eChapters

Metabolic disorders are classed as illness associated with a failure in one of the body hormone or enzyme systems, storage disease related to lack of metabolism of secretory products because of the lack of production of a specific enzyme, or the failure or reduced activity of some metabolic function. There are numerous genetic, metabolic disorders in poultry but these are rare in commercial poultry. In poultry it is usual to include under the heading of metabolic disorders those conditions associated with increased metabolism, rapid growth rate or high egg production that result in the failure of a body system because of the increased work-load on that organ or system. Metabolic disorders that result from an increase production of, or deficiency of or failure in the production, synthesis, or transport of an enzyme, hormone or secretary mechanism. Metabolic disorders that result from high nutrient intake, rapid growth, high metabolic rate, pulmonary or systemic hypertension, and high egg production or a rapid increase in egg production. Other conditions that could be classed as metabolic disorders related to: (a) management defects; (b) nutritional deficiency or excess; (c) infectious agents; (d) toxins.

Introduction

Disorders of the hemopoietic system in poultry can significantly impact the health and productivity of these birds. The hemopoietic system is responsible for the production of blood cells, including red blood cells, white blood cells, and platelets. Disorders within this system can lead to various health issues, including anemia, immunodeficiency, and impaired blood clotting. Some of the common disorders of hemopoietic system include:

1. Anemia: Anemia is a condition characterized by a decrease in the number of red blood cells or hemoglobin in the blood. In poultry, anemia can be caused by various factors, including nutritional deficiencies (such as iron deficiency), infectious diseases (such as avian malaria or chicken infectious anemia), and parasitic infestations (such as blood-sucking parasites like leucocytozooncaulleryi, ticks, lice and mites).

2. Avian Leukosis:Avian leucosis is a viral disease caused by avian leukosis virus (ALV). It primarily affects young birds, causing tumors in various organs, including the spleen, liver, and bursa of Fabricius. Avian leukosis can lead to immunosuppression, anemia, and increased susceptibility to secondary infections. The avian leucosis diseases include lymphoid leucosis (affecting lymphoid cells), myeloid leucosis (affecting myeloid cells), osteoptrosis, etc. and can result in immunodeficiency, increased susceptibility to infections, and other systemic symptoms. It also affects blood-forming tissues, including the bone marrow and lymphatic system, leading to an overproduction of abnormal white blood cells.

Introduction

Eye

Avian ocular apparatus includes eyeball, optic nerve, and accessary structures e.g., eyelids, lacrimal glands, and muscles etc. The eyeball is composed of three tunics namely the f ibrous (cornea and sclera), vascular (choroid, iris, ciliary body) and nervous tunic (retina). The histological structures of all these tunics are similar to mammals except the Bowman’s membrane (the basal lamina of corneal epithelium) is not distinct. Similar to the mammals, they also have three refractive media viz., aqueous humour, lens, and vitreous humour. The cornea does not refract light.

There are some important diseases and disease conditions of eye in poultry birds. The common aetiology of eye diseases in poultry birds has a wide range and includes heredity, nutritional deficiency, infections (microbial and parasitic) and managemental failure. Some of them are not seen often in the modern intensive rearing systems like the deficiency diseases while others are seen associated only with the intensive system housing of birds like the ammonia burns. The infectious diseases of only eyes, are not encountered in poultry birds. The diseases like the colibacillosis, pasteurellosis and Marek’s disease can affect eyes along with other body systems. Understanding of eye diseases of poultry birds requires basic knowledge of ophthalmic anatomy, concepts and terminology of eye associated pathological changes. The affected birds generally show ocular lesions and loss of condition due to starvation as they are unable to search for feed and water. Some conditions are reversible while others may be irreversible according to the extent of damage. Nutritional and managemental diseases in most cases are relatively easy to diagnose and manage, while infectious and hereditary diseases may require deeper investigation. Some diseases like endophthalmitis, eye notch syndrome and ophthalmopathy have been recorded but their causes could not be found out.

The skin of the birds provides a physical barrier between the birds its environment, protecting the birds from bacteria and physical injury. The health of the bird can be compromised, and the value of the end-product can dramatically decrease. Bird’s skin differs from that of mammals by its thinness, by the presence of feathers instead of hair, and by the absence of sebaceous glands (sweat glands), although the overall histological structure is similar. Bird’s skin is composed of an epidermis separated from a dermis by a basal membranes to protect the body from infection. The integumentary system consists of the skin, the feathers and the appendages (claws and beak). The skin covers the majority of the body and contains glands in the outer ear canal and the preen gland at the base of the tail, that the bird uses to preen its feathers. The integumentary system is very important in providing protection to the bird from a number of potentially dangerous situations. The functions provided by the integumentary system include: A barrier between the external environment and the internal systems and organs thus provides support and protection from infection by microorganisms and from physical injury. Excellent thermal insulation to help regulate body temperature in a variable environment. Numerous nerve endings for the senses to enable the bird to be aware of potentially harmful situations. Pigments for display and protection from the elements. The compounds capable of conversion into vitamin D when exposed to sunlight. Avian skin is relatively thin with the epidermis consisting of only 2-10 cell layers. There are no sweat glands; instead heat is lost via the respiratory tract and by radiation from featherless areas. The brood patch is a featherless area that can occur in both sexes and is either seasonal or permanent depending on species.

Introduction

Pain management in poultry is an important aspect of animal welfare and overall production efficiency in the poultry industry. Poultry birds, such as chickens and turkeys, can experience pain due to various reasons including routine management procedures, injuries, and diseases. Managing pain in poultry is crucial not only for ethical reasons but also because pain can lead to decreased productivity and increased susceptibility to diseases. For the better management First step is identification of pain in birds which can only be possible with the thorough knowledge of their behaviour. Second step is the selection of appropriate analgesics and their dosing’s as there are various species of birds. Commonly used analgesics for birds includes, NSAID’s, opioids etc.

