uptake would be limited by the absorbing capacity of the roots. On the other hand, ions such as H₂PO₄^-, NH₄⁺, Zn⁺⁺ and Cu⁺⁺ are poorly mobile and move to the roots by diffusion, the rate limiting steps is likely to be the movement to the root surface. Under such conditions, it is expected that uptake would be increased if ions could be moved rapidly through extramatrical hyphae of the VAM fungi rather than diffusing slowly through the soil. It is now well established that VA mycorrhizae enhance the uptake of phosphate by the roots but it is likely that they can also assist in the uptake of other ions. The following account provides an information on the findings of Indian mycorrhizasts on the effects of VA mycorrhizal association on nutrient uptake in the plants and its physiological implications.

Mycorrhiza research is relatively recent. Although, it was in 1885 that A.B. Frank made reference for the first time to the term “Mycorrhiza”, it took him nine more years to establish the symbiotic relationship between the fungus and its host plant. It took a much longer time to convince the rest of the scientific community of the validity of Frank’s theory. Researches carried out between 1917 to 1950 confirmed that “Mycorrhizal colonization is a beneficial symbiosis between tree and fungus”. It is an unique partnership in nature, where the higher plants share their photosynthates with their fungal partners and provide them shelter, the fungal partners in return provide protection to the root system and assist it in performing its functions especially anchorage and absorption of nutrients / water from soil more efficiently.

The ectomycorrhizal fungi have been in use as a biological tool in improving the performance of forest trees since long. Better performance of forest trees is ensured by making them mycorrhizal, employing efficient strains of ectomycorrhizal fungi.

Extensive studies have been carried out to explore the possibility of using mycorrhizal model system in inducing suppressions of potential soil-borne pathogens. Its relevance becomes all the more important since most of the soil-borne diseases, by and large, are not easily controlled by conventional methods.

Diseases due to Fungal Pathogens

Most of the studies conducted on the interaction of VAM fungi and fungal pathogens suggest that mycorrhizae decrease the severity of disease, while a few studies suggest that there is either no effect or there is an increase in the severity of disease. It has been pointed out that in view of the fact that VAM fungi deter the severity of disease they may be used as biocontrol agents. Various mechanisms by which VAM could suppress the fungal pathogens have been suggested on the basis of experimental evidences.

During the last thirty years, there has been a growing appreciation of the impor tance of VAM fungi in improving the plant growth and yield. They have been extensively studied also in India. Considering the potential importance of these organisms in the recovery of disturbed sites and their possible use in land reclamation, researches regarding their relationship to ecosystem recovery have now been initiated also in India.

Large areas of land in the country called wastelands are degraded and lying unutilized due to various constraints. Part of it called culturable, has the potential for the development of vegetation cover. On the other hand, part of it called unculturable, has no potential for the development of vegetation cover. In addition to these natural wastelands, there are large tracts of wastelands created due to human activities such as mining, deforestation etc. Such wastelands are also culturable and a vegetation cover can be developed on them after removing the constraints with some efforts.

Since a method to cultivate VAM fungi in pure culture is not available as yet, clean and high quality VAM inoculum production is not possible. However, VAM technology is gradually getting a place in agriculture as well as reclamation and afforestation programmes. The inoculum currently being used includes infested fields soils, sievings from such soils, soil and roots of greenhouse plants, or pot culture inoculum derived from surface disinfected spores of a single VAM fungus on a host plant grown in a sterilized growth medium. Attempts are being made to manipulate VAM fungi, rooting media, hosts and fertilizers in order to secure superior quality of inoculum by these methods on a large scale. In addition, other techniques like tissue culture, hydroponic system etc. are also being attempted to cultivate VAM fungi in pure culture. The Indian mycorrhizasts have also attempted to devise and develop improved methods for production and storage of commercial VAM inoculum. The following description gives an account of Indian work related to production and storage of consistently high quality disease free VAM inoculum.

Of the various microorganisms present in and around roots, VAM fungi occupy unique ecological position as they are partly inside and partly outside the host. Their internal phase encounters competition and antagonism from other beneficial symbiotic microbes while their external phase faces competition and antagonism from beneficial non-symbiotic microbes present around the roots. Since they have an ensured source of nutrients from the host, they have comparatively better conditions for their growth and may exert greater effect on plants with other symbiotic and non-symbiotic microbes in and around their roots. It has been pointed out that investigations are needed on the interactions between VAM fungi and these beneficial microbes, and their effect on growth and productivity in plants. A bulk of information has been collected related to this aspect; however, authentic generalization has not been possible as yet. Following description gives an account of the work done by Indian mycorrhizasts on the interactions between VAM fungi and other beneficial symbiotic/non-symbiotic microbes in and around the roots.