1. Routine Management Procedures: Many routine procedures in the poultry industry, such as beak trimming, toe clipping, and wing clipping, can cause pain and distress to birds if not done properly. Beak trimming, for example, is often performed to reduce feather pecking and cannibalism in crowded conditions but can cause acute pain if not done correctly. Proper techniques and pain management strategies must be employed during such procedures to minimize pain and distress in birds.

Introduction

The reproductive system is fundamental to poultry production, playing a crucial role in both the quantity and quality of eggs laid. Its importance goes beyond mere biology, impacting the profitability and long-term sustainability of poultry operations (Abbasi et al., 2024). Central to this is the egg, the ultimate product of avian reproduction. The reproductive system coordinates complex processes to ensure eggs meet high standards. Any disruption to this delicate balance can have far-reaching effects on the economic and environmental aspects of poultry farming. Disorders affecting the avian reproductive system pose significant challenges to the poultry industry. Whether they are minor disturbances or major disruptions, these disorders can undermine the foundation of successful production. They can lead to reduced egg production and compromised egg quality, affecting productivity, efficiency, and ultimately, profitability. In today’s poultry management landscape, where efficiency is paramount, the impact of reproductive disorders cannot be overstated. Beyond economic concerns, these disorders also affect sustainability and environmental responsibility. A healthy reproductive system is not only crucial for financial success but also for upholding ethical and responsible poultry practices. As such, ensuring the reproductive health of poultry is of utmost importance. It requires dedicated effort, attention to detail, and a comprehensive approach. By strengthening the reproductive system against various threats, poultry producers can secure not only the current success of their operations but also a legacy of responsible stewardship for future generations (Habibi et al., 2024).

Poultry, encompassing a wide range of domesticated birds, plays a crucial role in agriculture, providing meat and eggs to populations worldwide. The health and well-being of poultry are of paramount importance for sustainable and efficient production. One aspect that significantly influences poultry health is the condition of their wings. Wings serve various purposes for birds, including flight, balance, and protection. Disorders affecting poultry wings can arise from a multitude of factors, ranging from nutritional imbalances to infectious agents and environmental stressors.

Understanding and addressing poultry wing disorders require a comprehensive approach that encompasses both preventive measures and therapeutic interventions. This comprehensive understanding involves recognizing the various disorders that can afflict poultry wings, their causes, symptoms, and potential treatments. In this exploration, we delve into 50 multiple-choice questions and answers covering a diverse array of poultry wing disorders, providing insights into the complexity of avian health management.

The Significance of Poultry Wing Health

Maintaining the health of poultry wings is not merely a matter of ensuring their ability to f ly; it is intrinsically linked to the overall well-being of the bird. Poultry wings are vital for performing a myriad of daily activities, including foraging, preening, and maintaining social hierarchies within flocks. Additionally, the condition of the wings often reflects the bird’s general health status, making them an essential diagnostic indicator for avian health professionals.

Introduction The urinary system of poultry, consisting of the kidneys, ureters, and cloaca, is essential for removing waste products and maintaining fluid balance. However, this system can be susceptible to various disorders that can impact the health and productivity of the flock. This chapter will discuss some of the most common urinary system disorders in poultry.

Urinary system disorders can have significant negative impacts on poultry health and productivity (Klybeck, n.d; Mississippi State University Extension, n.d; Poultry Hub, n. d.). Some of the key ways these disorders affect poultry include:

1. Gout: Renal diseases often lead to gout in poultry, which is a metabolic disorder resulting in hyperuricemia and deposition of uric acid or urates in tissues (Klybeck, n.d.). This can further damage the kidneys or other body systems.

2. Reduced productivity: Gout has a direct effect on productivity by lowering weight gain, increasing feed conversion ratio (FCR), and causing mortality which may reach 11-30% (Klybeck, n.d)

3. Organ damage: Accumulation of uric acid can lead to swelling and damage of kidney cells, as well as visceral gout where whitish deposits are found on the surface of organs like the heart, liver, intestines, and lungs (Klybeck, n.d; Mississippi State University Extension, n.d.).

4. Mortality: Severe kidney damage and dysfunction can quickly lead to debilitation and death in poultry (Poultry Hub, n.d.). Acute septicemic coliform infections may also cause sudden death (Mississippi State University Extension, n.d.)

5. Respiratory issues: Infectious bronchitis virus can affect both the respiratory and urinary systems, causing inflammation and damage to the kidneys (Mississippi State University Extension, n.d.).

Introduction

Musculoskeletal diseases in poultry are often exhibited as lameness or leg weakness. Numerous factors, including those related to diet, animal husbandry, infections, or heredity, might contribute to musculoskeletal problems. Lameness can be exhibited due to disorders in the central or peripheral neurological systems, reproductive system, trauma or infection in the foot, leg, hip, spine, or just a generalised sickness. Less frequently, musculoskeletal anomalies can affect the bird’s beak, neck, or wings. The diseases can also be classified as infectious origin (bacterial, viral) or non-infectious origin (congenital deformities, nutritional, trauma or neoplasia). Modern poultry production lines put a lot of strain on the musculoskeletal system due to factors like growth rate in broiler chickens and egg output in laying hens. As a result, poor nutrition and husbandry practices frequently lead to musculoskeletal disorders. Thus, musculoskeletal disorders in poultry can be controlled by choosing proper genetic selection, efficient vaccinations, adequate nutrition and proper husbandry practices.

Introduction

Hepatocytes are tiny cells that constitute the primary structural unit of the liver. Periportal hepatocytes, the first to receive blood from the portal system, are particularly vulnerable to hepatotoxins and endotoxins. Periacinar hepatocytes, placed further away from the portal blood supply, are more susceptible to hypoxia, toxic metabolites and hypoperfusion. Inflammatory cells are drawn to injured hepatocytes and biliary epithelium due to the release of cytokines and inflammatory mediators. This causes additional hepatocyte necrosis and fibrosis. The liver has exceptional regenerative abilities as hepatocytes can be replaced even if only 12% remains intact.

Hepatocytes exhibit colour changes when they are laden with fat or pigments. In their f irst week of life, young turkeys and chickens typically have a lot of fat and pigments (carotenoids) deposited in the liver due to the ability of intestines in mobilizing the yolk content. It is typical to find fat vacuoles (microscopic fat deposits) within the hepatocytes at this point. A bird's liver will typically turn mahogany-brown after about seven days of life. Because of the influence of oestrogens, the hormones that are present in large concentrations once maturity is attained, the quantity of fat in the liver of adult hens increases before the age of lay. Because a large amount of fat and pigments are transferred from the liver to the oviduct for yolk formation in eggs, the majority of laying hens in a flock will typically have a pale brown or yellowish liver. When liver seems pale or yellow, histopathology is a crucial technique that can be used to establish a differential diagnosis.

Introduction

The digestive system of the birds has modifications to facilitate the easy flight. Length of intestine in birds is relatively shorter compared to mammals. Also, they lack teeth and jaw muscles which are replaced with light weight beak. Food grains are swallowed as whole and ground in the gizzard with the help of powerful muscles. In the mouth, tongue is used to manipulate the food and also aids in swallowing the food. Chickens have as many as 300 taste buds. The elementary system in birds consists of gastro intestinal tract and the accessory glands, the course of the elementary starts with Mouth, oesophagus, crop, proventriculus (glandular/true stomach), gizzard (mascular stomach), small intestine (duodenum, Jejenum, ileum), large intestine (colon and caeca) which lastly opens into cloaca. For fast growing poultry species elementary system is very important. It plays vital role in digestion, absorption and also provides protective immunity. Poultry intestines harbours diversified microflora which aids in enhanced availability of nutrients to the bird. Intestinal wall contains four layers: mucosal, submucosal, muscle tunic, and the serosal layer. As intestine is involved in important functions like digestion & immunity, any change in intestinal integrity / microflora balance impacts the bird performance in terms of body weight gain in broilers and egg number in layers. Some bacteria, viruses and also fungi produce different diseases / conditions in poultry birds. The ban on the use of antimicrobial growth promoters has pushed poultry producers from use of AGP’s to alternatives to AGP’s such as prebiotics, probiotics, essential oils and some herbals. Maintaining good gut health in the absence of AGP’s and anticoccidial drugs is a challenging situation for the poultry farmers across the globe. Poultry gut contains diverse community of bacteria, fungi, protozoa and viruses. The recent data suggests that gastrointestinal tract of a broiler chicken colonizes by an estimated 600 – 800 species of bacteria. The abundance and diversity of microbiota varies along the GI tract. After the hatch GI tract colonizes within 3-4 days. Small intestine of broilers mainly contains lactobacilli although enterococci, E.coli, eubacteria, clostridia, propionibacteria and fusobacteria can be found.

Introdcution

Poultry have a nervous system made up of the brain, spinal cord, sympathetic nerves that govern their viscera, and branches that go to their ears and eyes. The structure of the brain and spinal cord is very similar to that of mammals. However, there are also significant structural variations between many bird brains and many human brains, including the following:

1. Absence of cortex: According to Cobb (1960), the cortex is “a peripherally placed coating (pallium) of cells arranged in layers,” yet it is completely absent in birds. However, other authors have compared the hyperstriatum to the mammalian cortex (Haefelfinger, 1957; Stingelin, 1958).

2. Presence of hyperstriatum: The functions of the hyperstriatum are comparable to those of the mammalian cortex. In pigeons and chickens, the hyperstriatum may be involved in the visual and hearing systems’ functions.

3. Birds have highly developed optic lobes.

4. Turkeys and vultures are the only birds with a well-developed olfactory system.

Introduction

Ante mortem diagnosis of cardio vascular diseases in avian patients is a challenging to the physician. Compare with the mammals, few anatomical and physiological features are unique in birds. The avian heart is anatomically similar to mammals, although birds have a proportionally larger heart size relative to a comparably sized mammal. Heart size in mammals remains equivalent to body mass, while larger birds have a proportionally smaller hearts in relation to body size than smaller birds. The apex of the heart is enclosed between the right and left hepatic lobes and lies along the sternum and parallel to the thoracic spine in the cranio ventral coelom. The avian cardiovascular system is adapted to the high aerobic requirements for flight, running or swimming. Efficient oxygen transfer to the tissues is facilitated by a lower total peripheral resistance, higher heart rate, higher arterial blood pressure and more rapid myocardial depolarization. The clinical signs seen in birds afflicted with cardiac disease can be vague and non-specific which are mimicking many other disease conditions. Similar to mammals, birds may present with lethargy, weakness, exercise intolerance, syncope, dyspnoea, coughing and even sudden death. On physical examination cardiac disease may be suspected based on the presence of arrhythmia, murmur, muffled cardiac sounds, poor peripheral pulses, cyanosis and coelomic distension. Pulmonary oedema, hepatomegaly, ascites and enlarged jugular veins with pulsation may be seen in cases of congestive cardiac failure. Pericarditis can occur with primary infectious agents or secondary to disease occurring in adjacent tissues, such as mycotic pulmonary granulomas. Visceral gout due to hyperuricaemia may also affect the pericardium. Congestive heart failure and systemic manifestations of disease, such as hypoproteinaemia, may result in effusions within the pericardium. Myocardial ventricular hypertrophy can occur with any condition that results in an elevated preload on the heart, including pulmonary hypertension and atherosclerosis. Myocarditis has been observed in cases of chlamydiosis, polyomavirus infection and proventricular dilatation disease from bornavirus. Heavy metal toxicosis has been associated with cardiac neural dysfunction and myocardial infarction. Vegetative endocarditis and resultant valvular insufficiency can occur with bacteraemia from chronic bacterial infections involving other organ systems.