Vaccination is one of the most effective ways to protect dogs from potentially life-threatening diseases. It plays a crucial role in controlling infectious diseases and helps maintain both individual and herd immunity. Timely and appropriate vaccination of dogs not only safeguards their health but also prevents the spread of diseases to other animals and even humans in some cases. This article provides a detailed vaccination schedule for different diseases of dogs, including core and non-core vaccines, and highlights the importance of adhering to a proper vaccination regimen.

Vaccination is categorized into two main types: core vaccines and non-core vaccines. Core vaccines are considered essential for all dogs, regardless of their lifestyle or environment, while non-core vaccines are given based on individual risk factors like geography, lifestyle, and exposure to certain environments.

The world turned into a grossly inhabitable during the infamous COVID-19 pandemic, with community health issues everywhere. Each one felt unsafe if other earthly inhabitants were, be it humans or other living beings. Onset of SARS CoV-2 set a ‘new normal’ world order. The ever-evolving and mutating SARS CoV-2 variants extended the pandemic wave after wave thereby complicating the situation, pushing the global healthcare system to its limits and exposing its underbelly. The continually evolving variants were more aggressively transmissive and infective. As the world still reels under tremendous healthcare pressure, other infectious diseases are emerging as are identified by the World Health Organisation (WHO), creating international health emergency situations. The situation becomes alarming with the increasing zoonotic (spillover) and reverse zoonotic (spillback) factors being more proactive in the disease spread. There is a greater need to vaccinate not only humans but also animals, especially the domesticated ones and known reservoirs/carriers. Vaccines must be developed on priority and equitably distributed as the first step to counter a pandemic or potential pandemic. Vaccination is self-limiting due to increasing reported breakthrough infection cases. A strong link of the environmental health to the overall global health needs to be acknowledged, and due diligent measures taken. Hence, there is a strong need of the One Health approach as a 360° solution, and follow it up at global-scale both in letter and spirit. This chapter discusses spillover and spillback of diseases like SARS-CoV-2 and Mpox as case examples, the mitigation strategies and the need for workable One Health models, and challenges and measures to counter future outbreaks. It stresses on foolproof vaccination strategies across to catalyse individual and herd immunities for universal wellbeing.

The process of vaccine development involves numerous stages from research, discovery, innovation, formulation, testing, mass production, logistics, deployment and administering the vaccine to the target population. The COVID-19 pandemic expedited the endeavour to develop vaccine worldwide that is unparalleled in history. In addition to the steps that were similar during the usual vaccine development process, it called for stronger collaborative teamwork with stricter deadlines during the pandemic due to the emergency situation that built up everywhere (in its spread as well as severity). Research was expedited, potential candidate vaccines were discovered and the proofs of concept were designed that paved the way for pre-clinical efficacy testing. Multiple-step clinical trials to ascertain that the vaccines were effective and safe at least for ‘emergency use’ in human subjects were carried out swiftly. The emergency usage regulatory approval and recommending the usage pattern involved accelerated review procedures. It immediately followed rapid scaling-up for increased production in order to meet the need to save as many human lives as possible across the globe. The approved vaccines were simultaneously evaluated for safety through dedicated pharmacovigilance systems. The future of vaccine development shall also focus on improving the worldwide access to vaccines, managing the virus variants and streamlining mass vaccination campaigns. Comprehending the research, development and administration phases to create and implement life saving vaccinations within the regulatory framework amid international health emergencies as encountered during the COVID-19 pandemic and the enormous collective endeavours are highlighted in this chapter.

Introduction
The discovery of antibiotics and their subsequent use in combating infectious diseaseswas amedical breakthroughin the 20th century, as it completely changed the treatment approach to infections in general and bacterial infections in particular. In 1928, Alexander Fleming discovered Penicillin that started the started the so-called “golden age of antibiotic”. However, later in course of time the underuse, overuse and misuse of antibiotics in medical and veterinary practice led toemergence of drug-resistant pathogens resulting in phenomenon called antimicrobial resistance (AMR). In last few decades AMR has evolved silently and now threatening the human and animal health and has acquired the potential to be a next pandemic. AMR develops in a microorganism (e.g., bacteria, viruses, fungi, parasites) when it accumulates genetic changes over time and fails to respond to antibiotic(s) leading to severe illness and mortality due to infection. Although, AMR is an evolutionary event occurring naturally in microbes, but inappropriate use of antibiotics in humans and animal medicine act as key driver to its spread. Global antibiotic consumption increased between 2016 and 2023, with total consumption rising by 16.3% to 34.3 billion defined daily doses (DDDs) in reporting countries and a projected 20.9% increase when extrapolated to nonreporting countries. World Health Organization (WHO) and other authorities have called for coordinated action to address antimicrobial resistance, a threat looming large on horizon. In 2021, there were an estimated 1.14 million deaths attributed directly to Antimicrobial Resistance (AMR), with globally another 4.71 million deaths associated with AMR infections. This dataindicates a significant global health burden, with prophecy that AMR deaths could increase dangerously by 2050 if current trends continue. Global Action Plan (GAP) of the WHO highlights the importance of “One Health approach” calling for the joint action in human health, food production, animals and environmental sectors, to achieve better results. In the year 2015, the WHO initiated the Global Antimicrobial Resistance and Use Surveillance System (GLASS)to collect, analyze and share AMR data received from all countries. The Global Action Plan on AMR lists five strategic objectives to contain AMR viz., 1. optimizing the use of antimicrobials, 2. preventing infections (including the use of vaccines), 3. strengthening surveillance and research, 4. improving awareness and understanding of AMR, and 5. investing in new medical products. Vaccines stimulate the body’s immune system to recognize and attack specific pathogens and thus can prevent AMR through several ways viz., 1. reduce the incidence of infections leading to reduction in morbidity and mortality, 2. vaccines can prevent secondary bacterial infections e.g. Streptococcus pneumoniae after an initial infection with influenza, 3. produce herd immunity, 4. Prevention of infections resulting in decrease in use of antibiotics that reduces development of AMR. Immunotherapeutics can both combat and be complicated by Antimicrobial Resistance (AMR). Other immunotherapies antibodies, and immune-boosting agents can directly fight AMR by preventing infections and reducing the need for antibiotics.

Diseases of livestock cause massive economic losses in terms of reduced productivity and production and some of them have zoonotic potential posing a serious risk to public health. Vaccination is the most efficient and cost-effective method of controlling infectious diseases both in humans and animals. The eradication of smallpox and rinderpest from the globe; the elimination of hog cholera and brucellosis from many countries; and the control of diseases such as foot-and-mouth disease, canine distemper, rabies, influenza, and pseudorabies would not have been possible without the use of effective vaccines. Vaccination not only protects the vaccinated animals but also reduces disease among non-vaccinated animals through herd immunity. They also reduce antimicrobial usage and minimize the risk of antimicrobial resistance. Vaccines Vaccines are prepared antigens to be used to prevent diseases caused by bacteria, viruses, fungi, mycoplasma, protozoa, and parasites.

A. Answer the following.

Q.1.     How many types of polio virus are there ?
Ans.    There are 3 serotypes of polio virus namely polio virus type 1, 2 and 3.

Q.2.     Who first developed inactivated polio vaccine ?
Ans.    Jonas Salk.

Q.3.     Who first developed attenuated oral polio vaccine ?
Ans.     Sabin.

Q.4.     What are the different inactivating agents used to inactivate viruses in preparing vaccines ?
Ans.    Formaldehyde, b-propiolactone and ethylenimines.

In its original concept, vaccination aims to mimic the development of naturally acquired immunity by inoculation of nonpathogenic but still immunogenic components of the pathogen in question, or closely related organisms. The term “vaccine” (from the Latin term “vacca,” meaning cow) was first coined by Edward Jenner to describe the inoculation of humans with the cowpox virus to confer protection against the related human smallpox virus and illustrates the close relationship between human and animal infectious disease sciences. The famous proverb saying ‘Prevention is better than cure’ implies perfectly to the vaccines. Vaccines have proven to be boon for animals which can be regard a potential weapons against infectious diseases caused mainly by bacteria and viruses. The major aims of veterinary vaccines are to improve the health and welfare of companion animals, increase production of livestock in a cost-effective manner, and prevent animal-to-human transmission from both domestic animals and wildlife. Vaccines have long been used to combat infectious disease; however the last decade has witnessed a revolution in the approach to vaccine design and development. Apart from improving animal health and productivity, veterinary vaccines have a significant impact on public health through reductions in the use of veterinary pharmaceuticals and hormones and their residues in the human food chain.