Introduction

Poultry are domesticated birds mostly reared for the purpose of meat and egg consumption as well as for their feathers. It includes chickens, quails, turkeys, waterfowls, ducks and geese. The endocrine system of poultry consists of hypothalamic-hypophyseal complex, parathyroid gland, thyroid gland, pancreatic islet cells, adrenal glands, ultimobranchial glands, endocrine cells of gut and the gonads. These endocrine organs release hormones into the bloodstream. Peptide hormones act on the surface of cells, whereas steroid hormones act on target tissues by entering in the cytoplasm or nucleus of cells. Lack of diagnosis in the case of endocrinopathies is a major cause of production loss globally. Advancement in awareness, diagnosis, treatment as well as management is critical to ensure optimal flock health. Cost-effective programs of biosecurity and vaccination are required to prevent or limit the impact of disease. Programs of emergency treatment and long-term prevention are justified for severe endocrine diseases which have a profound impact on production.

Introduction

Knowledge of the avian respiratory system is essential for developing a health monitoring plan for a poultry flock, recognizing problems that may occur, and taking action to correct them. The avian respiratory system begins with nostril includes trachea, bronchi (bronchus) and ends with lungs and air sacs. Respiratory diseases are the most common cause of death in a poultry flock.

The avian respiratory system is involved in the following functions:

• Absorption of oxygen (O2)

• Release of carbon dioxide (CO2)

• Release of heat (temperature regulation)

• Detoxification of certain chemicals

• Rapid adjustments of acid/base balance

• Vocalization

ELECTROLYTE BALANCE

Electrolytes like sodium, potassium, and chloride are substances that dissolve into posi tively and negatively charged particles when mixed with a liquid. The interaction between these substances, referred to as the ‘dietary electrolyte balance (DEB), can be influenced by either the electrolyte itself or the additional salt source used.

Dietary inclusion of potassium and chloride has shown positive effects on heat-stressed broilers. Among various salt options for broiler diets, sodium bicarbonate and potassium chloride have been identified as the optimal choices, especially during hot summer conditions.

Electrolyte balance is often quantified by the uncomplicated equation Na + K – Cl expressed in terms of mEq/kg of diet. An ideal overall dietary equilibrium ranging from 240 to 260 mEq/kg is generally deemed optimal for normal physiological functioning. The body’s buffering systems play a pivotal role in maintaining a close-to-normal physiological pH, thus preventing deviations in electrolyte levels. The principal function of electrolytes pertains to the regulation of body water and ionic equilibrium. Consequently, the requisites for elements like sodium, potassium, and chloride can’t be viewed in isolation; it’s the collective equilibrium that holds significance. The term “electrolyte balance,” synonymous with acid-base balance, is influenced by three factors:

1. The equilibrium and proportion of these electrolytes in the diet.

2. Endogenous production of acids.

3. The pace of renal clearance.

Introduction

A thoroughly performed physical examination in poultry and avian clinical practice is of great importance. Most avian species happen to be prey animals, with the exception of a few raptors that tend to be predatory. This makes them try to appear healthy, in preparation to escape from potential predators, and as such, makes it difficult for their owners, keepers and veterinarians to detect early diseases. Physical examination when carefully performed in detail, increases the chances of obtaining fewer differential diagnosis that are likely to be harboring the confirmatory diagnosis after laboratory works are being performed. In essence, a thorough physical examination brings about cost efficiency in poultry/ avian clinical practice. Take for instance, a farm with over 50,000 layers, having lowered productivity. It will be cumbersome to go ahead and start blood sampling, faecal sampling or oral cavity swabs for laboratory analysis as the starting point. The disadvantages will be high labour demands, high capital demands, more stress on the animals and of course, long time till feasible outcome is to be obtained.

Introductioin

Poultry diseases can be caused by bacteria, viruses, fungi, parasites, or a combination of these pathogens. Common poultry diseases include Newcastle disease, avian influenza, infectious bronchitis, infectious bursal disease, coccidiosis, and salmonellosis, among others (Grace et al., 2024). These diseases can affect various organs and systems in poultry, including the respiratory, gastrointestinal, and immune systems, leading to a wide range of clinical signs and symptoms (Dunislawska et al., 2024). Prevention and control of diseases in poultry is paramount for maintaining the health and welfare of poultry f locks and ensuring the sustainability of the poultry industry. Poultry diseases can have devastating effects on production, leading to decreased productivity, increased mortality rates, and significant economic losses. Therefore, implementing effective prevention and control measures is essential for poultry producers to mitigate the risks associated with diseases (George & George, 2023).

Any abnormal condition, which affects the normal functioning of cells, tissues, organs and any other system in an individual, is called a disease. In all living organisms, including plants, animals, birds and humans, diseases can be caused due to infectious or non-infectious agents and various other factors. Laboratory tests may identify organisms directly (eg, visually, using a microscope, growing the organism in culture) or indirectly (eg, identifying antibodies to the organism). Some tests (eg, Gram stain, routine aerobic culture) can detect a large variety of pathogens and are commonly done for many suspected infectious illnesses. However, because some pathogens are missed on these tests, clinicians must be aware of the limitations of each test for each suspected pathogen. In such cases, clinicians should request tests specific for the suspected pathogen (eg, special stains or culture media or advise the laboratory of the suspected organism(s) so that it may select more specific tests. The main causative factors of diseases in humans include internal factors, genetic irregularities, allergies, poor immune system, external factors and a lot more.

Introduction

The current health situation in poultry farming is dotted with cases where these emerging or re-emerging diseases attack birds. A large majority of them are of viral origin and a powerful immunosuppressive effect is observed, sometimes accompanied by bacterial infections. Most of the important infectious diseases of poultry have been known for many years and are controlled by medication, vaccination, eradication and bio-security. Examples of such diseases that were known before the intensive commercial poultry industry development are infectious bronchitis (IB), newcastle disease (ND), infectious bursal disease (IBD), lymphoid leucosis and so on. From time to time, new diseases emerge to provide fresh challenges for diagnosis, control and understanding of their epidemiology.

World Health Organization (WHO) definition of an emerging disease is defined as a disease that has appeared in a population for the first time, or that may have existed previously but is rapidly increasing in incidence or geographic range. Diseases that reappear after a period of absence can be considered as re-emerging. Some of these include runting/ stunting syndrome and inclusion body hepatitis. In addition, other well-established diseases evolve in different ways and can also present problems for diagnosis and control. In the wider sphere, it is recognized that emerging viral infections in both humans and animals have been reported with increased frequency in recent years. Examples are SARS, avian influenza, West Nile virus and the Nipah virus. The more recent diseases of viral origin, others that have re-emerged and some experiences from previous emerging diseases are living examples for threat to the poultry industries. In addition, infectious bronchitis is an example of a disease which the causal virus is showing constant evolution. The impact of infections caused by the avian metapneumovirus (aMPV) is an example of recently emerged viral agent.

Introduction

The quality of interaction between clinicians and microbiologists has an enormous influence on the effectiveness of the laboratory service. An accurate diagnosis is based on the interpretation of both clinical and laboratory data. Investigation of disease is solely dependent on the quality and appropriateness of the specimens collected. The diagnosis depends on the skill and care with which the clinicians select, collect and transport the specimen to the laboratory. Clinical history, including the tentative diagnosis, should always accompany the specimen. If available, a detailed post-mortem report must also be sent. These set of information will help the microbiologist to select the most appropriate procedure and to furnish a meaningful interpretation of the results.

Specimens need to be collected for establishing a disease diagnosis or monitoring of vaccine response or surveillance. The knowledge of the pathogenesis of the infectious disease is the most important factor for determining the most suitable specimen. The samples need to be appropriate, and adequate in number and amount to provide a statistically valid result. Samples must be taken with care, to avoid undue stress or damage to the bird or danger to the operator. Careful consideration must be given to the collection, containment, and storage of the specimens, including biosafety measures to prevent spillage to the environment or exposure of other birds and humans.

Introduction

The control of infectious diseases of bacterial etiology in food animals is often by using collective and simultaneous medication of a group, i.e. the so-called preventive uses prophylaxis and metaphylaxis. These uses are vigorously debated because they involve the mass consumption of antibiotics that is suspected to favour the emergence of resistant bacteria, especially in the gut flora, which is critical for the potential transfer of resistance to humans via the food chain. Metaphylaxis corresponds to the administration of antibiotics to animals experiencing any level of bacterial disease before overt disease occurs, with the time of intervention depending on the detection of disease outbreaks in a few animals in the group. Metaphylaxis is launched after (meta) pathogen contamination, with the goal of the bacteriological cure of infected animals, which subsequently warrants the final protection (phylaxis) against infection outbreaks. In this respect, metaphylaxis should be viewed as a curative treatment occurring early in the time scale of the infection, and should be compared to classical curative treatments of sick animals. The pathophysiological status of the animals and the size of the bacterial load at the infection site are specificities of metaphylaxis that could play an important role in antibiotic pharmacodynamics, including the reduction of resistance selection within the pathogenic inoculum. Recent advances have been made in evaluating the antibiotic doses required for clinical and bacteriological cures, depending on the size of bacterial load at the infection site. The observations that total doses were much lower for early treatments when bacterial loads were small, compared to later treatments of sick animals with higher bacterial loads, reinforces the in vivo relevance of the so called ‘inoculum effect’, whatever its underlying mechanisms.

Introduction

The protozoa (meaning proto- first and zoa mean animals) are considered to primitive and are unicellular organism. The protozoa are Eukaryotic organism having nucleus in which the genetic information is stored in chromosomes of nucleus. In poultry, the protozoan disease categorized into two main group

1. Intestinal protozoan parasites include Eimeria spp. (Coccidiosis), Cryptosporidia (Cryptosporidiosis) Histomoniasis (Histomonas meleagridis), Trichomoniasis (Trichomonas spp.) and Spironucleus (Hexamitiasis).

Coccidiosis is important disease of poultry caused by protozoa of the genus Eimeria. The disease occurs by ingestion of sporulated oocyst ehcih upon action of trypsin rupture in gizzard and proventriculus relealeses sporozoites. The sprozoites penetrate mucosa of intestine and two generation of asexual reproduction occurs (Schizogony) and releases merozoites which mature and produces gamonts. Sexyual reproduction occurs (Gametogony) and produses zygot which mature to form oocysts. The oocysts are passed in faeces. The high moisture (exceeding 30%), immunosuppressive diseses and environmental and managemental stress lead to occurrence of disease. The birds affected with coccidiosis show depression, ruffled feathers, blood tinged diarrhoea and pale comb and wattle. Specific part of intestine is affected by each species of Eimeria. Diagnosis of coccidiosis is done by finding oocyst in faeces under microscope.

Introduction

Rickettsial diseases in poultry are caused by various species of bacteria belonging to the genus Rickettsia. These diseases can have significant economic implications for the poultry industry due to decreased production, increased mortality, and trade restrictions. Rickettsial diseases affecting poultry are relatively uncommon compared to other pathogens but can still occur. Rickettsial organisms are tiny, pleomorphic, weakly gram-negative bacilli that multiply by binary fission. The Rickettsia requires an arthropod for transmission and to complete its life cycle. The organisms are non-motile and non-capsulated and possess both DNA and RNA. Some of the rickettsial diseases affecting poultry include:

1. Rocky Mountain spotted fever: Chickens can be infected with various species of Rickettsia, including Rickettsia rickettsia, which causes Rocky Mountain spotted fever in humans. In chickens, rickettsial infections can lead to symptoms such as fever, lethargy, decreased egg production, respiratory distress, and neurological signs.

1. Prosthogonimus pellucidus is found in

a) Fowl

b) Duck

c) Both

d) None

2. Heterakis gallinarum is found in

a) Fowl

b) Pea fowl

c) Guinea fowl

d) All

Flea of Brds

Ceratophyllus gallinae – commonest flea of domestic poultry may be responsible for irritation, restlessness and even anaemia Feeds readily on humans and domestic pets and its often acquired in the handling of poultry and from injured and wild birds brought into houses could migrate into rooms from nests under adjacent caves.

Echidnophaga gallinacea -‘stick tight’ flea-seen on the skin of the fowl (usually comb and wattles). Absence of genal and pronotal comb. Fleas established in a poultry house - Remove and burn all litter them spray the poultry house with an insectide.

Mites of Birds

Introduction

Avian mycoplasmosis is caused by several pathogenic mycoplasma of which mycoplasmosis due to Mycoplasma gallisepticum (Mg), Mycoplasma synoviae (MS) and Mycoplasma meleagridis are important. The mycoplasma are group of bacteria that lack cell wall due to which the shape of bacteria is pleomorphic. Due to lack of cell wal, mycoplasma are resistant to those drug which act on cell wall and includes Penicillin and its derivatives. Mycoplasma primarily affects respiratory system and joints in birds and respiratory and urogenital system in humans. The avian mycoplasma are mainly transmitted by vertical route (egg transmission), but can also transmitted by horizontal route. Mycoplasma gallisepticum (Mg) causes chronic respiratory disease (CRD) in chicken, turkeys and game birds. Mycoplasma synoviae (Ms) causes infectious synovitis in chicken and turkeys whereas Mycoplasma meleagridis cause disease in turkey. The Mg and Ms belongs to class of Mollicutes (Molecutis: soft tissue), order Mycoplasmatales and family Mycoplasmataceae. The CRD caused by Mg affects respiratory system and air sac in presence of other respiratory pathogen/ stress or immunosuppression. Clinically, CRD affected birds show respiratory rales, gasping, nasal discharge, and rhinitis with mortality due to complication with other respiratory viral pathogens or E. coli infection. The Ms has affinity for tendon and ligaments of joint causing severe lameness due to tenosynovitis with mild lesions in respiratory system and air sac. The Ms affected birds show lameness, breast blister and increased culling of male breeder birds. The Mg and Ms causes significant losses in poultry industry due to decreased egg production, condemnation and downgrading of carcass and decreased hatchability. Mycoplasma meleagridis in turkey associated with air sacculitis and drop in egg production.

1. What is a characteristic feature of fungal cell walls?

a) Peptidoglycans

b) Ergosterol and polysaccharides

c) Antiphagocytic capsules

d) Fruiting bodies

2. How do fungi reproduce in tissues?

a) Binary fission

b) Budding

c) Simple division of round, yeast-like forms or slender, tubular hyphae

d) Spore formation

1. How does the toxin of Clostridium botulinum affect the nervous system?

a) Blocks inhibitory transmitter substance

b) Stimulates macrophages

c) Causes haemolysis and tissue destruction

d) Induces systemic shock and death

What is the specific effect of the toxin produced by Clostridium perfringens on host cells?

a) Blocks inhibitory transmitter substance

b) Induces systemic shock

c) Causes ribosomal dysfunction

d) Disrupts plasma membranes

Introduction

The Poultry industry stands as one of the most advanced sectors globally. The impact of diseases on poultry can be profoundly detrimental, affecting productivity, trade of live birds, meat and related products. Vulnerabilities in biosecurity within production sites, as well as weaknesses in disease diagnosis, pave the way for emerging pathogens to establish as persistent threats. In numerous tropical and developing nations poultry infections like viscerotropic velogenic New castle disease have become endemic, leading to disastrous losses. Many developing countries contend with a prevalence of vertically transmitted diseases among village-level flocks, including ailments like pullorum disease and mycoplasmosis. The combination of hot, humid climates fosters mycotoxicosis, compounded by prevalent immunosuppressive diseases, which in turn hinder the effectiveness of vaccination efforts. In the absence of robust quarantine measures and government – mandated control programs, disease can persist within both commercial and local flocks. The introduction of new infections further compounds the vulnerability of susceptible poultry populations.

1. Genetics is a branch of science which deals with study of heredity variation among related organism.

2. UK established the Institute of the Biotechnology.

3. ICGEB-international center for genetic engineering and biotechnology which has two center India and Italy.

4. When cross is made between two parents differing in two characters known as dihybrid cross.

5. Mendel's first law Law of segregation.

6. Mendel's second law law of independent assortment.

7. When F, cross with its parent it is known as back cross.

8. When F, cross with recessive parent is called as test cross.

9. Monohybrid test cross gives 1:1 phenotype.

10. Dihybrid test cross gives 1:1:1:1 phenotype ratio.

1. Biotechnology arises from the field of Zymotechnology.

2. The word Biotechnology was coined by Karl ereky in 1919.

3. OECD Organisation for Economic Co-operation and Development (1981).

4. National Biotechnology Board - 1982 by GOI.

5. ICGEB International Centre for Genetic Engineering and Bio-technology (1988).

6. Cohen & Boyer - Recombinant DNA technology (1973).

7. Restriction enzymes are called as Molecular scissors.

8. Frederick Sanger - DNA Sequencing techniques.

9. Modified red glow zebra fish came on to the market in 2004.

10. Tissue culture Osowski 1914.

11. The term molecular biology was used by Warren weaver.

1. The word "Statistics" derived from the Latin word 'Status' meaning POLITICAL STATE.

2. Statistics are lifeblood of successful commerce.

3. Statistics are not suitable to study the qualitative phenomenon.

4. Statistics laws are not exact.

5. A.L.Bowley "Statistics are numeral statement of facts in any department of enquiry placed in relation to each other".

6. Croxton and Cowden "Statistics may be defined as the science of collection, presentation analysis and interpretation of numerical data from the logical analysis".

7. Alfred Marshall - "Statistics are the straw only which I like every other economist has to make the bricks".

8. Function of statistics

a. Condensation

b. Comparison

c. Forecasting

d. Estimation

e. Tests of hypothesis

9. ANOVA-Analysis of Variance.

10. ANOVA-developed by Prof. R.A. Fisher.

1. Project monitoring is an integral part of project management.

2. Concurrent evaluation is carried out during implementation of the project.

3. Terminal evaluation is undertaken at the time of completion of the project.

4. Ex-post evaluation is also called as impact evaluation.

5. Network techniques are used for minimising cost and time of the project.

6. PERT-Program Evaluation and Review Technique.

7. LOT-Latest Occurrence Time.

8. CPM-Critical Path Method.

9. Project presentation - 30 pages.

10. National level project goal of economic growth.

1. A good market always serves to safeguard the interest of the trader and the consumer.

2. The core fish marketing system is classified the three types as market penetration, market development and products development.

3. College of Mangalore developed technology for fish sausages.

4. CIFE Mumbai developed technology to manufacture fish wafers.

5. Mandala committee - Gujarat.

6. Aratdars is commonly called as Commission agent.

7. Selling is also done by contract method.

8. Concentric diversification the products have technological and marketing synergies with the existing fish commodity sale.

9. Horizontal diversification-adding new product to the present products.

10. Conglomerate diversification-it is a firm seeking add new commodities to new classes of customers because this will set some of the deficiencies of old products.

1. The word Extension was first used in U.S.A.

2. The word Extension is derived from Latin meaning out stretching.

3. Extension education = non formal education.

4. Extension work out of school system of education.

5. Learning active process on the part of the learner.

6. Motivation need satisfy goal-seeking behaviour.

7. Steps in extension teaching methods = AIDCAS.

8. Teaching is the process of providing situations in which learning takes place.

9. Learning is the process by which a person becomes changes in his behaviour through self-activity.

10. Lecture is the best method for presenting information to large number of persons in a short period of time.

1. The most disaster affected populations in the world - China,

2. Heavy droughts usually occur in Afghanistan.

3. Heavy human causalities due to flood occur in Cambodia.

4. Ring of fire an arc of volcanoes and fault lines encircling the Pacific basin.

5. Occurrence of unusual cold wave Russia.

6. 22 Indian states are prone to disasters.

7. Pre-Disaster mitigation can help in ensuring faster recovery from impacts of disaster.

8. IOC-International Oceanographic Commission.

9. USGS-United States Geological Survey.

10. NOAA-National Oceanic and Atmospheric Administrations.

1. Luther Gullick denoted the functional elements of the administration POSDCORB.

2. CIFNET Central Institute of Fisheries Nautical Engineering and Training. It was started in 1963. The head quarters situated in cochin.

3. CIFNET have two units one Chennai, another one Visag.

4. IFP-integrated fishery project was started in 1952.

5. During 2008 the FPT was renamed as NIFPHTT. It has situated in cochin.

6. FSI-fishery survey of India. It has head quarter in Mumbai.

7. CICEF-Central Institute of Coastal Engineering for Fishery. It is situated in Bangalore.

8. CICEF was renamed in 1983 as PISFH-pre investment of fishing harbor

9. NFDB-national fisheries development board.established in 2006. It has head quarters in Hyderabad.

10. CAA-coastal aquaculture authority established in 2005. It has head quarter in Chennai.

11. Coastal zone regulation notification - 1991.

1. I Kilo joule - 10 joule.

2. 1 Mega joule -10º joule.

3. 1 Kilowatt hour-3.6*10 joule.

4. The heat engine converts heat energy into mechanical energy.

5. The machine which converts one forms of energy to another form is called as engine or prime mover.

6. Fahrenheit scale is called as British thermal unit and denoted by B.Th.U.

7. Internal combustion engines using coal gas as fuel was made by Frenchman Etienne Lenoir (1860).

8. Silent gas engine was developed by Germans Nileolansotto & Eugen Langen.

9. Rudolph diesel made the first diesel engine in 1894.

10. TDC is also called as inner dead centre.

1. Chromatography Technique for the separation of one or more biological compounds from the mixture.

2. Chromatography - Mikhail Tswett (1906)

3. Distribution or partial coefficient is defined as the ratio of concentration of compounds in the mobile phase to that the concentration of compounds in the stationary phase.

4. Chromatography also used for the separation of the colorless compounds from a mixture.

5. Spectroscopy employs the interaction of light with matter.

6. Light is electromagnetic radiation (EMR) that exhibit discrete packets of energy is called as photons.

7. Jablonski diagram gives the electronic and vibrational state of the molecule.

8. Molecular structures responsible for the interaction with EMR are called as Chromophores.

9. Beer's law is valid for low concentrations only.

10. Prism splits incoming light into its components by refraction.

11. Grating splits the wavelengths by diffraction.

1. Examples of grappling gears Clamps, Tongs and Raking devices.

2. Wounding gears with sharp projectiles Spears, Lances, Fish plummets, Fish comb, Arrows, Harpoons, Blow guns, Rifles.

3. Brail net-Large scoop net.

4. Jerk net a rectangular net kept under tension between two sticks which are pushed forward.

5. Collection of shells and corals for decoration and small fishes for aquarium is called as Aesthetic fishing.

6. Fish plummets are also called as plume lines or plumed lines.

7. The cross section of the two scam trawl during operation is elliptical.

8. Bridles-legs of trawl.

9. Sweep lines serve as false netting under water and vibrate in the water column.

10. The size of the trawl net is generally referred by the length of the head rope.

1. Fiber are basic material for constructing the gear.

2. Fibers length will be 200 times greater than that width.

3. Cotton fibber have length about 20-50 mm.

4. Ramie, hemp, liner are also known as soft fiber.

5. Ramie fiber - china grass.

6. Sisal and manila fiber are hard fiber.

7. Poly amide also known as nylon.

8. Polystyrene also known as terylene.

9. Poly condensation water eliminating process eg PA, PES.

10. Poly vinyl chloride is the first synthetic fiber to be produced by on an industrial scale. And also first synthetic material for gear.

1. The process of directing or conducting the movement of vessel one place to another place is known as navigation.

2. Controlling the ship is known as seamanship.

3. VHF used up to 25 nautical miles.

4. Speed of sound wave 322m/sec.

5. Speed of radio wave 3x10 m/sec.

6. Navigation derived from latin word.

7. Earliest form of navigation is piloting.

8. Dead reckoning is rough method only.

9. Radio navigation also known as electronic piloting.

10. World chart produced by Gerardus Mercator.

1. The removal of moister from the timber is known as seasoning.

2. For boat building purpose timber should have moisture about 18-20%.

3. Mild steel contain 0.15-0.30% of carbon.

4. Low carbon steel contain less than 0.15% of carbon.

5. High carbon steel contain 0.8-1.5% of carbon.

6. The specific gravity of steel 7.84.

7. The aluminum boat was firstly built in France 1892.

8. Ferro cement boat was introduced in France 1847.

9. Specific gravity of aluminum-2.7.

10. Specific gravity of Ferro cement 2.4-2.6.

1. The process of removing heat from a substances under controlled condition known as refrigeration.

2. A refrigerator is a revised heat engine.

3. Whenever a force acts on body and the body undergoes a displacement is known as work.

4. The rate of doing work-power.

5. Unit of work kgf, Nm, joule.

6. 1 HP-736 watts.

7. Energy defined as the capacity to do work.

8. 1 bar- 105N / (m ^ 2)

9. Absolute pressure gauge pressure + atmosphere pressure.

10. The degree of hotness or coolness is known as temperature.

11. The level of intensity of the body - heat.

1. Farm is complex structure comprising living and non-living things.

2. The engineering components and structures aqua farm. basic necessities of an

3. Ponds, Water transportation systems - primary structures of an aqua farm.

4. Machineries, builtin structures and other peripheral accessories secondary structuresof an aqua farm.

5. Secondary structures may vary from one pond to another pond based on the

a. Type of culture

b. Method followed

c. Economic status of the farmer.

6. Site selection - Pre-requisites of a successful aquaculture farm.

7. Soil bottom must be impervious to prevent excessive seepage.

8. Fine textured soils - a high clay content.

9. Embankment ponds are also called as Hill/ Water shed ponds.

10. Excavated ponds are principally used for the commercial fish and shrimp production.

1. In India roughly curing preserves 20% of the fish caught.

2. Salt curing is an important and one of the most widely adopted method of fish preservation.

3. Higher salt content prevents the growth of normal spoilage micro flora in the fish.

4. Salted fish reduced to biscuit cure in drying kilns.

5. Sodium chloride diffuses through the fish flesh by a dialysis mechanism & water will diffuse to the outside due to the osmotic pressure between the brine and fish muscle solution.

6. Gaspe curing is practiced in aboard, originated in eastern Canada.

7. Dry salting ratio is 1:3 to 1:10 (salt: fish).

8. Yield of dry salting is about 35-40%

9. The shelf life of the dry salted fish is about 6-10 weeks.

10. The moisture content of the wet salted fish is about 50-55%.

1. Degree of excellence referred as quality

2. More acidic pH leads to chalkiness in seer fish

3. Low post mortem pH leads to gapping

4. In squid and herring anisakis parasite normally found

5. The most crustacean parasites are copepods

6. Greasy haddock is a fungal disease caused by icthyosporidium hoferi

7. Tetra toxin is caused by V.alginolyticus

8. NSP produced by brevetoxin

9. VSP- venerupin shellfish poisoning also called as oyster or asaripoisoning it is caused by Prorocentrum sp.

10. Erythematius shellfish poisoning affect the blood circulatory system

11. The maximum permitted limit of DDT is 5 mg/ kg

1. Bacteria intoxication - already formed bacteria not live bacteria

2. Bacterial infection consumption of live bacteria

3. Neuro toxin produced by C. botulinum

4. Listeria identified by the serotyping

5. Fishery product have type E, C. botulinum

6. S. aureus produced entiro toxin

7. S. aureus is heat resistant but not active in pasteurization

8. E. coli-0157:H7

9. Salmonella should be below 105/g

10. Septicemia can occur due to the salmonella

11. L. monocytogens should be 10/ g